197 related articles for article (PubMed ID: 27364561)
21. Histone markers identify the mode of action for compounds positive in the TK6 micronucleus assay.
Cheung JR; Dickinson DA; Moss J; Schuler MJ; Spellman RA; Heard PL
Mutat Res Genet Toxicol Environ Mutagen; 2015 Jan; 777():7-16. PubMed ID: 25726170
[TBL] [Abstract][Full Text] [Related]
22. The predominant role of apoptosis in γH2AX formation induced by aneugens is useful for distinguishing aneugens from clastogens.
Harada A; Matsuzaki K; Takeiri A; Mishima M
Mutat Res Genet Toxicol Environ Mutagen; 2014 Sep; 771():23-9. PubMed ID: 25308438
[TBL] [Abstract][Full Text] [Related]
23. Evidence for an Aneugenic Mechanism of Action for Micronucleus Induction by Black Cohosh Extract.
Bernacki DT; Bryce SM; Bemis JC; Dertinger SD; Witt KL; Smith-Roe SL
Environ Mol Mutagen; 2019 Dec; 60(9):845-856. PubMed ID: 31569270
[TBL] [Abstract][Full Text] [Related]
24. Comparative analysis of micronucleus induction and DNA damage biomarkers in TK6 and A375 cells using flow cytometry.
Sun X; Spellman RA; Engel M; Rubitski E; Schuler M
Environ Mol Mutagen; 2024; 65(1-2):25-46. PubMed ID: 38333939
[TBL] [Abstract][Full Text] [Related]
25. Involvement of p53 function in different magnitude of genotoxic and cytotoxic responses in in vitro micronucleus assays.
Hashimoto K; Nakajima Y; Uematsu R; Matsumura S; Chatani F
Mutat Res; 2011 Nov; 726(1):21-8. PubMed ID: 21855649
[TBL] [Abstract][Full Text] [Related]
26. Difference in susceptibility to morphological changes in the nucleus to aneugens between p53-competent and p53-abrogated lymphoblastoid cell lines (TK6 and NH32 cells) in the in vitro micronucleus assay.
Hashimoto K; Nakajima Y; Uematsu R; Chatani F
Mutagenesis; 2012 May; 27(3):287-93. PubMed ID: 22042714
[TBL] [Abstract][Full Text] [Related]
27. A new imaging platform (iScreen) allows for the concurrent assessment of micronucleus induction and genotoxic mode of action in human A375 cells.
Sun X; Rubitski E; Spellman RA; Engel M; Schuler M
Environ Mol Mutagen; 2022 Jun; 63(5):230-245. PubMed ID: 35703118
[TBL] [Abstract][Full Text] [Related]
28. The TGx-28.65 biomarker online application for analysis of transcriptomics data to identify DNA damage-inducing chemicals in human cell cultures.
Jackson MA; Yang L; Lea I; Rashid A; Kuo B; Williams A; Lyn Yauk C; Fostel J
Environ Mol Mutagen; 2017 Aug; 58(7):529-535. PubMed ID: 28766826
[TBL] [Abstract][Full Text] [Related]
29. Benchmark Dose Analysis of DNA Damage Biomarker Responses Provides Compound Potency and Adverse Outcome Pathway Information for the Topoisomerase II Inhibitor Class of Compounds.
Wheeldon RP; Bernacki DT; Dertinger SD; Bryce SM; Bemis JC; Johnson GE
Environ Mol Mutagen; 2020 Apr; 61(4):396-407. PubMed ID: 31983063
[TBL] [Abstract][Full Text] [Related]
30. An evaluation of 25 selected ToxCast chemicals in medium-throughput assays to detect genotoxicity.
Kligerman AD; Young RR; Stankowski LF; Pant K; Lawlor T; Aardema MJ; Houck KA
Environ Mol Mutagen; 2015 Jun; 56(5):468-76. PubMed ID: 25537651
[TBL] [Abstract][Full Text] [Related]
31. Genotoxicity evaluation of carbon monoxide and 1,3-butadiene using a new joint technology: the in vitro γH2AX HCS assay combined with air-liquid interface system.
Zhang S; Chen H; Wang A; Liu Y; Hou H; Hu Q
Toxicol Mech Methods; 2019 Jan; 29(1):1-7. PubMed ID: 29779429
[TBL] [Abstract][Full Text] [Related]
32. The characterization of γH2AX and p53 as biomarkers of genotoxic stress in a rainbow trout (Oncorhynchus mykiss) brain cell line.
Hamilton ME; Bols NC; Duncker BP
Chemosphere; 2018 Jun; 201():850-858. PubMed ID: 29554631
[TBL] [Abstract][Full Text] [Related]
33. Biomarkers of DNA damage response improve in vitro micronucleus assays by revealing genotoxic mode of action and reducing the occurrence of irrelevant positive results.
Avlasevich S; Pellegrin T; Godse M; Bryce S; Bemis J; Bajorski P; Dertinger S
Mutagenesis; 2021 Nov; 36(6):407-418. PubMed ID: 34718711
[TBL] [Abstract][Full Text] [Related]
34. In vitro and in silico genetic toxicity screening of flavor compounds and other ingredients in tobacco products with emphasis on ENDS.
Hung PH; Savidge M; De M; Kang JC; Healy SM; Valerio LG
J Appl Toxicol; 2020 Nov; 40(11):1566-1587. PubMed ID: 32662109
[TBL] [Abstract][Full Text] [Related]
35. Performance of in vitro γH2AX assay in HepG2 cells to predict in vivo genotoxicity.
Tsamou M; Jennen DG; Claessen SM; Magkoufopoulou C; Kleinjans JC; van Delft JH
Mutagenesis; 2012 Nov; 27(6):645-52. PubMed ID: 22914676
[TBL] [Abstract][Full Text] [Related]
36. An in vitro micronucleus assay with size-classified micronucleus counting to discriminate aneugens from clastogens.
Hashimoto K; Nakajima Y; Matsumura S; Chatani F
Toxicol In Vitro; 2010 Feb; 24(1):208-16. PubMed ID: 19747535
[TBL] [Abstract][Full Text] [Related]
37. The utility of metabolic activation mixtures containing human hepatic post-mitochondrial supernatant (S9) for in vitro genetic toxicity assessment.
Cox JA; Fellows MD; Hashizume T; White PA
Mutagenesis; 2016 Mar; 31(2):117-30. PubMed ID: 26712374
[TBL] [Abstract][Full Text] [Related]
38. How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.
Kirkland D; Pfuhler S; Tweats D; Aardema M; Corvi R; Darroudi F; Elhajouji A; Glatt H; Hastwell P; Hayashi M; Kasper P; Kirchner S; Lynch A; Marzin D; Maurici D; Meunier JR; Müller L; Nohynek G; Parry J; Parry E; Thybaud V; Tice R; van Benthem J; Vanparys P; White P
Mutat Res; 2007 Mar; 628(1):31-55. PubMed ID: 17293159
[TBL] [Abstract][Full Text] [Related]
39. Whole cell-ELISA to measure the gammaH2AX response of six aneugens and eight DNA-damaging chemicals.
Matsuzaki K; Harada A; Takeiri A; Tanaka K; Mishima M
Mutat Res; 2010 Jul; 700(1-2):71-9. PubMed ID: 20580854
[TBL] [Abstract][Full Text] [Related]
40. The γH2AX assay for genotoxic and nongenotoxic agents: comparison of H2AX phosphorylation with cell death response.
Nikolova T; Dvorak M; Jung F; Adam I; Krämer E; Gerhold-Ay A; Kaina B
Toxicol Sci; 2014 Jul; 140(1):103-17. PubMed ID: 24743697
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
