BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 27335721)

  • 1. Hippuristanol - A potent steroid inhibitor of eukaryotic initiation factor 4A.
    Cencic R; Pelletier J
    Translation (Austin); 2016; 4(1):e1137381. PubMed ID: 27335721
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A.
    Bordeleau ME; Mori A; Oberer M; Lindqvist L; Chard LS; Higa T; Belsham GJ; Wagner G; Tanaka J; Pelletier J
    Nat Chem Biol; 2006 Apr; 2(4):213-20. PubMed ID: 16532013
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mapping the interaction between eukaryotic initiation factor 4A (eIF4A) and the inhibitor hippuristanol using carbene footprinting and mass spectrometry.
    Lloyd JR; Hogan A; Paschalis V; Bellamy-Carter J; Bottley A; Seymour GB; Hayes CJ; Oldham NJ
    Proteomics; 2021 Nov; 21(21-22):e2000288. PubMed ID: 34028182
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A comparative study of small molecules targeting eIF4A.
    Naineni SK; Itoua Maïga R; Cencic R; Putnam AA; Amador LA; Rodriguez AD; Jankowsky E; Pelletier J
    RNA; 2020 May; 26(5):541-549. PubMed ID: 32014999
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selective targeting of the DEAD-box RNA helicase eukaryotic initiation factor (eIF) 4A by natural products.
    Shen L; Pelletier J
    Nat Prod Rep; 2020 May; 37(5):609-616. PubMed ID: 31782447
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5' leader regions.
    Steinberger J; Shen L; J Kiniry S; Naineni SK; Cencic R; Amiri M; Aboushawareb SAE; Chu J; Maïga RI; Yachnin BJ; Robert F; Sonenberg N; Baranov PV; Pelletier J
    Nucleic Acids Res; 2020 Sep; 48(17):9521-9537. PubMed ID: 32766783
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting the eIF4A RNA helicase as an anti-neoplastic approach.
    Chu J; Pelletier J
    Biochim Biophys Acta; 2015 Jul; 1849(7):781-91. PubMed ID: 25234619
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modifying chemotherapy response by targeted inhibition of eukaryotic initiation factor 4A.
    Cencic R; Robert F; Galicia-Vázquez G; Malina A; Ravindar K; Somaiah R; Pierre P; Tanaka J; Deslongchamps P; Pelletier J
    Blood Cancer J; 2013 Jul; 3(7):e128. PubMed ID: 23872707
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel Bcr-Abl-mTOR-eIF4A axis regulates IRES-mediated translation of LEF-1.
    Tsai BP; Jimenez J; Lim S; Fitzgerald KD; Zhang M; Chuah CT; Axelrod H; Wilson L; Ong ST; Semler BL; Waterman ML
    Open Biol; 2014 Nov; 4(11):140180. PubMed ID: 25392452
    [TBL] [Abstract][Full Text] [Related]  

  • 10. eIF4B stimulates translation of long mRNAs with structured 5' UTRs and low closed-loop potential but weak dependence on eIF4G.
    Sen ND; Zhou F; Harris MS; Ingolia NT; Hinnebusch AG
    Proc Natl Acad Sci U S A; 2016 Sep; 113(38):10464-72. PubMed ID: 27601676
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CRISPR-Mediated Drug-Target Validation Reveals Selective Pharmacological Inhibition of the RNA Helicase, eIF4A.
    Chu J; Galicia-Vázquez G; Cencic R; Mills JR; Katigbak A; Porco JA; Pelletier J
    Cell Rep; 2016 Jun; 15(11):2340-7. PubMed ID: 27239032
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibitors of translation initiation as cancer therapeutics.
    Lindqvist L; Pelletier J
    Future Med Chem; 2009 Dec; 1(9):1709-22. PubMed ID: 21425987
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of hippuristanol, an inhibitor of eIF4A, on adult T-cell leukemia.
    Tsumuraya T; Ishikawa C; Machijima Y; Nakachi S; Senba M; Tanaka J; Mori N
    Biochem Pharmacol; 2011 Mar; 81(6):713-22. PubMed ID: 21219881
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RNA-mediated sequestration of the RNA helicase eIF4A by Pateamine A inhibits translation initiation.
    Bordeleau ME; Cencic R; Lindqvist L; Oberer M; Northcote P; Wagner G; Pelletier J
    Chem Biol; 2006 Dec; 13(12):1287-95. PubMed ID: 17185224
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery and Characterization of a Eukaryotic Initiation Factor 4A-3-Selective Inhibitor That Suppresses Nonsense-Mediated mRNA Decay.
    Iwatani-Yoshihara M; Ito M; Ishibashi Y; Oki H; Tanaka T; Morishita D; Ito T; Kimura H; Imaeda Y; Aparicio S; Nakanishi A; Kawamoto T
    ACS Chem Biol; 2017 Jul; 12(7):1760-1768. PubMed ID: 28440616
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterisation of the biological response of Saccharomyces cerevisiae to the loss of an allele of the eukaryotic initiation factor 4A.
    Venturi V; Little R; Bircham PW; Rodigheri Brito J; Atkinson PH; Maass DR; Teesdale-Spittle PH
    Biochem Biophys Res Commun; 2018 Feb; 496(4):1082-1087. PubMed ID: 29397069
    [TBL] [Abstract][Full Text] [Related]  

  • 17. FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation.
    Nguyen TM; Kabotyanski EB; Dou Y; Reineke LC; Zhang P; Zhang XH; Malovannaya A; Jung SY; Mo Q; Roarty KP; Chen Y; Zhang B; Neilson JR; Lloyd RE; Perou CM; Ellis MJ; Rosen JM
    Cancer Res; 2018 Aug; 78(15):4229-4240. PubMed ID: 29844125
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Eukaryotic Translation Initiation Factor 4A Down-Regulation Mediates Interleukin-24-Induced Apoptosis through Inhibition of Translation.
    Zhong X; Persaud L; Muharam H; Francis A; Das D; Aktas BH; Sauane M
    Cancers (Basel); 2018 May; 10(5):. PubMed ID: 29786657
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The steroid derivative 6-aminocholestanol inhibits the DEAD-box helicase eIF4A (LieIF4A) from the Trypanosomatid parasite Leishmania by perturbing the RNA and ATP binding sites.
    Abdelkrim YZ; Harigua-Souiai E; Barhoumi M; Banroques J; Blondel A; Guizani I; Tanner NK
    Mol Biochem Parasitol; 2018 Dec; 226():9-19. PubMed ID: 30365976
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation.
    Bordeleau ME; Matthews J; Wojnar JM; Lindqvist L; Novac O; Jankowsky E; Sonenberg N; Northcote P; Teesdale-Spittle P; Pelletier J
    Proc Natl Acad Sci U S A; 2005 Jul; 102(30):10460-5. PubMed ID: 16030146
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.