191 related articles for article (PubMed ID: 27379713)
1. Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
Brunner K; Maric S; Reshma RS; Almqvist H; Seashore-Ludlow B; Gustavsson AL; Poyraz Ö; Yogeeswari P; Lundbäck T; Vallin M; Sriram D; Schnell R; Schneider G
J Med Chem; 2016 Jul; 59(14):6848-59. PubMed ID: 27379713
[TBL] [Abstract][Full Text] [Related]
2. Profiling of in vitro activities of urea-based inhibitors against cysteine synthases from Mycobacterium tuberculosis.
Brunner K; Steiner EM; Reshma RS; Sriram D; Schnell R; Schneider G
Bioorg Med Chem Lett; 2017 Oct; 27(19):4582-4587. PubMed ID: 28882483
[TBL] [Abstract][Full Text] [Related]
3. Discovery of novel inhibitors targeting the Mycobacterium tuberculosis O-acetylserine sulfhydrylase (CysK1) using virtual high-throughput screening.
Jean Kumar VU; Poyraz Ö; Saxena S; Schnell R; Yogeeswari P; Schneider G; Sriram D
Bioorg Med Chem Lett; 2013 Mar; 23(5):1182-6. PubMed ID: 23391589
[TBL] [Abstract][Full Text] [Related]
4. Structure-guided design of novel thiazolidine inhibitors of O-acetyl serine sulfhydrylase from Mycobacterium tuberculosis.
Poyraz O; Jeankumar VU; Saxena S; Schnell R; Haraldsson M; Yogeeswari P; Sriram D; Schneider G
J Med Chem; 2013 Aug; 56(16):6457-66. PubMed ID: 23879381
[TBL] [Abstract][Full Text] [Related]
5. Identification and structure-activity relationship study of carvacrol derivatives as Mycobacterium tuberculosis chorismate mutase inhibitors.
Alokam R; Jeankumar VU; Sridevi JP; Matikonda SS; Peddi S; Alvala M; Yogeeswari P; Sriram D
J Enzyme Inhib Med Chem; 2014 Aug; 29(4):547-54. PubMed ID: 24090423
[TBL] [Abstract][Full Text] [Related]
6. Pyridoxal-phosphate dependent mycobacterial cysteine synthases: Structure, mechanism and potential as drug targets.
Schnell R; Sriram D; Schneider G
Biochim Biophys Acta; 2015 Sep; 1854(9):1175-83. PubMed ID: 25484279
[TBL] [Abstract][Full Text] [Related]
7. Cysteine synthase (CysM) of Mycobacterium tuberculosis is an O-phosphoserine sulfhydrylase: evidence for an alternative cysteine biosynthesis pathway in mycobacteria.
Agren D; Schnell R; Oehlmann W; Singh M; Schneider G
J Biol Chem; 2008 Nov; 283(46):31567-74. PubMed ID: 18799456
[TBL] [Abstract][Full Text] [Related]
8. Refining the structure-activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms.
Magalhães J; Franko N; Annunziato G; Pieroni M; Benoni R; Nikitjuka A; Mozzarelli A; Bettati S; Karawajczyk A; Jirgensons A; Campanini B; Costantino G
J Enzyme Inhib Med Chem; 2019 Dec; 34(1):31-43. PubMed ID: 30362368
[TBL] [Abstract][Full Text] [Related]
9. CysK2 from Mycobacterium tuberculosis is an O-phospho-L-serine-dependent S-sulfocysteine synthase.
Steiner EM; Böth D; Lössl P; Vilaplana F; Schnell R; Schneider G
J Bacteriol; 2014 Oct; 196(19):3410-20. PubMed ID: 25022854
[TBL] [Abstract][Full Text] [Related]
10. Discovery and development of the covalent hydrates of trifluoromethylated pyrazoles as riboflavin synthase inhibitors with antibiotic activity against Mycobacterium tuberculosis.
Zhao Y; Bacher A; Illarionov B; Fischer M; Georg G; Ye QZ; Fanwick PE; Franzblau SG; Wan B; Cushman M
J Org Chem; 2009 Aug; 74(15):5297-303. PubMed ID: 19545132
[TBL] [Abstract][Full Text] [Related]
11. Antimycobacterial activity of UDP-galactopyranose mutase inhibitors.
Borrelli S; Zandberg WF; Mohan S; Ko M; Martinez-Gutierrez F; Partha SK; Sanders DA; Av-Gay Y; Pinto BM
Int J Antimicrob Agents; 2010 Oct; 36(4):364-8. PubMed ID: 20678902
[TBL] [Abstract][Full Text] [Related]
12. In vitro and ex vivo activity of new derivatives of acetohydroxyacid synthase inhibitors against Mycobacterium tuberculosis and non-tuberculous mycobacteria.
Sohn H; Lee KS; Ko YK; Ryu JW; Woo JC; Koo DW; Shin SJ; Ahn SJ; Shin AR; Song CH; Jo EK; Park JK; Kim HJ
Int J Antimicrob Agents; 2008 Jun; 31(6):567-71. PubMed ID: 18337064
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis and biological evaluation of imidazo[2,1-b]thiazole and benzo[d]imidazo[2,1-b]thiazole derivatives as Mycobacterium tuberculosis pantothenate synthetase inhibitors.
Samala G; Devi PB; Saxena S; Meda N; Yogeeswari P; Sriram D
Bioorg Med Chem; 2016 Mar; 24(6):1298-307. PubMed ID: 26867485
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth.
Chollet A; Mori G; Menendez C; Rodriguez F; Fabing I; Pasca MR; Madacki J; Korduláková J; Constant P; Quémard A; Bernardes-Génisson V; Lherbet C; Baltas M
Eur J Med Chem; 2015 Aug; 101():218-35. PubMed ID: 26142487
[TBL] [Abstract][Full Text] [Related]
15. The C-terminal of CysM from Mycobacterium tuberculosis protects the aminoacrylate intermediate and is involved in sulfur donor selectivity.
Agren D; Schnell R; Schneider G
FEBS Lett; 2009 Jan; 583(2):330-6. PubMed ID: 19101553
[TBL] [Abstract][Full Text] [Related]
16. Identification and development of benzoxazole derivatives as novel bacterial glutamate racemase inhibitors.
Malapati P; Krishna VS; Nallangi R; Srilakshmi RR; Sriram D
Eur J Med Chem; 2018 Feb; 145():23-34. PubMed ID: 29310027
[TBL] [Abstract][Full Text] [Related]
17. Identification of novel antimycobacterial chemical agents through the in silico multi-conformational structure-based drug screening of a large-scale chemical library.
Koseki Y; Kinjo T; Kobayashi M; Aoki S
Eur J Med Chem; 2013 Feb; 60():333-9. PubMed ID: 23314046
[TBL] [Abstract][Full Text] [Related]
18. In silico discovery and in vitro activity of inhibitors against
Billones JB; Carrillo MC; Organo VG; Sy JB; Clavio NA; Macalino SJ; Emnacen IA; Lee AP; Ko PK; Concepcion GP
Drug Des Devel Ther; 2017; 11():563-574. PubMed ID: 28280303
[TBL] [Abstract][Full Text] [Related]
19. Identification of Bostrycin Derivatives as Potential Inhibitors of Mycobacterium tuberculosis Protein Tyrosine Phosphatase (MptpB).
Chen DN; Chen H; She ZG; Lu YJ
Med Chem; 2016; 12(3):296-302. PubMed ID: 26434800
[TBL] [Abstract][Full Text] [Related]
20. Substrate Fragmentation for the Design of M. tuberculosis CYP121 Inhibitors.
Kavanagh ME; Gray JL; Gilbert SH; Coyne AG; McLean KJ; Davis HJ; Munro AW; Abell C
ChemMedChem; 2016 Sep; 11(17):1924-35. PubMed ID: 27432475
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]