These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1. Eisele F; Wolf DH FEBS Lett; 2008 Dec; 582(30):4143-6. PubMed ID: 19041308 [TBL] [Abstract][Full Text] [Related]
4. Unconventional secretion of misfolded proteins promotes adaptation to proteasome dysfunction in mammalian cells. Lee JG; Takahama S; Zhang G; Tomarev SI; Ye Y Nat Cell Biol; 2016 Jul; 18(7):765-76. PubMed ID: 27295555 [TBL] [Abstract][Full Text] [Related]
5. ERAD: the long road to destruction. Meusser B; Hirsch C; Jarosch E; Sommer T Nat Cell Biol; 2005 Aug; 7(8):766-72. PubMed ID: 16056268 [TBL] [Abstract][Full Text] [Related]
6. False start: cotranslational protein ubiquitination and cytosolic protein quality control. Comyn SA; Chan GT; Mayor T J Proteomics; 2014 Apr; 100():92-101. PubMed ID: 23954725 [TBL] [Abstract][Full Text] [Related]
7. Hul5 ubiquitin ligase: good riddance to bad proteins. Fang NN; Mayor T Prion; 2012 Jul; 6(3):240-4. PubMed ID: 22561164 [TBL] [Abstract][Full Text] [Related]
8. USP19-Mediated Deubiquitination Facilitates the Stabilization of HRD1 Ubiquitin Ligase. Harada K; Kato M; Nakamura N Int J Mol Sci; 2016 Nov; 17(11):. PubMed ID: 27827840 [TBL] [Abstract][Full Text] [Related]
9. ERAD ubiquitin ligases: multifunctional tools for protein quality control and waste disposal in the endoplasmic reticulum. Mehnert M; Sommer T; Jarosch E Bioessays; 2010 Oct; 32(10):905-13. PubMed ID: 20806269 [TBL] [Abstract][Full Text] [Related]
11. Regulation of protein homeostasis by unconventional protein secretion in mammalian cells. Ye Y Semin Cell Dev Biol; 2018 Nov; 83():29-35. PubMed ID: 29549062 [TBL] [Abstract][Full Text] [Related]
12. MPSR1 is a cytoplasmic PQC E3 ligase for eliminating emergent misfolded proteins in Kim JH; Cho SK; Oh TR; Ryu MY; Yang SW; Kim WT Proc Natl Acad Sci U S A; 2017 Nov; 114(46):E10009-E10017. PubMed ID: 29087340 [TBL] [Abstract][Full Text] [Related]
13. Molecular mass as a determinant for nuclear San1-dependent targeting of misfolded cytosolic proteins to proteasomal degradation. Amm I; Wolf DH FEBS Lett; 2016 Jun; 590(12):1765-75. PubMed ID: 27173001 [TBL] [Abstract][Full Text] [Related]
14. A stalled retrotranslocation complex reveals physical linkage between substrate recognition and proteasomal degradation during ER-associated degradation. Nakatsukasa K; Brodsky JL; Kamura T Mol Biol Cell; 2013 Jun; 24(11):1765-75, S1-8. PubMed ID: 23536702 [TBL] [Abstract][Full Text] [Related]
15. Hsp70 targets a cytoplasmic quality control substrate to the San1p ubiquitin ligase. Guerriero CJ; Weiberth KF; Brodsky JL J Biol Chem; 2013 Jun; 288(25):18506-20. PubMed ID: 23653356 [TBL] [Abstract][Full Text] [Related]
16. Deubiquitinase activity is required for the proteasomal degradation of misfolded cytosolic proteins upon heat-stress. Fang NN; Zhu M; Rose A; Wu KP; Mayor T Nat Commun; 2016 Oct; 7():12907. PubMed ID: 27698423 [TBL] [Abstract][Full Text] [Related]
17. The Type II Hsp40 Sis1 cooperates with Hsp70 and the E3 ligase Ubr1 to promote degradation of terminally misfolded cytosolic protein. Summers DW; Wolfe KJ; Ren HY; Cyr DM PLoS One; 2013; 8(1):e52099. PubMed ID: 23341891 [TBL] [Abstract][Full Text] [Related]
18. E6-AP promotes misfolded polyglutamine proteins for proteasomal degradation and suppresses polyglutamine protein aggregation and toxicity. Mishra A; Dikshit P; Purkayastha S; Sharma J; Nukina N; Jana NR J Biol Chem; 2008 Mar; 283(12):7648-56. PubMed ID: 18201976 [TBL] [Abstract][Full Text] [Related]
19. Ubiquitin ligase Hul5 is required for fragment-specific substrate degradation in endoplasmic reticulum-associated degradation. Kohlmann S; Schäfer A; Wolf DH J Biol Chem; 2008 Jun; 283(24):16374-83. PubMed ID: 18436532 [TBL] [Abstract][Full Text] [Related]
20. Regulation of the cytoplasmic quality control protein degradation pathway by BAG2. Dai Q; Qian SB; Li HH; McDonough H; Borchers C; Huang D; Takayama S; Younger JM; Ren HY; Cyr DM; Patterson C J Biol Chem; 2005 Nov; 280(46):38673-81. PubMed ID: 16169850 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]