These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

364 related articles for article (PubMed ID: 27362797)

  • 21. Synthetic lethality of combined glutaminase and Hsp90 inhibition in mTORC1-driven tumor cells.
    Li J; Csibi A; Yang S; Hoffman GR; Li C; Zhang E; Yu JJ; Blenis J
    Proc Natl Acad Sci U S A; 2015 Jan; 112(1):E21-9. PubMed ID: 25524627
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin.
    Malhowski AJ; Hira H; Bashiruddin S; Warburton R; Goto J; Robert B; Kwiatkowski DJ; Finlay GA
    Hum Mol Genet; 2011 Apr; 20(7):1290-305. PubMed ID: 21212099
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy.
    Castets P; Lin S; Rion N; Di Fulvio S; Romanino K; Guridi M; Frank S; Tintignac LA; Sinnreich M; Rüegg MA
    Cell Metab; 2013 May; 17(5):731-44. PubMed ID: 23602450
    [TBL] [Abstract][Full Text] [Related]  

  • 24. AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa.
    Xue Y; Wang SK; Rana P; West ER; Hong CM; Feng H; Wu DM; Cepko CL
    Elife; 2021 Apr; 10():. PubMed ID: 33847261
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Loss of Tsc1 accelerates malignant gliomagenesis when combined with oncogenic signals.
    Yamada D; Hoshii T; Tanaka S; Hegazy AM; Kobayashi M; Tadokoro Y; Ohta K; Ueno M; Ali MA; Hirao A
    J Biochem; 2014 Apr; 155(4):227-33. PubMed ID: 24368778
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1.
    Kathage B; Gehlert S; Ulbricht A; Lüdecke L; Tapia VE; Orfanos Z; Wenzel D; Bloch W; Volkmer R; Fleischmann BK; Fürst DO; Höhfeld J
    Biochim Biophys Acta Mol Cell Res; 2017 Jan; 1864(1):62-75. PubMed ID: 27756573
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Selective Tuberous Sclerosis Complex 1 Gene Deletion in Smooth Muscle Activates Mammalian Target of Rapamycin Signaling and Induces Pulmonary Hypertension.
    Houssaini A; Abid S; Derumeaux G; Wan F; Parpaleix A; Rideau D; Marcos E; Kebe K; Czibik G; Sawaki D; Treins C; Dubois-Randé JL; Li Z; Amsellem V; Lipskaia L; Pende M; Adnot S
    Am J Respir Cell Mol Biol; 2016 Sep; 55(3):352-67. PubMed ID: 26991739
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A cell-penetrating ester of the neural metabolite lanthionine ketimine stimulates autophagy through the mTORC1 pathway: Evidence for a mechanism of action with pharmacological implications for neurodegenerative pathologies.
    Harris-White ME; Ferbas KG; Johnson MF; Eslami P; Poteshkina A; Venkova K; Christov A; Hensley K
    Neurobiol Dis; 2015 Dec; 84():60-8. PubMed ID: 25779968
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Role of the sigma-1 receptor chaperone in rod and cone photoreceptor degenerations in a mouse model of retinitis pigmentosa.
    Yang H; Fu Y; Liu X; Shahi PK; Mavlyutov TA; Li J; Yao A; Guo SZ; Pattnaik BR; Guo LW
    Mol Neurodegener; 2017 Sep; 12(1):68. PubMed ID: 28927431
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Resveratrol prevents rapamycin-induced upregulation of autophagy and selectively induces apoptosis in TSC2-deficient cells.
    Alayev A; Sun Y; Snyder RB; Berger SM; Yu JJ; Holz MK
    Cell Cycle; 2014; 13(3):371-82. PubMed ID: 24304514
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Aberrant hyperactivation of akt and Mammalian target of rapamycin complex 1 signaling in sporadic chordomas.
    Han S; Polizzano C; Nielsen GP; Hornicek FJ; Rosenberg AE; Ramesh V
    Clin Cancer Res; 2009 Mar; 15(6):1940-6. PubMed ID: 19276265
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Iron overload inhibits late stage autophagic flux leading to insulin resistance.
    Jahng JWS; Alsaadi RM; Palanivel R; Song E; Hipolito VEB; Sung HK; Botelho RJ; Russell RC; Sweeney G
    EMBO Rep; 2019 Oct; 20(10):e47911. PubMed ID: 31441223
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21.
    Cornu M; Oppliger W; Albert V; Robitaille AM; Trapani F; Quagliata L; Fuhrer T; Sauer U; Terracciano L; Hall MN
    Proc Natl Acad Sci U S A; 2014 Aug; 111(32):11592-9. PubMed ID: 25082895
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Suppression of lysosome function induces autophagy via a feedback down-regulation of MTOR complex 1 (MTORC1) activity.
    Li M; Khambu B; Zhang H; Kang JH; Chen X; Chen D; Vollmer L; Liu PQ; Vogt A; Yin XM
    J Biol Chem; 2013 Dec; 288(50):35769-80. PubMed ID: 24174532
    [TBL] [Abstract][Full Text] [Related]  

  • 35. A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.
    Zhang J; Kim J; Alexander A; Cai S; Tripathi DN; Dere R; Tee AR; Tait-Mulder J; Di Nardo A; Han JM; Kwiatkowski E; Dunlop EA; Dodd KM; Folkerth RD; Faust PL; Kastan MB; Sahin M; Walker CL
    Nat Cell Biol; 2013 Oct; 15(10):1186-96. PubMed ID: 23955302
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Chronic activation of mTOR complex 1 is sufficient to cause hepatocellular carcinoma in mice.
    Menon S; Yecies JL; Zhang HH; Howell JJ; Nicholatos J; Harputlugil E; Bronson RT; Kwiatkowski DJ; Manning BD
    Sci Signal; 2012 Mar; 5(217):ra24. PubMed ID: 22457330
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Mammalian target of rapamycin and tuberous sclerosis complex.
    Wataya-Kaneda M
    J Dermatol Sci; 2015 Aug; 79(2):93-100. PubMed ID: 26051878
    [TBL] [Abstract][Full Text] [Related]  

  • 38. HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice.
    Samardzija M; Corna A; Gomez-Sintes R; Jarboui MA; Armento A; Roger JE; Petridou E; Haq W; Paquet-Durand F; Zrenner E; de la Villa P; Zeck G; Grimm C; Boya P; Ueffing M; Trifunović D
    Cell Death Differ; 2021 Apr; 28(4):1317-1332. PubMed ID: 33159184
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion.
    Zhou J; Tan SH; Nicolas V; Bauvy C; Yang ND; Zhang J; Xue Y; Codogno P; Shen HM
    Cell Res; 2013 Apr; 23(4):508-23. PubMed ID: 23337583
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The amino acid transporter SLC38A9 regulates MTORC1 and autophagy.
    Jin M; Klionsky DJ
    Autophagy; 2015; 11(10):1709-10. PubMed ID: 26506891
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 19.