These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 27339427)

  • 1. Allosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2.
    Janeček M; Rossmann M; Sharma P; Emery A; Huggins DJ; Stockwell SR; Stokes JE; Tan YS; Almeida EG; Hardwick B; Narvaez AJ; Hyvönen M; Spring DR; McKenzie GJ; Venkitaraman AR
    Sci Rep; 2016 Jun; 6():28528. PubMed ID: 27339427
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bcl2l10, a new Tpx2 binding partner, is a master regulator of Aurora kinase A in mouse oocytes.
    Lee SY; Kim EY; Kim KH; Lee KA
    Cell Cycle; 2016 Dec; 15(23):3296-3305. PubMed ID: 27753540
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Spatial regulation of Aurora A activity during mitotic spindle assembly requires RHAMM to correctly localize TPX2.
    Chen H; Mohan P; Jiang J; Nemirovsky O; He D; Fleisch MC; Niederacher D; Pilarski LM; Lim CJ; Maxwell CA
    Cell Cycle; 2014; 13(14):2248-61. PubMed ID: 24875404
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Taxane-mediated radiosensitization derives from chromosomal missegregation on tripolar mitotic spindles orchestrated by AURKA and TPX2.
    Orth M; Unger K; Schoetz U; Belka C; Lauber K
    Oncogene; 2018 Jan; 37(1):52-62. PubMed ID: 28869599
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel mechanism for activation of the protein kinase Aurora A.
    Eyers PA; Erikson E; Chen LG; Maller JL
    Curr Biol; 2003 Apr; 13(8):691-7. PubMed ID: 12699628
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ran modulates spindle assembly by regulating a subset of TPX2 and Kid activities including Aurora A activation.
    Trieselmann N; Armstrong S; Rauw J; Wilde A
    J Cell Sci; 2003 Dec; 116(Pt 23):4791-8. PubMed ID: 14600264
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of N-benzylbenzamide-based allosteric inhibitors of Aurora kinase A.
    Lee H; Kim E; Hwang N; Yoo J; Nam Y; Hwang I; Park JG; Park SE; Chung KS; Won Chung H; Song C; Ji MJ; Park HM; Lee IK; Lee KT; Joo Roh E; Hur W
    Bioorg Med Chem; 2024 Mar; 102():117658. PubMed ID: 38460487
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular mechanism of Aurora A kinase autophosphorylation and its allosteric activation by TPX2.
    Zorba A; Buosi V; Kutter S; Kern N; Pontiggia F; Cho YJ; Kern D
    Elife; 2014 May; 3():e02667. PubMed ID: 24867643
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Aurora A phosphorylation of WD40-repeat protein 62 in mitotic spindle regulation.
    Lim NR; Yeap YY; Ang CS; Williamson NA; Bogoyevitch MA; Quinn LM; Ng DC
    Cell Cycle; 2016; 15(3):413-24. PubMed ID: 26713495
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human TPX2 is required for targeting Aurora-A kinase to the spindle.
    Kufer TA; Silljé HH; Körner R; Gruss OJ; Meraldi P; Nigg EA
    J Cell Biol; 2002 Aug; 158(4):617-23. PubMed ID: 12177045
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of small molecule inhibitors of the Aurora-A/TPX2 complex.
    Asteriti IA; Daidone F; Colotti G; Rinaldo S; Lavia P; Guarguaglini G; Paiardini A
    Oncotarget; 2017 May; 8(19):32117-32133. PubMed ID: 28389630
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
    McIntyre PJ; Collins PM; Vrzal L; Birchall K; Arnold LH; Mpamhanga C; Coombs PJ; Burgess SG; Richards MW; Winter A; Veverka V; Delft FV; Merritt A; Bayliss R
    ACS Chem Biol; 2017 Nov; 12(11):2906-2914. PubMed ID: 29045126
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Determinants for Aurora-A activation and Aurora-B discrimination by TPX2.
    Bayliss R; Sardon T; Ebert J; Lindner D; Vernos I; Conti E
    Cell Cycle; 2004 Apr; 3(4):404-7. PubMed ID: 14752279
    [TBL] [Abstract][Full Text] [Related]  

  • 14. AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation.
    Asteriti IA; Polverino F; Stagni V; Sterbini V; Ascanelli C; Naso FD; Mastrangelo A; Rosa A; Paiardini A; Lindon C; Guarguaglini G
    Life Sci Alliance; 2023 May; 6(5):. PubMed ID: 36797043
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of Xenopus Aurora A activation by TPX2.
    Eyers PA; Maller JL
    J Biol Chem; 2004 Mar; 279(10):9008-15. PubMed ID: 14701852
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Allosteric Targeting of Aurora A Kinase Using Small Molecules: A Step Forward Towards Next Generation Medicines?
    Panicker RC; Coyne AG; Srinivasan R
    Curr Med Chem; 2019; 26(13):2234-2242. PubMed ID: 28748768
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Contribution of AurkA/TPX2 Overexpression to Chromosomal Imbalances and Cancer.
    Polverino F; Mastrangelo A; Guarguaglini G
    Cells; 2024 Aug; 13(16):. PubMed ID: 39195284
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Potential involvement of RITA in the activation of Aurora A at spindle poles during mitosis.
    Kreis NN; Steinhäuser K; Ritter A; Klöble P; Hoock SC; Roth S; Louwen F; Oswald F; Yuan J
    Oncogene; 2019 May; 38(22):4199-4214. PubMed ID: 30705408
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural basis for the design of allosteric inhibitors of the Aurora kinase A enzyme in the cancer chemotherapy.
    de Souza VB; Kawano DF
    Biochim Biophys Acta Gen Subj; 2020 Jan; 1864(1):129448. PubMed ID: 31676293
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The AURKA/TPX2 axis drives colon tumorigenesis cooperatively with MYC.
    Takahashi Y; Sheridan P; Niida A; Sawada G; Uchi R; Mizuno H; Kurashige J; Sugimachi K; Sasaki S; Shimada Y; Hase K; Kusunoki M; Kudo S; Watanabe M; Yamada K; Sugihara K; Yamamoto H; Suzuki A; Doki Y; Miyano S; Mori M; Mimori K
    Ann Oncol; 2015 May; 26(5):935-942. PubMed ID: 25632068
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.