These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
172 related articles for article (PubMed ID: 27355874)
1. Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging. Liang SH; Chen JM; Normandin MD; Chang JS; Chang GC; Taylor CK; Trapa P; Plummer MS; Para KS; Conn EL; Lopresti-Morrow L; Lanyon LF; Cook JM; Richter KE; Nolan CE; Schachter JB; Janat F; Che Y; Shanmugasundaram V; Lefker BA; Enerson BE; Livni E; Wang L; Guehl NJ; Patnaik D; Wagner FF; Perlis R; Holson EB; Haggarty SJ; El Fakhri G; Kurumbail RG; Vasdev N Angew Chem Int Ed Engl; 2016 Aug; 55(33):9601-5. PubMed ID: 27355874 [TBL] [Abstract][Full Text] [Related]
2. Structural Basis for Achieving GSK-3β Inhibition with High Potency, Selectivity, and Brain Exposure for Positron Emission Tomography Imaging and Drug Discovery. Bernard-Gauthier V; Mossine AV; Knight A; Patnaik D; Zhao WN; Cheng C; Krishnan HS; Xuan LL; Chindavong PS; Reis SA; Chen JM; Shao X; Stauff J; Arteaga J; Sherman P; Salem N; Bonsall D; Amaral B; Varlow C; Wells L; Martarello L; Patel S; Liang SH; Kurumbail RG; Haggarty SJ; Scott PJH; Vasdev N J Med Chem; 2019 Nov; 62(21):9600-9617. PubMed ID: 31535859 [TBL] [Abstract][Full Text] [Related]
3. 5-Aryl-4-carboxamide-1,3-oxazoles: potent and selective GSK-3 inhibitors. Gentile G; Merlo G; Pozzan A; Bernasconi G; Bax B; Bamborough P; Bridges A; Carter P; Neu M; Yao G; Brough C; Cutler G; Coffin A; Belyanskaya S Bioorg Med Chem Lett; 2012 Mar; 22(5):1989-94. PubMed ID: 22310227 [TBL] [Abstract][Full Text] [Related]
4. Synthesis and evaluation of 8-amino-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives as glycogen synthase kinase-3 (GSK-3) inhibitors. Chun K; Park JS; Lee HC; Kim YH; Ye IH; Kim KJ; Ku IW; Noh MY; Cho GW; Kim H; Kim SH; Kim J Bioorg Med Chem Lett; 2013 Jul; 23(13):3983-7. PubMed ID: 23683591 [TBL] [Abstract][Full Text] [Related]
6. Efficacy of a novel, orally active GSK-3 inhibitor 6-Methyl-N-[3-[[3-(1-methylethoxy)propyl]carbamoyl]-1H-pyrazol-4-yl]pyridine-3-carboxamide in tau transgenic mice. Uno Y; Iwashita H; Tsukamoto T; Uchiyama N; Kawamoto T; Kori M; Nakanishi A Brain Res; 2009 Nov; 1296():148-63. PubMed ID: 19698704 [TBL] [Abstract][Full Text] [Related]
7. The mood stabilizing properties of AF3581, a novel potent GSK-3β inhibitor. Capurro V; Lanfranco M; Summa M; Porceddu PF; Ciampoli M; Margaroli N; Durando L; Garrone B; Ombrato R; Tongiani S; Reggiani A Biomed Pharmacother; 2020 Aug; 128():110249. PubMed ID: 32470749 [TBL] [Abstract][Full Text] [Related]
8. Synthesis and evaluation of [(11)C]PyrATP-1, a novel radiotracer for PET imaging of glycogen synthase kinase-3β (GSK-3β). Cole EL; Shao X; Sherman P; Quesada C; Fawaz MV; Desmond TJ; Scott PJ Nucl Med Biol; 2014 Jul; 41(6):507-12. PubMed ID: 24768148 [TBL] [Abstract][Full Text] [Related]
9. Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors. Gandini A; Bartolini M; Tedesco D; Martinez-Gonzalez L; Roca C; Campillo NE; Zaldivar-Diez J; Perez C; Zuccheri G; Miti A; Feoli A; Castellano S; Petralla S; Monti B; Rossi M; Moda F; Legname G; Martinez A; Bolognesi ML J Med Chem; 2018 Sep; 61(17):7640-7656. PubMed ID: 30078314 [TBL] [Abstract][Full Text] [Related]
10. A novel glycogen synthase kinase-3 inhibitor 2-methyl-5-(3-{4-[(S )-methylsulfinyl]phenyl}-1-benzofuran-5-yl)-1,3,4-oxadiazole decreases tau phosphorylation and ameliorates cognitive deficits in a transgenic model of Alzheimer's disease. Onishi T; Iwashita H; Uno Y; Kunitomo J; Saitoh M; Kimura E; Fujita H; Uchiyama N; Kori M; Takizawa M J Neurochem; 2011 Dec; 119(6):1330-40. PubMed ID: 21992552 [TBL] [Abstract][Full Text] [Related]
11. Synthesis of pyrimidin-4-one-1,2,3-triazole conjugates as glycogen synthase kinase-3β inhibitors with anti-depressant activity. Khan I; Tantray MA; Hamid H; Alam MS; Kalam A; Hussain F; Dhulap A Bioorg Chem; 2016 Oct; 68():41-55. PubMed ID: 27454617 [TBL] [Abstract][Full Text] [Related]
12. Discovery of Isonicotinamides as Highly Selective, Brain Penetrable, and Orally Active Glycogen Synthase Kinase-3 Inhibitors. Luo G; Chen L; Burton CR; Xiao H; Sivaprakasam P; Krause CM; Cao Y; Liu N; Lippy J; Clarke WJ; Snow K; Raybon J; Arora V; Pokross M; Kish K; Lewis HA; Langley DR; Macor JE; Dubowchik GM J Med Chem; 2016 Feb; 59(3):1041-51. PubMed ID: 26751161 [TBL] [Abstract][Full Text] [Related]
13. The first synthesis of [(11)C]SB-216763, a new potential PET agent for imaging of glycogen synthase kinase-3 (GSK-3). Wang M; Gao M; Miller KD; Sledge GW; Hutchins GD; Zheng QH Bioorg Med Chem Lett; 2011 Jan; 21(1):245-9. PubMed ID: 21115250 [TBL] [Abstract][Full Text] [Related]
14. 2-(2-Phenylmorpholin-4-yl)pyrimidin-4(3H)-ones; a new class of potent, selective and orally active glycogen synthase kinase-3β inhibitors. Fukunaga K; Uehara F; Aritomo K; Shoda A; Hiki S; Okuyama M; Usui Y; Watanabe K; Yamakoshi K; Kohara T; Hanano T; Tanaka H; Tsuchiya S; Sunada S; Saito K; Eguchi J; Yuki S; Asano S; Tanaka S; Mori A; Yamagami K; Baba H; Horikawa T; Fujimura M Bioorg Med Chem Lett; 2013 Dec; 23(24):6933-7. PubMed ID: 24176395 [TBL] [Abstract][Full Text] [Related]
15. Mechanism of zinc-induced phosphorylation of p70 S6 kinase and glycogen synthase kinase 3beta in SH-SY5Y neuroblastoma cells. An WL; Bjorkdahl C; Liu R; Cowburn RF; Winblad B; Pei JJ J Neurochem; 2005 Mar; 92(5):1104-15. PubMed ID: 15715661 [TBL] [Abstract][Full Text] [Related]
16. Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core. Sivaprakasam P; Han X; Civiello RL; Jacutin-Porte S; Kish K; Pokross M; Lewis HA; Ahmed N; Szapiel N; Newitt JA; Baldwin ET; Xiao H; Krause CM; Park H; Nophsker M; Lippy JS; Burton CR; Langley DR; Macor JE; Dubowchik GM Bioorg Med Chem Lett; 2015 May; 25(9):1856-63. PubMed ID: 25845281 [TBL] [Abstract][Full Text] [Related]
17. Inhibition of glycogen synthase kinase-3 reverses tau hyperphosphorylation induced by Pin1 down-regulation. Xiong YS; Wang DL; Tan L; Wang X; Chen LM; Gong CX; Wang JZ; Zhu LQ CNS Neurol Disord Drug Targets; 2013 May; 12(3):436-43. PubMed ID: 23469846 [TBL] [Abstract][Full Text] [Related]
18. Structure-based optimization of oxadiazole-based GSK-3 inhibitors. Lo Monte F; Kramer T; Gu J; Brodrecht M; Pilakowski J; Fuertes A; Dominguez JM; Plotkin B; Eldar-Finkelman H; Schmidt B Eur J Med Chem; 2013 Mar; 61():26-40. PubMed ID: 22749643 [TBL] [Abstract][Full Text] [Related]
19. Efficacy of small-molecule glycogen synthase kinase-3 inhibitors in the postnatal rat model of tau hyperphosphorylation. Selenica ML; Jensen HS; Larsen AK; Pedersen ML; Helboe L; Leist M; Lotharius J Br J Pharmacol; 2007 Nov; 152(6):959-79. PubMed ID: 17906685 [TBL] [Abstract][Full Text] [Related]
20. Discovery of 2-(Anilino)pyrimidine-4-carboxamides as Highly Potent, Selective, and Orally Active Glycogen Synthase Kinase-3 (GSK-3) Inhibitors. Hartz RA; Ahuja VT; Luo G; Chen L; Sivaprakasam P; Xiao H; Krause CM; Clarke WJ; Xu S; Tokarski JS; Kish K; Lewis H; Szapiel N; Ravirala R; Mutalik S; Nakmode D; Shah D; Burton CR; Macor JE; Dubowchik GM J Med Chem; 2023 Jun; 66(11):7534-7552. PubMed ID: 37235865 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]