These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

339 related articles for article (PubMed ID: 27387538)

  • 1. Enantioselective inhibition of Cytochrome P450-mediated drug metabolism by a novel antithrombotic agent, S002-333: Major effect on CYP2B6.
    Bhateria M; Ramakrishna R; Puttrevu SK; Saxena AK; Bhatta RS
    Chem Biol Interact; 2016 Aug; 256():257-65. PubMed ID: 27387538
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In vitro metabolism of a novel antithrombotic compound, S002-333, and its enantiomers: quantitative cytochrome P450 phenotyping, metabolic profiling and enzyme kinetic studies.
    Saxena A; Jain GK; Siddiqui HH; Bhunia SS; Saxena AK; Gayen JR
    Xenobiotica; 2014 Apr; 44(4):295-308. PubMed ID: 23992115
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insight into stereoselective disposition of enantiomers of a potent antithrombotic agent, S002-333 following administration of the racemic compound to mice.
    Bhateria M; Rachumallu R; Yerrabelli S; Saxena AK; Bhatta RS
    Eur J Pharm Sci; 2017 Apr; 101():107-114. PubMed ID: 28189817
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabolic profiling of a novel antithrombotic compound, S002-333 and enantiomers: metabolic stability, species comparison and in vitro-in vivo extrapolation.
    Saxena A; Valicherla GR; Jain GK; Bhatta RS; Saxena AK; Gayen JR
    Biopharm Drug Dispos; 2016 May; 37(4):185-99. PubMed ID: 26477787
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potent inhibition of cytochrome P450 2B6 by sibutramine in human liver microsomes.
    Bae SH; Kwon MJ; Choi EJ; Zheng YF; Yoon KD; Liu KH; Bae SK
    Chem Biol Interact; 2013 Sep; 205(1):11-9. PubMed ID: 23777987
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stereo-selective metabolism of methadone by human liver microsomes and cDNA-expressed cytochrome P450s: a reconciliation.
    Chang Y; Fang WB; Lin SN; Moody DE
    Basic Clin Pharmacol Toxicol; 2011 Jan; 108(1):55-62. PubMed ID: 20825389
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions.
    Liu S; Wang Z; Chan E; Zhao Y; Kang J; Zhang X; Tian X
    Chem Biol Interact; 2022 Jan; 352():109775. PubMed ID: 34910929
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evaluation of metabolism dependent inhibition of CYP2B6 mediated bupropion hydroxylation in human liver microsomes by monoamine oxidase inhibitors and prediction of potential as perpetrators of drug interaction.
    Nirogi R; Palacharla RC; Mohammed AR; Manoharan A; Ponnamaneni RK; Bhyrapuneni G
    Chem Biol Interact; 2015 Mar; 230():9-20. PubMed ID: 25656918
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NADPH-Independent Inactivation of CYP2B6 and NADPH-Dependent Inactivation of CYP3A4/5 by PBD: Potential Implication for Assessing Covalent Modulators for Time-Dependent Inhibition.
    Kosaka M; Zhang D; Wong S; Yan Z
    Drug Metab Dispos; 2020 Aug; 48(8):655-661. PubMed ID: 32482757
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19.
    Gerber JG; Rhodes RJ; Gal J
    Chirality; 2004 Jan; 16(1):36-44. PubMed ID: 14628297
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stereoselective metabolism of ifosfamide by human P-450s 3A4 and 2B6. Favorable metabolic properties of R-enantiomer.
    Roy P; Tretyakov O; Wright J; Waxman DJ
    Drug Metab Dispos; 1999 Nov; 27(11):1309-18. PubMed ID: 10534317
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enzyme Kinetics and Molecular Docking Studies on Cytochrome 2B6, 2C19, 2E1, and 3A4 Activities by Sauchinone.
    Gong EC; Chea S; Balupuri A; Kang NS; Chin YW; Choi YH
    Molecules; 2018 Mar; 23(3):. PubMed ID: 29498658
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of human cytochrome P450 isoforms involved in the stereoselective metabolism of mianserin enantiomers.
    Koyama E; Chiba K; Tani M; Ishizaki T
    J Pharmacol Exp Ther; 1996 Jul; 278(1):21-30. PubMed ID: 8764331
    [TBL] [Abstract][Full Text] [Related]  

  • 14. AM-2201 Inhibits Multiple Cytochrome P450 and Uridine 5'-Diphospho-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes.
    Kim JH; Kwon SS; Kong TY; Cheong JC; Kim HS; In MK; Lee HS
    Molecules; 2017 Mar; 22(3):. PubMed ID: 28287454
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evaluation of In Vitro Cytochrome P450 Inhibition and In Vitro Fate of Structurally Diverse N-Oxide Metabolites: Case Studies with Clozapine, Levofloxacin, Roflumilast, Voriconazole and Zopiclone.
    Giri P; Naidu S; Patel N; Patel H; Srinivas NR
    Eur J Drug Metab Pharmacokinet; 2017 Aug; 42(4):677-688. PubMed ID: 27853934
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of cytochrome P450 enzymes involved in ketamine metabolism by use of liver microsomes and specific cytochrome P450 enzymes from horses, dogs, and humans.
    Mössner LD; Schmitz A; Theurillat R; Thormann W; Mevissen M
    Am J Vet Res; 2011 Nov; 72(11):1505-13. PubMed ID: 22023129
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selective inhibitory effects of machilin A isolated from Machilus thunbergii on human cytochrome P450 1A and 2B6.
    Kim SJ; You J; Choi HG; Kim JA; Jee JG; Lee S
    Phytomedicine; 2015 Jun; 22(6):615-20. PubMed ID: 26055126
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stereoselective interaction between tetrahydropalmatine enantiomers and CYP enzymes in human liver microsomes.
    Sun SY; Wang YQ; Li LP; Wang L; Zeng S; Zhou H; Jiang HD
    Chirality; 2013 Jan; 25(1):43-7. PubMed ID: 23001793
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of green tea catechins on cytochrome P450 2B6, 2C8, 2C19, 2D6 and 3A activities in human liver and intestinal microsomes.
    Misaka S; Kawabe K; Onoue S; Werba JP; Giroli M; Tamaki S; Kan T; Kimura J; Watanabe H; Yamada S
    Drug Metab Pharmacokinet; 2013; 28(3):244-9. PubMed ID: 23268924
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    Li J; Wen H; Gao Z
    Xenobiotica; 2020 Feb; 50(2):231-236. PubMed ID: 31020909
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.