BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 27351228)

  • 1. Characterization of a P-Rex1 gene signature in breast cancer cells.
    Barrio-Real L; Wertheimer E; Garg R; Abba MC; Kazanietz MG
    Oncotarget; 2016 Aug; 7(32):51335-51348. PubMed ID: 27351228
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Heregulin/ErbB3 Signaling Enhances CXCR4-Driven Rac1 Activation and Breast Cancer Cell Motility via Hypoxia-Inducible Factor 1α.
    Lopez-Haber C; Barrio-Real L; Casado-Medrano V; Kazanietz MG
    Mol Cell Biol; 2016 Aug; 36(15):2011-26. PubMed ID: 27185877
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation.
    Barrio-Real L; Benedetti LG; Engel N; Tu Y; Cho S; Sukumar S; Kazanietz MG
    Breast Cancer Res; 2014 Sep; 16(5):441. PubMed ID: 25248717
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphorylation of P-Rex1 at serine 1169 participates in IGF-1R signaling in breast cancer cells.
    Montero JC; Seoane S; Pandiella A
    Cell Signal; 2013 Nov; 25(11):2281-9. PubMed ID: 23899556
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer.
    Sosa MS; Lopez-Haber C; Yang C; Wang H; Lemmon MA; Busillo JM; Luo J; Benovic JL; Klein-Szanto A; Yagi H; Gutkind JS; Parsons RE; Kazanietz MG
    Mol Cell; 2010 Dec; 40(6):877-92. PubMed ID: 21172654
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rac signaling in breast cancer: a tale of GEFs and GAPs.
    Wertheimer E; Gutierrez-Uzquiza A; Rosemblit C; Lopez-Haber C; Sosa MS; Kazanietz MG
    Cell Signal; 2012 Feb; 24(2):353-362. PubMed ID: 21893191
    [TBL] [Abstract][Full Text] [Related]  

  • 7. P-Rex1 is dispensable for Erk activation and mitogenesis in breast cancer.
    Barrio-Real L; Lopez-Haber C; Casado-Medrano V; Goglia AG; Toettcher JE; Caloca MJ; Kazanietz MG
    Oncotarget; 2018 Jun; 9(47):28612-28624. PubMed ID: 29983884
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Heregulin beta1 promotes breast cancer cell proliferation through Rac/ERK-dependent induction of cyclin D1 and p21Cip1.
    Yang C; Klein EA; Assoian RK; Kazanietz MG
    Biochem J; 2008 Feb; 410(1):167-75. PubMed ID: 17941827
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Essential role for Rac in heregulin beta1 mitogenic signaling: a mechanism that involves epidermal growth factor receptor and is independent of ErbB4.
    Yang C; Liu Y; Lemmon MA; Kazanietz MG
    Mol Cell Biol; 2006 Feb; 26(3):831-42. PubMed ID: 16428439
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cucurbitacin I inhibits Rac1 activation in breast cancer cells by a reactive oxygen species-mediated mechanism and independently of Janus tyrosine kinase 2 and P-Rex1.
    Lopez-Haber C; Kazanietz MG
    Mol Pharmacol; 2013 May; 83(5):1141-54. PubMed ID: 23478800
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The P-Rex1/Rac signaling pathway as a point of convergence for HER/ErbB receptor and GPCR responses.
    Kazanietz MG; Barrio-Real L; Casado-Medrano V; Baker MJ; Lopez-Haber C
    Small GTPases; 2018 Jul; 9(4):297-303. PubMed ID: 27588611
    [TBL] [Abstract][Full Text] [Related]  

  • 12. P-Rex1 participates in Neuregulin-ErbB signal transduction and its expression correlates with patient outcome in breast cancer.
    Montero JC; Seoane S; Ocaña A; Pandiella A
    Oncogene; 2011 Mar; 30(9):1059-71. PubMed ID: 21042280
    [TBL] [Abstract][Full Text] [Related]  

  • 13. P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils.
    Damoulakis G; Gambardella L; Rossman KL; Lawson CD; Anderson KE; Fukui Y; Welch HC; Der CJ; Stephens LR; Hawkins PT
    J Cell Sci; 2014 Jun; 127(Pt 11):2589-600. PubMed ID: 24659802
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PtdIns(3,4,5)P
    Srijakotre N; Liu HJ; Nobis M; Man J; Yip HYK; Papa A; Abud HE; Anderson KI; Welch HCE; Tiganis T; Timpson P; McLean CA; Ooms LM; Mitchell CA
    Proc Natl Acad Sci U S A; 2020 Nov; 117(45):28056-28067. PubMed ID: 33097662
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion.
    Zrihan-Licht S; Fu Y; Settleman J; Schinkmann K; Shaw L; Keydar I; Avraham S; Avraham H
    Oncogene; 2000 Mar; 19(10):1318-28. PubMed ID: 10713673
    [TBL] [Abstract][Full Text] [Related]  

  • 16. P-Rex1 is a primary Rac2 guanine nucleotide exchange factor in mouse neutrophils.
    Dong X; Mo Z; Bokoch G; Guo C; Li Z; Wu D
    Curr Biol; 2005 Oct; 15(20):1874-9. PubMed ID: 16243036
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis.
    Qin J; Xie Y; Wang B; Hoshino M; Wolff DW; Zhao J; Scofield MA; Dowd FJ; Lin MF; Tu Y
    Oncogene; 2009 Apr; 28(16):1853-63. PubMed ID: 19305425
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Up-regulation of vascular endothelial growth factor in breast cancer cells by the heregulin-beta1-activated p38 signaling pathway enhances endothelial cell migration.
    Xiong S; Grijalva R; Zhang L; Nguyen NT; Pisters PW; Pollock RE; Yu D
    Cancer Res; 2001 Feb; 61(4):1727-32. PubMed ID: 11245489
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Heregulin beta1-activated phosphatidylinositol 3-kinase enhances aggregation of MCF-7 breast cancer cells independent of extracellular signal-regulated kinase.
    Tan M; Grijalva R; Yu D
    Cancer Res; 1999 Apr; 59(7):1620-5. PubMed ID: 10197638
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Rho guanine nucleotide exchange factor P-Rex1 as a potential drug target for cancer metastasis and inflammatory diseases.
    Ye RD
    Pharmacol Res; 2020 Mar; 153():104676. PubMed ID: 32006571
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.