220 related articles for article (PubMed ID: 27380369)
1. Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum.
Lunev S; Bosch SS; Batista Fde A; Wrenger C; Groves MR
Acta Crystallogr F Struct Biol Commun; 2016 Jul; 72(Pt 7):523-33. PubMed ID: 27380369
[TBL] [Abstract][Full Text] [Related]
2. Identification of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase.
Lunev S; Bosch SS; Batista FA; Wang C; Li J; Linzke M; Kruithof P; Chamoun G; Dömling ASS; Wrenger C; Groves MR
Biochem Biophys Res Commun; 2018 Mar; 497(3):835-842. PubMed ID: 29476738
[TBL] [Abstract][Full Text] [Related]
3. Novel Highlight in Malarial Drug Discovery: Aspartate Transcarbamoylase.
Wang C; Krüger A; Du X; Wrenger C; Groves MR
Front Cell Infect Microbiol; 2022; 12():841833. PubMed ID: 35310840
[TBL] [Abstract][Full Text] [Related]
4. Charge neutralization in the active site of the catalytic trimer of aspartate transcarbamoylase promotes diverse structural changes.
Endrizzi JA; Beernink PT
Protein Sci; 2017 Nov; 26(11):2221-2228. PubMed ID: 28833948
[TBL] [Abstract][Full Text] [Related]
5. Expression, purification, crystallization and preliminary X-ray diffraction analysis of the aspartate transcarbamoylase domain of human CAD.
Ruiz-Ramos A; Lallous N; Grande-García A; Ramón-Maiques S
Acta Crystallogr Sect F Struct Biol Cryst Commun; 2013 Dec; 69(Pt 12):1425-30. PubMed ID: 24316846
[TBL] [Abstract][Full Text] [Related]
6. Crystal structure of Plasmodium falciparum proplasmepsin IV: the plasticity of proplasmepsins.
Recacha R; Jaudzems K; Akopjana I; Jirgensons A; Tars K
Acta Crystallogr F Struct Biol Commun; 2016 Sep; 72(Pt 9):659-66. PubMed ID: 27599854
[TBL] [Abstract][Full Text] [Related]
7. Molecular Target Validation of Aspartate Transcarbamoylase from
Bosch SS; Lunev S; Batista FA; Linzke M; Kronenberger T; Dömling ASS; Groves MR; Wrenger C
ACS Infect Dis; 2020 May; 6(5):986-999. PubMed ID: 32129597
[TBL] [Abstract][Full Text] [Related]
8. A 70-amino acid zinc-binding polypeptide fragment from the regulatory chain of aspartate transcarbamoylase causes marked changes in the kinetic mechanism of the catalytic trimer.
Zhou BB; Waldrop GL; Lum L; Schachman HK
Protein Sci; 1994 Jun; 3(6):967-74. PubMed ID: 8069226
[TBL] [Abstract][Full Text] [Related]
9. Weakening of the interface between adjacent catalytic chains promotes domain closure in Escherichia coli aspartate transcarbamoylase.
Baker DP; Fetler L; Keiser RT; Vachette P; Kantrowitz ER
Protein Sci; 1995 Feb; 4(2):258-67. PubMed ID: 7757014
[TBL] [Abstract][Full Text] [Related]
10. Importance of a conserved residue, aspartate-162, for the function of Escherichia coli aspartate transcarbamoylase.
Newton CJ; Stevens RC; Kantrowitz ER
Biochemistry; 1992 Mar; 31(11):3026-32. PubMed ID: 1550826
[TBL] [Abstract][Full Text] [Related]
11. Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis.
Moreno-Morcillo M; Grande-García A; Ruiz-Ramos A; Del Caño-Ochoa F; Boskovic J; Ramón-Maiques S
Structure; 2017 Jun; 25(6):912-923.e5. PubMed ID: 28552578
[TBL] [Abstract][Full Text] [Related]
12. Active site metals mediate an oligomeric equilibrium in Plasmodium M17 aminopeptidases.
Malcolm TR; Belousoff MJ; Venugopal H; Borg NA; Drinkwater N; Atkinson SC; McGowan S
J Biol Chem; 2021; 296():100173. PubMed ID: 33303633
[TBL] [Abstract][Full Text] [Related]
13. Overexpression and purification of the trimeric aspartate transcarbamoylase from Bacillus subtilis.
Baker DP; Aucoin JM; Williams MK; deMello LA; Kantrowitz ER
Protein Expr Purif; 1995 Oct; 6(5):679-84. PubMed ID: 8535162
[TBL] [Abstract][Full Text] [Related]
14. Structure of the catalytic chain of Methanococcus jannaschii aspartate transcarbamoylase in a hexagonal crystal form: insights into the path of carbamoyl phosphate to the active site of the enzyme.
Vitali J; Singh AK; Soares AS; Colaneri MJ
Acta Crystallogr Sect F Struct Biol Cryst Commun; 2012 May; 68(Pt 5):527-34. PubMed ID: 22691781
[TBL] [Abstract][Full Text] [Related]
15. A single amino acid substitution in the active site of Escherichia coli aspartate transcarbamoylase prevents the allosteric transition.
Stieglitz KA; Pastra-Landis SC; Xia J; Tsuruta H; Kantrowitz ER
J Mol Biol; 2005 Jun; 349(2):413-23. PubMed ID: 15890205
[TBL] [Abstract][Full Text] [Related]
16. Structure of a fungal form of aspartate-semialdehyde dehydrogenase from Aspergillus fumigatus.
Dahal GP; Viola RE
Acta Crystallogr F Struct Biol Commun; 2017 Jan; 73(Pt 1):36-44. PubMed ID: 28045392
[TBL] [Abstract][Full Text] [Related]
17. Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase.
Bellin L; Del Caño-Ochoa F; Velázquez-Campoy A; Möhlmann T; Ramón-Maiques S
Nat Commun; 2021 Feb; 12(1):947. PubMed ID: 33574254
[TBL] [Abstract][Full Text] [Related]
18. An alternative mechanism for the methylation of phosphoethanolamine catalyzed by Plasmodium falciparum phosphoethanolamine methyltransferase.
Saen-Oon S; Lee SG; Jez JM; Guallar V
J Biol Chem; 2014 Dec; 289(49):33815-25. PubMed ID: 25288796
[TBL] [Abstract][Full Text] [Related]
19. Aspartate transcarbamylase from the hyperthermophilic archaeon Pyrococcus abyssi: thermostability and 1.8A resolution crystal structure of the catalytic subunit complexed with the bisubstrate analogue N-phosphonacetyl-L-aspartate.
Van Boxstael S; Cunin R; Khan S; Maes D
J Mol Biol; 2003 Feb; 326(1):203-16. PubMed ID: 12547202
[TBL] [Abstract][Full Text] [Related]
20. Function of threonine-55 in the carbamoyl phosphate binding site of Escherichia coli aspartate transcarbamoylase.
Xu W; Kantrowitz ER
Biochemistry; 1989 Dec; 28(26):9937-43. PubMed ID: 2515892
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
