These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

455 related articles for article (PubMed ID: 27349387)

  • 1. Efficient elimination of pancreatic cancer stem cells by hedgehog/GLI inhibitor GANT61 in combination with mTOR inhibition.
    Miyazaki Y; Matsubara S; Ding Q; Tsukasa K; Yoshimitsu M; Kosai K; Takao S
    Mol Cancer; 2016 Jun; 15(1):49. PubMed ID: 27349387
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Anti-cell growth and anti-cancer stem cell activities of the non-canonical hedgehog inhibitor GANT61 in triple-negative breast cancer cells.
    Koike Y; Ohta Y; Saitoh W; Yamashita T; Kanomata N; Moriya T; Kurebayashi J
    Breast Cancer; 2017 Sep; 24(5):683-693. PubMed ID: 28144905
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma.
    Graab U; Hahn H; Fulda S
    Oncotarget; 2015 Apr; 6(11):8722-35. PubMed ID: 25749378
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro.
    You M; Varona-Santos J; Singh S; Robbins DJ; Savaraj N; Nguyen DM
    J Thorac Cardiovasc Surg; 2014 Jan; 147(1):508-16. PubMed ID: 24094913
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Anti-cancer stem cell activity of a hedgehog inhibitor GANT61 in estrogen receptor-positive breast cancer cells.
    Kurebayashi J; Koike Y; Ohta Y; Saitoh W; Yamashita T; Kanomata N; Moriya T
    Cancer Sci; 2017 May; 108(5):918-930. PubMed ID: 28211214
    [TBL] [Abstract][Full Text] [Related]  

  • 6. GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft.
    Fu J; Rodova M; Roy SK; Sharma J; Singh KP; Srivastava RK; Shankar S
    Cancer Lett; 2013 Mar; 330(1):22-32. PubMed ID: 23200667
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth.
    Sharma N; Nanta R; Sharma J; Gunewardena S; Singh KP; Shankar S; Srivastava RK
    Oncotarget; 2015 Oct; 6(31):32039-60. PubMed ID: 26451606
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of pancreatic cancer stem cell characteristics by α-Mangostin: Molecular mechanisms involving Sonic hedgehog and Nanog.
    Ma Y; Yu W; Shrivastava A; Srivastava RK; Shankar S
    J Cell Mol Med; 2019 Apr; 23(4):2719-2730. PubMed ID: 30712329
    [TBL] [Abstract][Full Text] [Related]  

  • 9. mTOR inhibitors counteract tamoxifen-induced activation of breast cancer stem cells.
    Karthik GM; Ma R; Lövrot J; Kis LL; Lindh C; Blomquist L; Fredriksson I; Bergh J; Hartman J
    Cancer Lett; 2015 Oct; 367(1):76-87. PubMed ID: 26208432
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sonic hedgehog signaling inhibition provides opportunities for targeted therapy by sulforaphane in regulating pancreatic cancer stem cell self-renewal.
    Rodova M; Fu J; Watkins DN; Srivastava RK; Shankar S
    PLoS One; 2012; 7(9):e46083. PubMed ID: 23029396
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cyclopamine reverts acquired chemoresistance and down-regulates cancer stem cell markers in pancreatic cancer cell lines.
    Yao J; An Y; Wie JS; Ji ZL; Lu ZP; Wu JL; Jiang KR; Chen P; Xu ZK; Miao Y
    Swiss Med Wkly; 2011; 141():w13208. PubMed ID: 21630164
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of hedgehog signaling depresses self-renewal of pancreatic cancer stem cells and reverses chemoresistance.
    Huang FT; Zhuan-Sun YX; Zhuang YY; Wei SL; Tang J; Chen WB; Zhang SN
    Int J Oncol; 2012 Nov; 41(5):1707-14. PubMed ID: 22923052
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Widespread Expression of Hedgehog Pathway Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor Growth by GANT61: Implications for Cancer Therapy.
    Réda J; Vachtenheim J; Vlčková K; Horák P; Vachtenheim J; Ondrušová L
    Int J Mol Sci; 2018 Sep; 19(9):. PubMed ID: 30201866
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, Synthesis and Biological Evaluation of novel Hedgehog Inhibitors for treating Pancreatic Cancer.
    Kumar V; Chaudhary AK; Dong Y; Zhong HA; Mondal G; Lin F; Kumar V; Mahato RI
    Sci Rep; 2017 May; 7(1):1665. PubMed ID: 28490735
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.
    Benvenuto M; Masuelli L; De Smaele E; Fantini M; Mattera R; Cucchi D; Bonanno E; Di Stefano E; Frajese GV; Orlandi A; Screpanti I; Gulino A; Modesti A; Bei R
    Oncotarget; 2016 Feb; 7(8):9250-70. PubMed ID: 26843616
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sanguinarine inhibits pancreatic cancer stem cell characteristics by inducing oxidative stress and suppressing sonic hedgehog-Gli-Nanog pathway.
    Ma Y; Yu W; Shrivastava A; Alemi F; Lankachandra K; Srivastava RK; Shankar S
    Carcinogenesis; 2017 Oct; 38(10):1047-1056. PubMed ID: 28968696
    [TBL] [Abstract][Full Text] [Related]  

  • 17. mTOR plays critical roles in pancreatic cancer stem cells through specific and stemness-related functions.
    Matsubara S; Ding Q; Miyazaki Y; Kuwahata T; Tsukasa K; Takao S
    Sci Rep; 2013 Nov; 3():3230. PubMed ID: 24231729
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel therapeutic strategy targeting the Hedgehog signalling and mTOR pathways in biliary tract cancer.
    Zuo M; Rashid A; Churi C; Vauthey JN; Chang P; Li Y; Hung MC; Li D; Javle M
    Br J Cancer; 2015 Mar; 112(6):1042-51. PubMed ID: 25742482
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hedgehog-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells.
    Santini R; Vinci MC; Pandolfi S; Penachioni JY; Montagnani V; Olivito B; Gattai R; Pimpinelli N; Gerlini G; Borgognoni L; Stecca B
    Stem Cells; 2012 Sep; 30(9):1808-18. PubMed ID: 22730244
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ErbB2 signaling activates the Hedgehog pathway via PI3K-Akt in human esophageal adenocarcinoma: identification of novel targets for concerted therapy concepts.
    Kebenko M; Drenckhan A; Gros SJ; Jücker M; Grabinski N; Ewald F; Grottke A; Schultze A; Izbicki JR; Bokemeyer C; Wellbrock J; Fiedler W
    Cell Signal; 2015 Feb; 27(2):373-81. PubMed ID: 25435423
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.