BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 27373892)

  • 1. Therapeutic Targeting of the IL-6 Trans-Signaling/Mechanistic Target of Rapamycin Complex 1 Axis in Pulmonary Emphysema.
    Ruwanpura SM; McLeod L; Dousha LF; Seow HJ; Alhayyani S; Tate MD; Deswaerte V; Brooks GD; Bozinovski S; MacDonald M; Garbers C; King PT; Bardin PG; Vlahos R; Rose-John S; Anderson GP; Jenkins BJ
    Am J Respir Crit Care Med; 2016 Dec; 194(12):1494-1505. PubMed ID: 27373892
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interleukin-6 promotes pulmonary emphysema associated with apoptosis in mice.
    Ruwanpura SM; McLeod L; Miller A; Jones J; Bozinovski S; Vlahos R; Ernst M; Armes J; Bardin PG; Anderson GP; Jenkins BJ
    Am J Respir Cell Mol Biol; 2011 Oct; 45(4):720-30. PubMed ID: 21297079
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IL-6/Stat3-driven pulmonary inflammation, but not emphysema, is dependent on interleukin-17A in mice.
    Ruwanpura SM; McLeod L; Brooks GD; Bozinovski S; Vlahos R; Longano A; Bardin PG; Anderson GP; Jenkins BJ
    Respirology; 2014 Apr; 19(3):419-27. PubMed ID: 24506702
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cross-talk between IL-6 trans-signaling and AIM2 inflammasome/IL-1β axes bridge innate immunity and epithelial apoptosis to promote emphysema.
    Ruwanpura SM; McLeod L; Dousha LF; Seow HJ; West AC; West AJ; Weng T; Alanazi M; MacDonald M; King PT; Bardin PG; Gabay C; Klinman DM; Bozinovski S; Vlahos R; Anderson GP; Rose-John S; Saad MI; Jenkins BJ
    Proc Natl Acad Sci U S A; 2022 Sep; 119(36):e2201494119. PubMed ID: 36037355
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rapamycin attenuates Tc1 and Tc17 cell responses in cigarette smoke-induced emphysema in mice.
    Zhang H; Zhou X; Chen X; Lin Y; Qiu S; Zhao Y; Tang Q; Liang Y; Zhong X
    Inflamm Res; 2019 Nov; 68(11):957-968. PubMed ID: 31468083
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice.
    Ruwanpura SM; McLeod L; Miller A; Jones J; Vlahos R; Ramm G; Longano A; Bardin PG; Bozinovski S; Anderson GP; Jenkins BJ
    Am J Physiol Lung Cell Mol Physiol; 2012 Apr; 302(7):L627-39. PubMed ID: 22268122
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Blockade of the IL-6 trans-signalling/STAT3 axis suppresses cachexia in Kras-induced lung adenocarcinoma.
    Miller A; McLeod L; Alhayyani S; Szczepny A; Watkins DN; Chen W; Enriori P; Ferlin W; Ruwanpura S; Jenkins BJ
    Oncogene; 2017 May; 36(21):3059-3066. PubMed ID: 27893707
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Impact of interleukin-6 classic- and trans-signaling on liver damage and regeneration.
    Drucker C; Gewiese J; Malchow S; Scheller J; Rose-John S
    J Autoimmun; 2010 Feb; 34(1):29-37. PubMed ID: 19717281
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Selective blockade of interleukin-6 trans-signaling improves survival in a murine polymicrobial sepsis model.
    Barkhausen T; Tschernig T; Rosenstiel P; van Griensven M; Vonberg RP; Dorsch M; Mueller-Heine A; Chalaris A; Scheller J; Rose-John S; Seegert D; Krettek C; Waetzig GH
    Crit Care Med; 2011 Jun; 39(6):1407-13. PubMed ID: 21336117
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of blockade of peripheral interleukin-6 trans-signaling on hippocampus-dependent and independent memory in mice.
    Braun O; Dewitz C; Möller-Hackbarth K; Scheller J; Schiffelholz T; Baier PC; Rose-John S
    J Interferon Cytokine Res; 2013 May; 33(5):254-60. PubMed ID: 23215755
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Local blockade of IL-6R signaling induces lung CD4+ T cell apoptosis in a murine model of asthma via regulatory T cells.
    Finotto S; Eigenbrod T; Karwot R; Boross I; Doganci A; Ito H; Nishimoto N; Yoshizaki K; Kishimoto T; Rose-John S; Galle PR; Neurath MF
    Int Immunol; 2007 Jun; 19(6):685-93. PubMed ID: 17496315
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hitting a complex target: an update on interleukin-6 trans-signalling.
    Waetzig GH; Rose-John S
    Expert Opin Ther Targets; 2012 Feb; 16(2):225-36. PubMed ID: 22324903
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Thalidomide prevents cigarette smoke extract-induced lung damage in mice.
    Tabata C; Tabata R; Takahashi Y; Nakamura K; Nakano T
    Int Immunopharmacol; 2015 Apr; 25(2):511-7. PubMed ID: 25749497
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interleukin-11-driven gastric tumourigenesis is independent of trans-signalling.
    Balic JJ; Garbers C; Rose-John S; Yu L; Jenkins BJ
    Cytokine; 2017 Apr; 92():118-123. PubMed ID: 28160627
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interleukin-6 and its receptors: a highly regulated and dynamic system.
    Wolf J; Rose-John S; Garbers C
    Cytokine; 2014 Nov; 70(1):11-20. PubMed ID: 24986424
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema.
    Yoshida T; Mett I; Bhunia AK; Bowman J; Perez M; Zhang L; Gandjeva A; Zhen L; Chukwueke U; Mao T; Richter A; Brown E; Ashush H; Notkin N; Gelfand A; Thimmulappa RK; Rangasamy T; Sussan T; Cosgrove G; Mouded M; Shapiro SD; Petrache I; Biswal S; Feinstein E; Tuder RM
    Nat Med; 2010 Jul; 16(7):767-73. PubMed ID: 20473305
    [TBL] [Abstract][Full Text] [Related]  

  • 17. IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3.
    Greenhill CJ; Rose-John S; Lissilaa R; Ferlin W; Ernst M; Hertzog PJ; Mansell A; Jenkins BJ
    J Immunol; 2011 Jan; 186(2):1199-208. PubMed ID: 21148800
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo.
    Atreya R; Mudter J; Finotto S; Müllberg J; Jostock T; Wirtz S; Schütz M; Bartsch B; Holtmann M; Becker C; Strand D; Czaja J; Schlaak JF; Lehr HA; Autschbach F; Schürmann G; Nishimoto N; Yoshizaki K; Ito H; Kishimoto T; Galle PR; Rose-John S; Neurath MF
    Nat Med; 2000 May; 6(5):583-8. PubMed ID: 10802717
    [TBL] [Abstract][Full Text] [Related]  

  • 19. IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema.
    Couillin I; Vasseur V; Charron S; Gasse P; Tavernier M; Guillet J; Lagente V; Fick L; Jacobs M; Coelho FR; Moser R; Ryffel B
    J Immunol; 2009 Dec; 183(12):8195-202. PubMed ID: 20007584
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model.
    Matsumoto S; Hara T; Mitsuyama K; Yamamoto M; Tsuruta O; Sata M; Scheller J; Rose-John S; Kado S; Takada T
    J Immunol; 2010 Feb; 184(3):1543-51. PubMed ID: 20042582
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.