171 related articles for article (PubMed ID: 27363940)
1. Kinetic investigation of human 5-lipoxygenase with arachidonic acid.
Mittal M; Kumar RB; Balagunaseelan N; Hamberg M; Jegerschöld C; Rådmark O; Haeggström JZ; Rinaldo-Matthis A
Bioorg Med Chem Lett; 2016 Aug; 26(15):3547-51. PubMed ID: 27363940
[TBL] [Abstract][Full Text] [Related]
2. 5-Lipoxygenase as a drug target: A review on trends in inhibitors structural design, SAR and mechanism based approach.
Sinha S; Doble M; Manju SL
Bioorg Med Chem; 2019 Sep; 27(17):3745-3759. PubMed ID: 31331653
[TBL] [Abstract][Full Text] [Related]
3. 5 S,15 S-Dihydroperoxyeicosatetraenoic Acid (5,15-diHpETE) as a Lipoxin Intermediate: Reactivity and Kinetics with Human Leukocyte 5-Lipoxygenase, Platelet 12-Lipoxygenase, and Reticulocyte 15-Lipoxygenase-1.
Green AR; Freedman C; Tena J; Tourdot BE; Liu B; Holinstat M; Holman TR
Biochemistry; 2018 Dec; 57(48):6726-6734. PubMed ID: 30407793
[TBL] [Abstract][Full Text] [Related]
4. Kinetic investigation of the rate-limiting step of manganese- and iron-lipoxygenases.
Wennman A; Karkehabadi S; Oliw EH
Arch Biochem Biophys; 2014 Aug; 555-556():9-15. PubMed ID: 24857825
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of the enzymes in the leukotriene and prostaglandin pathways in inflammation by 3-aryl isocoumarins.
Ramanan M; Sinha S; Sudarshan K; Aidhen IS; Doble M
Eur J Med Chem; 2016 Nov; 124():428-434. PubMed ID: 27597418
[TBL] [Abstract][Full Text] [Related]
6. Understanding the Mechanism of the Hydrogen Abstraction from Arachidonic Acid Catalyzed by the Human Enzyme 15-Lipoxygenase-2. A Quantum Mechanics/Molecular Mechanics Free Energy Simulation.
Suardíaz R; Jambrina PG; Masgrau L; González-Lafont À; Rosta E; Lluch JM
J Chem Theory Comput; 2016 Apr; 12(4):2079-90. PubMed ID: 26918937
[TBL] [Abstract][Full Text] [Related]
7. 5-Lipoxygenase-activating protein rescues activity of 5-lipoxygenase mutations that delay nuclear membrane association and disrupt product formation.
Gerstmeier J; Newcomer ME; Dennhardt S; Romp E; Fischer J; Werz O; Garscha U
FASEB J; 2016 May; 30(5):1892-900. PubMed ID: 26842853
[TBL] [Abstract][Full Text] [Related]
8. Lipidomics Reveals Dramatic Physiological Kinetic Isotope Effects during the Enzymatic Oxygenation of Polyunsaturated Fatty Acids Ex Vivo.
Navratil AR; Shchepinov MS; Dennis EA
J Am Chem Soc; 2018 Jan; 140(1):235-243. PubMed ID: 29206462
[TBL] [Abstract][Full Text] [Related]
9. Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells.
Ding XZ; Iversen P; Cluck MW; Knezetic JA; Adrian TE
Biochem Biophys Res Commun; 1999 Jul; 261(1):218-23. PubMed ID: 10405349
[TBL] [Abstract][Full Text] [Related]
10. Identification of 6-benzyloxysalicylates as a novel class of inhibitors of 15-lipoxygenase-1.
Eleftheriadis N; Thee S; te Biesebeek J; van der Wouden P; Baas BJ; Dekker FJ
Eur J Med Chem; 2015 Apr; 94():265-75. PubMed ID: 25771032
[TBL] [Abstract][Full Text] [Related]
11. 5-LOX inhibitor modulates the inflammatory responses provoked by Helicobacter pylori infection.
Park S; Han SU; Lee KM; Park KH; Cho SW; Hahm KB
Helicobacter; 2007 Feb; 12(1):49-58. PubMed ID: 17241301
[TBL] [Abstract][Full Text] [Related]
12. Identification of NSAIDs as lipoxygenase inhibitors through highly sensitive chemiluminescence method, expression analysis in mononuclear cells and computational studies.
Shahid W; Ejaz SA; Al-Rashida M; Saleem M; Ahmed M; Rahman J; Riaz N; Ashraf M
Bioorg Chem; 2021 May; 110():104818. PubMed ID: 33784531
[TBL] [Abstract][Full Text] [Related]
13. Kinetic investigations of the rate-limiting step in human 12- and 15-lipoxygenase.
Segraves EN; Holman TR
Biochemistry; 2003 May; 42(18):5236-43. PubMed ID: 12731864
[TBL] [Abstract][Full Text] [Related]
14. Anacardic acid derived salicylates are inhibitors or activators of lipoxygenases.
Wisastra R; Ghizzoni M; Boltjes A; Haisma HJ; Dekker FJ
Bioorg Med Chem; 2012 Aug; 20(16):5027-32. PubMed ID: 22789707
[TBL] [Abstract][Full Text] [Related]
15. ATP allosterically activates the human 5-lipoxygenase molecular mechanism of arachidonic acid and 5(S)-hydroperoxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid.
Smyrniotis CJ; Barbour SR; Xia Z; Hixon MS; Holman TR
Biochemistry; 2014 Jul; 53(27):4407-19. PubMed ID: 24893149
[TBL] [Abstract][Full Text] [Related]
16. Strict Regiospecificity of Human Epithelial 15-Lipoxygenase-2 Delineates Its Transcellular Synthesis Potential.
Green AR; Barbour S; Horn T; Carlos J; Raskatov JA; Holman TR
Biochemistry; 2016 May; 55(20):2832-40. PubMed ID: 27145229
[TBL] [Abstract][Full Text] [Related]
17. The different inhibitory effects of Huang-Lian-Jie-Du-Tang on cyclooxygenase 2 and 5-lipoxygenase.
Li L; Zeng H; Shan L; Yuan X; Li Y; Liu R; Zhang W
J Ethnopharmacol; 2012 Sep; 143(2):732-9. PubMed ID: 22884869
[TBL] [Abstract][Full Text] [Related]
18. Fatty acid release and oxidation are factors in lipoxygenase inhibitor-induced apoptosis.
La E; Kern JC; Atarod EB; Kehrer JP
Toxicol Lett; 2003 Mar; 138(3):193-203. PubMed ID: 12565196
[TBL] [Abstract][Full Text] [Related]
19. Interfacial catalysis and production of a high ratio of leukotriene A4 to 5-HPETE by 5-lipoxygenase in a coupled assay with phospholipase A2.
Riendeau D; Falgueyret JP; Meisner D; Sherman MM; Laliberté F; Street IP
J Lipid Mediat; 1993; 6(1-3):23-30. PubMed ID: 8395245
[TBL] [Abstract][Full Text] [Related]
20. 5-Lipoxygenase inhibitors attenuate growth of human renal cell carcinoma and induce apoptosis through arachidonic acid pathway.
Matsuyama M; Yoshimura R; Mitsuhashi M; Tsuchida K; Takemoto Y; Kawahito Y; Sano H; Nakatani T
Oncol Rep; 2005 Jul; 14(1):73-9. PubMed ID: 15944770
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]