210 related articles for article (PubMed ID: 27364102)
41. p62/sequestosome 1 as a regulator of proteasome inhibitor-induced autophagy in human retinal pigment epithelial cells.
Viiri J; Hyttinen JM; Ryhänen T; Rilla K; Paimela T; Kuusisto E; Siitonen A; Urtti A; Salminen A; Kaarniranta K
Mol Vis; 2010 Jul; 16():1399-414. PubMed ID: 20680098
[TBL] [Abstract][Full Text] [Related]
42. LRRK2 interacts with the vacuolar-type H+-ATPase pump a1 subunit to regulate lysosomal function.
Wallings R; Connor-Robson N; Wade-Martins R
Hum Mol Genet; 2019 Aug; 28(16):2696-2710. PubMed ID: 31039583
[TBL] [Abstract][Full Text] [Related]
43. A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells.
Milan E; Perini T; Resnati M; Orfanelli U; Oliva L; Raimondi A; Cascio P; Bachi A; Marcatti M; Ciceri F; Cenci S
Autophagy; 2015; 11(7):1161-78. PubMed ID: 26043024
[TBL] [Abstract][Full Text] [Related]
44. Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability.
Ding WX; Ni HM; Gao W; Yoshimori T; Stolz DB; Ron D; Yin XM
Am J Pathol; 2007 Aug; 171(2):513-24. PubMed ID: 17620365
[TBL] [Abstract][Full Text] [Related]
45. The LRRK2 inhibitor GSK2578215A induces protective autophagy in SH-SY5Y cells: involvement of Drp-1-mediated mitochondrial fission and mitochondrial-derived ROS signaling.
Saez-Atienzar S; Bonet-Ponce L; Blesa JR; Romero FJ; Murphy MP; Jordan J; Galindo MF
Cell Death Dis; 2014 Aug; 5(8):e1368. PubMed ID: 25118928
[TBL] [Abstract][Full Text] [Related]
46. Kinase activity of mutant LRRK2 manifests differently in hetero-dimeric vs. homo-dimeric complexes.
Leandrou E; Markidi E; Memou A; Melachroinou K; Greggio E; Rideout HJ
Biochem J; 2019 Feb; 476(3):559-579. PubMed ID: 30670570
[TBL] [Abstract][Full Text] [Related]
47. Inhibition of HDAC6 modifies tau inclusion body formation and impairs autophagic clearance.
Leyk J; Goldbaum O; Noack M; Richter-Landsberg C
J Mol Neurosci; 2015 Apr; 55(4):1031-46. PubMed ID: 25434725
[TBL] [Abstract][Full Text] [Related]
48. Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability--a point of convergence in parkinsonian neurodegeneration?
Gillardon F
J Neurochem; 2009 Sep; 110(5):1514-22. PubMed ID: 19545277
[TBL] [Abstract][Full Text] [Related]
49. Adenoviral-mediated expression of G2019S LRRK2 induces striatal pathology in a kinase-dependent manner in a rat model of Parkinson's disease.
Tsika E; Nguyen AP; Dusonchet J; Colin P; Schneider BL; Moore DJ
Neurobiol Dis; 2015 May; 77():49-61. PubMed ID: 25731749
[TBL] [Abstract][Full Text] [Related]
50. LRRK2 G2019S-induced mitochondrial DNA damage is LRRK2 kinase dependent and inhibition restores mtDNA integrity in Parkinson's disease.
Howlett EH; Jensen N; Belmonte F; Zafar F; Hu X; Kluss J; Schüle B; Kaufman BA; Greenamyre JT; Sanders LH
Hum Mol Genet; 2017 Nov; 26(22):4340-4351. PubMed ID: 28973664
[TBL] [Abstract][Full Text] [Related]
51. Adaptive changes in autophagy after UPS impairment in Parkinson's disease.
Shen YF; Tang Y; Zhang XJ; Huang KX; Le WD
Acta Pharmacol Sin; 2013 May; 34(5):667-73. PubMed ID: 23503475
[TBL] [Abstract][Full Text] [Related]
52. Interplay of LRRK2 with chaperone-mediated autophagy.
Orenstein SJ; Kuo SH; Tasset I; Arias E; Koga H; Fernandez-Carasa I; Cortes E; Honig LS; Dauer W; Consiglio A; Raya A; Sulzer D; Cuervo AM
Nat Neurosci; 2013 Apr; 16(4):394-406. PubMed ID: 23455607
[TBL] [Abstract][Full Text] [Related]
53. UCH-L1 Inhibition Suppresses tau Aggresome Formation during Proteasomal Impairment.
Yu Q; Zhang H; Li Y; Liu C; Wang S; Liao X
Mol Neurobiol; 2018 May; 55(5):3812-3821. PubMed ID: 28540657
[TBL] [Abstract][Full Text] [Related]
54. Prevention of intracellular degradation of I2020T mutant LRRK2 restores its protectivity against apoptosis.
Ohta E; Kubo M; Obata F
Biochem Biophys Res Commun; 2010 Jan; 391(1):242-7. PubMed ID: 19912990
[TBL] [Abstract][Full Text] [Related]
55. LRRK2 activity does not dramatically alter α-synuclein pathology in primary neurons.
Henderson MX; Peng C; Trojanowski JQ; Lee VMY
Acta Neuropathol Commun; 2018 May; 6(1):45. PubMed ID: 29855356
[TBL] [Abstract][Full Text] [Related]
56. Inhibition of SQSTM1 S403 phosphorylation facilitates the aggresome formation of ubiquitinated proteins during proteasome dysfunction.
Zhang C; Duan Y; Huang C; Li L
Cell Mol Biol Lett; 2023 Oct; 28(1):85. PubMed ID: 37872526
[TBL] [Abstract][Full Text] [Related]
57. Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble α-synuclein in neurons.
Schapansky J; Khasnavis S; DeAndrade MP; Nardozzi JD; Falkson SR; Boyd JD; Sanderson JB; Bartels T; Melrose HL; LaVoie MJ
Neurobiol Dis; 2018 Mar; 111():26-35. PubMed ID: 29246723
[TBL] [Abstract][Full Text] [Related]
58. LRRK2 G2019S Mutation Inhibits Degradation of α-Synuclein in an In Vitro Model of Parkinson's Disease.
Hu D; Niu JY; Xiong J; Nie SK; Zeng F; Zhang ZH
Curr Med Sci; 2018 Dec; 38(6):1012-1017. PubMed ID: 30536063
[TBL] [Abstract][Full Text] [Related]
59. Parkin Protects Against Misfolded SOD1 Toxicity by Promoting Its Aggresome Formation and Autophagic Clearance.
Yung C; Sha D; Li L; Chin LS
Mol Neurobiol; 2016 Nov; 53(9):6270-6287. PubMed ID: 26563499
[TBL] [Abstract][Full Text] [Related]
60. Evidence that the LRRK2 ROC domain Parkinson's disease-associated mutants A1442P and R1441C exhibit increased intracellular degradation.
Greene ID; Mastaglia F; Meloni BP; West KA; Chieng J; Mitchell CJ; Gai WP; Boulos S
J Neurosci Res; 2014 Apr; 92(4):506-16. PubMed ID: 24375786
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
