These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
217 related articles for article (PubMed ID: 27374490)
1. Discovery and structural optimization of 4-(4-(benzyloxy)phenyl)-3,4-dihydropyrimidin-2(1H)-ones as RORc inverse agonists. Wu XS; Wang R; Xing YL; Xue XQ; Zhang Y; Lu YZ; Song Y; Luo XY; Wu C; Zhou YL; Jiang JQ; Xu Y Acta Pharmacol Sin; 2016 Nov; 37(11):1516-1524. PubMed ID: 27374490 [TBL] [Abstract][Full Text] [Related]
2. Discovery of 1-{4-[3-fluoro-4-((3s,6r)-3-methyl-1,1-dioxo-6-phenyl-[1,2]thiazinan-2-ylmethyl)-phenyl]-piperazin-1-yl}-ethanone (GNE-3500): a potent, selective, and orally bioavailable retinoic acid receptor-related orphan receptor C (RORc or RORγ) inverse agonist. Fauber BP; René O; Deng Y; DeVoss J; Eidenschenk C; Everett C; Ganguli A; Gobbi A; Hawkins J; Johnson AR; La H; Lesch J; Lockey P; Norman M; Ouyang W; Summerhill S; Wong H J Med Chem; 2015 Jul; 58(13):5308-22. PubMed ID: 26061388 [TBL] [Abstract][Full Text] [Related]
3. Identification of N-phenyl-2-(N-phenylphenylsulfonamido)acetamides as new RORγ inverse agonists: Virtual screening, structure-based optimization, and biological evaluation. Song Y; Xue X; Wu X; Wang R; Xing Y; Yan W; Zhou Y; Qian CN; Zhang Y; Xu Y Eur J Med Chem; 2016 Jun; 116():13-26. PubMed ID: 27043267 [TBL] [Abstract][Full Text] [Related]
4. Identification of N-sulfonyl-tetrahydroquinolines as RORc inverse agonists. Fauber BP; Gobbi A; Savy P; Burton B; Deng Y; Everett C; La H; Johnson AR; Lockey P; Norman M; Wong H Bioorg Med Chem Lett; 2015 Oct; 25(19):4109-13. PubMed ID: 26321361 [TBL] [Abstract][Full Text] [Related]
5. Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists. Fauber BP; Gobbi A; Robarge K; Zhou A; Barnard A; Cao J; Deng Y; Eidenschenk C; Everett C; Ganguli A; Hawkins J; Johnson AR; La H; Norman M; Salmon G; Summerhill S; Ouyang W; Tang W; Wong H Bioorg Med Chem Lett; 2015 Aug; 25(15):2907-12. PubMed ID: 26048793 [TBL] [Abstract][Full Text] [Related]
6. Identification of tertiary sulfonamides as RORc inverse agonists. Fauber BP; René O; Burton B; Everett C; Gobbi A; Hawkins J; Johnson AR; Liimatta M; Lockey P; Norman M; Wong H Bioorg Med Chem Lett; 2014 May; 24(9):2182-7. PubMed ID: 24685544 [TBL] [Abstract][Full Text] [Related]
7. Discovery of [ cis-3-({(5 R)-5-[(7-Fluoro-1,1-dimethyl-2,3-dihydro-1 H-inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5 H)-yl}carbonyl)cyclobutyl]acetic Acid (TAK-828F) as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor γt Inverse Agonist. Kono M; Ochida A; Oda T; Imada T; Banno Y; Taya N; Masada S; Kawamoto T; Yonemori K; Nara Y; Fukase Y; Yukawa T; Tokuhara H; Skene R; Sang BC; Hoffman ID; Snell GP; Uga K; Shibata A; Igaki K; Nakamura Y; Nakagawa H; Tsuchimori N; Yamasaki M; Shirai J; Yamamoto S J Med Chem; 2018 Apr; 61(7):2973-2988. PubMed ID: 29510038 [TBL] [Abstract][Full Text] [Related]
8. Structure-Based Design and Synthesis of Fluorene Derivatives as Novel RORγt Inverse Agonists. Gabr MT; Abdel-Raziq MS Chem Biodivers; 2018 Sep; 15(9):e1800244. PubMed ID: 29935095 [TBL] [Abstract][Full Text] [Related]
9. A reversed sulfonamide series of selective RORc inverse agonists. van Niel MB; Fauber BP; Cartwright M; Gaines S; Killen JC; René O; Ward SI; de Leon Boenig G; Deng Y; Eidenschenk C; Everett C; Gancia E; Ganguli A; Gobbi A; Hawkins J; Johnson AR; Kiefer JR; La H; Lockey P; Norman M; Ouyang W; Qin A; Wakes N; Waszkowycz B; Wong H Bioorg Med Chem Lett; 2014 Dec; 24(24):5769-5776. PubMed ID: 25453817 [TBL] [Abstract][Full Text] [Related]
10. Discovery of 1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxide analogs as new RORC modulators. Muegge I; Collin D; Cook B; Hill-Drzewi M; Horan J; Kugler S; Labadia M; Li X; Smith L; Zhang Y Bioorg Med Chem Lett; 2015 May; 25(9):1892-5. PubMed ID: 25840886 [TBL] [Abstract][Full Text] [Related]
11. Discovery of novel triazine derivatives as potent retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists. Lu L; Chen S; Yu M; Zhou R; Guo S; Chen JA; Wang H; Chen S; Luo C; Xie Q; Wang Y Eur J Med Chem; 2023 Aug; 256():115424. PubMed ID: 37167779 [TBL] [Abstract][Full Text] [Related]
12. Design and synthesis of novel ROR inverse agonists with a dibenzosilole scaffold as a hydrophobic core structure. Toyama H; Nakamura M; Hashimoto Y; Fujii S Bioorg Med Chem; 2015 Jul; 23(13):2982-8. PubMed ID: 26014484 [TBL] [Abstract][Full Text] [Related]
13. Identification of Corosolic and Oleanolic Acids as Molecules Antagonizing the Human RORγT Nuclear Receptor Using the Calculated Fingerprints of the Molecular Similarity. Pastwińska J; Karaś K; Sałkowska A; Karwaciak I; Chałaśkiewicz K; Wojtczak BA; Bachorz RA; Ratajewski M Int J Mol Sci; 2022 Feb; 23(3):. PubMed ID: 35163824 [TBL] [Abstract][Full Text] [Related]
14. Identification of novel quinazolinedione derivatives as RORγt inverse agonist. Fukase Y; Sato A; Tomata Y; Ochida A; Kono M; Yonemori K; Koga K; Okui T; Yamasaki M; Fujitani Y; Nakagawa H; Koyama R; Nakayama M; Skene R; Sang BC; Hoffman I; Shirai J; Yamamoto S Bioorg Med Chem; 2018 Feb; 26(3):721-736. PubMed ID: 29342416 [TBL] [Abstract][Full Text] [Related]
15. Discovery of N-indanyl benzamides as potent RORγt inverse agonists. Tian J; Sun N; Yu M; Gu X; Xie Q; Shao L; Liu J; Liu L; Wang Y Eur J Med Chem; 2019 Apr; 167():37-48. PubMed ID: 30743096 [TBL] [Abstract][Full Text] [Related]
16. Discovery and pharmacological evaluation of indole derivatives as potent and selective RORγt inverse agonist for multiple autoimmune conditions. Shaikh NS; Iyer JP; Munot YS; Mukhopadhyay PP; Raje AA; Nagaraj R; Jamdar V; Gavhane R; Lohote M; Sherkar P; Bala M; Petla R; Meru A; Umrani D; Rouduri S; Joshi S; Reddy S; Kandikere V; Bhuniya D; Kulkarni B; Mookhtiar KA Bioorg Med Chem Lett; 2019 Aug; 29(16):2208-2217. PubMed ID: 31272795 [TBL] [Abstract][Full Text] [Related]
17. Discovery of carbazole carboxamides as novel RORγt inverse agonists. Huang Y; Yu M; Sun N; Tang T; Yu F; Song X; Xie Q; Fu W; Shao L; Wang Y Eur J Med Chem; 2018 Mar; 148():465-476. PubMed ID: 29477887 [TBL] [Abstract][Full Text] [Related]
18. Modulators of the nuclear receptor retinoic acid receptor-related orphan receptor-γ (RORγ or RORc). Fauber BP; Magnuson S J Med Chem; 2014 Jul; 57(14):5871-92. PubMed ID: 24502334 [TBL] [Abstract][Full Text] [Related]
19. Discovery of novel N-sulfonamide-tetrahydroquinolines as potent retinoic acid receptor-related orphan receptor γt inverse agonists for the treatment of autoimmune diseases. Sun N; Ma X; Zhou K; Zhu C; Cao Z; Wang Y; Xu J; Fu W Eur J Med Chem; 2020 Feb; 187():111984. PubMed ID: 31881455 [TBL] [Abstract][Full Text] [Related]
20. Discovery of N-(4-aryl-5-aryloxy-thiazol-2-yl)-amides as potent RORγt inverse agonists. Wang Y; Yang T; Liu Q; Ma Y; Yang L; Zhou L; Xiang Z; Cheng Z; Lu S; Orband-Miller LA; Zhang W; Wu Q; Zhang K; Li Y; Xiang JN; Elliott JD; Leung S; Ren F; Lin X Bioorg Med Chem; 2015 Sep; 23(17):5293-302. PubMed ID: 26277758 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]