These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 27335215)

  • 1. Machine Learning Model Analysis and Data Visualization with Small Molecules Tested in a Mouse Model of Mycobacterium tuberculosis Infection (2014-2015).
    Ekins S; Perryman AL; Clark AM; Reynolds RC; Freundlich JS
    J Chem Inf Model; 2016 Jul; 56(7):1332-43. PubMed ID: 27335215
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Combining computational methods for hit to lead optimization in Mycobacterium tuberculosis drug discovery.
    Ekins S; Freundlich JS; Hobrath JV; Lucile White E; Reynolds RC
    Pharm Res; 2014 Feb; 31(2):414-35. PubMed ID: 24132686
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparing and Validating Machine Learning Models for Mycobacterium tuberculosis Drug Discovery.
    Lane T; Russo DP; Zorn KM; Clark AM; Korotcov A; Tkachenko V; Reynolds RC; Perryman AL; Freundlich JS; Ekins S
    Mol Pharm; 2018 Oct; 15(10):4346-4360. PubMed ID: 29672063
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Machine Learning Models for
    Lane TR; Urbina F; Rank L; Gerlach J; Riabova O; Lepioshkin A; Kazakova E; Vocat A; Tkachenko V; Cole S; Makarov V; Ekins S
    Mol Pharm; 2022 Feb; 19(2):674-689. PubMed ID: 34964633
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Predicting Mouse Liver Microsomal Stability with "Pruned" Machine Learning Models and Public Data.
    Perryman AL; Stratton TP; Ekins S; Freundlich JS
    Pharm Res; 2016 Feb; 33(2):433-49. PubMed ID: 26415647
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Combining Metabolite-Based Pharmacophores with Bayesian Machine Learning Models for Mycobacterium tuberculosis Drug Discovery.
    Ekins S; Madrid PB; Sarker M; Li SG; Mittal N; Kumar P; Wang X; Stratton TP; Zimmerman M; Talcott C; Bourbon P; Travers M; Yadav M; Freundlich JS
    PLoS One; 2015; 10(10):e0141076. PubMed ID: 26517557
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Combining cheminformatics methods and pathway analysis to identify molecules with whole-cell activity against Mycobacterium tuberculosis.
    Sarker M; Talcott C; Madrid P; Chopra S; Bunin BA; Lamichhane G; Freundlich JS; Ekins S
    Pharm Res; 2012 Aug; 29(8):2115-27. PubMed ID: 22477069
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fusing dual-event data sets for Mycobacterium tuberculosis machine learning models and their evaluation.
    Ekins S; Freundlich JS; Reynolds RC
    J Chem Inf Model; 2013 Nov; 53(11):3054-63. PubMed ID: 24144044
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enhancing hit identification in Mycobacterium tuberculosis drug discovery using validated dual-event Bayesian models.
    Ekins S; Reynolds RC; Franzblau SG; Wan B; Freundlich JS; Bunin BA
    PLoS One; 2013; 8(5):e63240. PubMed ID: 23667592
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Machine learning and docking models for Mycobacterium tuberculosis topoisomerase I.
    Ekins S; Godbole AA; Kéri G; Orfi L; Pato J; Bhat RS; Verma R; Bradley EK; Nagaraja V
    Tuberculosis (Edinb); 2017 Mar; 103():52-60. PubMed ID: 28237034
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Looking back to the future: predicting in vivo efficacy of small molecules versus Mycobacterium tuberculosis.
    Ekins S; Pottorf R; Reynolds RC; Williams AJ; Clark AM; Freundlich JS
    J Chem Inf Model; 2014 Apr; 54(4):1070-82. PubMed ID: 24665947
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Validating new tuberculosis computational models with public whole cell screening aerobic activity datasets.
    Ekins S; Freundlich JS
    Pharm Res; 2011 Aug; 28(8):1859-69. PubMed ID: 21547522
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Development of antituberculous drugs: current status and future prospects].
    Tomioka H; Namba K
    Kekkaku; 2006 Dec; 81(12):753-74. PubMed ID: 17240921
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of active molecules against Mycobacterium tuberculosis through machine learning.
    Ye Q; Chai X; Jiang D; Yang L; Shen C; Zhang X; Li D; Cao D; Hou T
    Brief Bioinform; 2021 Sep; 22(5):. PubMed ID: 33822874
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Analysis and hit filtering of a very large library of compounds screened against Mycobacterium tuberculosis.
    Ekins S; Kaneko T; Lipinski CA; Bradford J; Dole K; Spektor A; Gregory K; Blondeau D; Ernst S; Yang J; Goncharoff N; Hohman MM; Bunin BA
    Mol Biosyst; 2010 Nov; 6(11):2316-2324. PubMed ID: 20835433
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Prediction of inhibitory activities of small molecules against Pantothenate synthetase from Mycobacterium tuberculosis using Machine Learning models.
    Hassam M; Shamsi JA; Khan A; Al-Harrasi A; Uddin R
    Comput Biol Med; 2022 Jun; 145():105453. PubMed ID: 35364306
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bayesian models for screening and TB Mobile for target inference with Mycobacterium tuberculosis.
    Ekins S; Casey AC; Roberts D; Parish T; Bunin BA
    Tuberculosis (Edinb); 2014 Mar; 94(2):162-9. PubMed ID: 24440548
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A collaborative database and computational models for tuberculosis drug discovery.
    Ekins S; Bradford J; Dole K; Spektor A; Gregory K; Blondeau D; Hohman M; Bunin BA
    Mol Biosyst; 2010 May; 6(5):840-51. PubMed ID: 20567770
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Formulation studies of InhA inhibitors and combination therapy to improve efficacy against Mycobacterium tuberculosis.
    Knudson SE; Cummings JE; Bommineni GR; Pan P; Tonge PJ; Slayden RA
    Tuberculosis (Edinb); 2016 Dec; 101():8-14. PubMed ID: 27865404
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Development and validation of consensus machine learning-based models for the prediction of novel small molecules as potential anti-tubercular agents.
    Wani MA; Roy KK
    Mol Divers; 2022 Jun; 26(3):1345-1356. PubMed ID: 34110578
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.