109 related articles for article (PubMed ID: 27354635)
1. An Antitumor 2-Hydroxyarylidene-4-cyclopentene-1,3-Dione as a Protein Tyrosine Kinase Inhibitor: Interaction Between TX-1123 Derivatives and Src Kinase.
Ohkura K; Kawaguchi Y; Tatematsu Y; Uto Y; Hori H
Anticancer Res; 2016 Jul; 36(7):3645-9. PubMed ID: 27354635
[TBL] [Abstract][Full Text] [Related]
2. TX-1123: an antitumor 2-hydroxyarylidene-4-cyclopentene-1,3-dione as a protein tyrosine kinase inhibitor having low mitochondrial toxicity.
Hori H; Nagasawa H; Ishibashi M; Uto Y; Hirata A; Saijo K; Ohkura K; Kirk KL; Uehara Y
Bioorg Med Chem; 2002 Oct; 10(10):3257-65. PubMed ID: 12150871
[TBL] [Abstract][Full Text] [Related]
3. Design of hypoxia-targeting protein tyrosine kinase inhibitor using an innovative pharmacophore 2-methylene-4-cyclopentene-1,3-dione.
Hori H; Nagasawa H; Uto Y; Ohkura K; Kirk KL; Uehara Y; Shimamura M
Biochim Biophys Acta; 2004 Mar; 1697(1-2):29-38. PubMed ID: 15023348
[TBL] [Abstract][Full Text] [Related]
4. Interactive Analysis of TX-1123 with Cyclo-oxygenase: Design of COX2 Selective TX Analogs.
Ohkura K; Tatematsu Y; Kawaguchi Y; Uto Y; Hori H
Anticancer Res; 2017 Jul; 37(7):3849-3854. PubMed ID: 28668885
[TBL] [Abstract][Full Text] [Related]
5. PH006, a novel and selective Src kinase inhibitor, suppresses human breast cancer growth and metastasis in vitro and in vivo.
Ma JG; Huang H; Chen SM; Chen Y; Xin XL; Lin LP; Ding J; Liu H; Meng LH
Breast Cancer Res Treat; 2011 Nov; 130(1):85-96. PubMed ID: 21181437
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and evaluation of acridine derivatives as multi-target Src and MEK kinase inhibitors for anti-tumor treatment.
Cui Z; Li X; Li L; Zhang B; Gao C; Chen Y; Tan C; Liu H; Xie W; Yang T; Jiang Y
Bioorg Med Chem; 2016 Jan; 24(2):261-9. PubMed ID: 26707846
[TBL] [Abstract][Full Text] [Related]
7. Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds.
Dalgarno D; Stehle T; Narula S; Schelling P; van Schravendijk MR; Adams S; Andrade L; Keats J; Ram M; Jin L; Grossman T; MacNeil I; Metcalf C; Shakespeare W; Wang Y; Keenan T; Sundaramoorthi R; Bohacek R; Weigele M; Sawyer T
Chem Biol Drug Des; 2006 Jan; 67(1):46-57. PubMed ID: 16492148
[TBL] [Abstract][Full Text] [Related]
8. 4-Aryl-4H-chromene-3-carbonitrile derivatives: evaluation of Src kinase inhibitory and anticancer activities.
Fallah-Tafti A; Tiwari R; Shirazi AN; Akbarzadeh T; Mandal D; Shafiee A; Parang K; Foroumadi A
Med Chem; 2011 Sep; 7(5):466-72. PubMed ID: 21801146
[TBL] [Abstract][Full Text] [Related]
9. Discovery of 4,6-substituted-(diaphenylamino)quinazolines as potent c-Src inhibitors.
Li JR; Li DD; Fang F; Du QR; Lin L; Sun J; Qian Y; Zhu HL
Org Biomol Chem; 2013 Dec; 11(48):8375-86. PubMed ID: 24178241
[TBL] [Abstract][Full Text] [Related]
10. Discovery of novel purine derivatives with potent and selective inhibitory activity against c-Src tyrosine kinase.
Huang H; Ma J; Shi J; Meng L; Jiang H; Ding J; Liu H
Bioorg Med Chem; 2010 Jul; 18(13):4615-24. PubMed ID: 20570525
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and anti-tyrosine kinase activity of 3-(substituted-benzylidene)-1, 3-dihydro-indolin derivatives: investigation of their role against p60c-Src receptor tyrosine kinase with the application of receptor docking studies.
Olgen S; Akaho E; Nebioglu D
Farmaco; 2005; 60(6-7):497-506. PubMed ID: 15927182
[TBL] [Abstract][Full Text] [Related]
12. Design of antiangiogenic hypoxic cell radiosensitizers: 2-nitroimidazoles containing a 2-aminomethylene-4-cyclopentene-1,3-dione moiety.
Uto Y; Nagasawa H; Jin CZ; Nakayama S; Tanaka A; Kiyoi S; Nakashima H; Shimamura M; Inayama S; Fujiwara T; Takeuchi Y; Uehara Y; Kirk KL; Nakata E; Hori H
Bioorg Med Chem; 2008 Jun; 16(11):6042-53. PubMed ID: 18474428
[TBL] [Abstract][Full Text] [Related]
13. Structure-based virtual screening of Src kinase inhibitors.
Lee K; Kim J; Jeong KW; Lee KW; Lee Y; Song JY; Kim MS; Lee GS; Kim Y
Bioorg Med Chem; 2009 Apr; 17(8):3152-61. PubMed ID: 19321350
[TBL] [Abstract][Full Text] [Related]
14. Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells.
Radi M; Brullo C; Crespan E; Tintori C; Musumeci F; Biava M; Schenone S; Dreassi E; Zamperini C; Maga G; Pagano D; Angelucci A; Bologna M; Botta M
Bioorg Med Chem Lett; 2011 Oct; 21(19):5928-33. PubMed ID: 21856155
[TBL] [Abstract][Full Text] [Related]
15. Novel heterocyclic-fused pyrimidine derivatives: synthesis, molecular modeling and pharmacological screening.
Arafa RK; Nour MS; El-Sayed NA
Eur J Med Chem; 2013 Nov; 69():498-507. PubMed ID: 24090920
[TBL] [Abstract][Full Text] [Related]
16. Design, Synthesis, and Structure-Activity Relationship Studies of 3-(Phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Derivatives as a New Class of Src Inhibitors with Potent Activities in Models of Triple Negative Breast Cancer.
Zhang CH; Zheng MW; Li YP; Lin XD; Huang M; Zhong L; Li GB; Zhang RJ; Lin WT; Jiao Y; Wu XA; Yang J; Xiang R; Chen LJ; Zhao YL; Cheng W; Wei YQ; Yang SY
J Med Chem; 2015 May; 58(9):3957-74. PubMed ID: 25835317
[TBL] [Abstract][Full Text] [Related]
17. Identification of Aminoimidazole and Aminothiazole Derivatives as Src Family Kinase Inhibitors.
Francini CM; Fallacara AL; Artusi R; Mennuni L; Calgani A; Angelucci A; Schenone S; Botta M
ChemMedChem; 2015 Dec; 10(12):2027-41. PubMed ID: 26514807
[TBL] [Abstract][Full Text] [Related]
18. Structural basis for the inhibitor recognition of human Lyn kinase domain.
Miyano N; Kinoshita T; Nakai R; Kirii Y; Yokota K; Tada T
Bioorg Med Chem Lett; 2009 Dec; 19(23):6557-60. PubMed ID: 19857964
[TBL] [Abstract][Full Text] [Related]
19. 4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonitriles as potent Src kinase inhibitors.
Berger DM; Dutia M; Birnberg G; Powell D; Boschelli DH; Wang YD; Ravi M; Yaczko D; Golas J; Lucas J; Boschelli F
J Med Chem; 2005 Sep; 48(19):5909-20. PubMed ID: 16161995
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and evaluation of c-Src kinase inhibitory activity of pyridin-2(1H)-one derivatives.
Chand K; Prasad S; Tiwari RK; Shirazi AN; Kumar S; Parang K; Sharma SK
Bioorg Chem; 2014 Apr; 53():75-82. PubMed ID: 24632506
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
