BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 27396339)

  • 1. Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development.
    Barrett NA; Malouf C; Kapeni C; Bacon WA; Giotopoulos G; Jacobsen SEW; Huntly BJ; Ottersbach K
    Cell Rep; 2016 Jul; 16(4):1039-1054. PubMed ID: 27396339
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The full transforming capacity of MLL-Af4 is interlinked with lymphoid lineage commitment.
    Lin S; Luo RT; Shrestha M; Thirman MJ; Mulloy JC
    Blood; 2017 Aug; 130(7):903-907. PubMed ID: 28637661
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of MEK and ATR is effective in a B-cell acute lymphoblastic leukemia model driven by
    Chu SH; Song EJ; Chabon JR; Minehart J; Matovina CN; Makofske JL; Frank ES; Ross K; Koche RP; Feng Z; Xu H; Krivtsov A; Nussenzweig A; Armstrong SA
    Blood Adv; 2018 Oct; 2(19):2478-2490. PubMed ID: 30266823
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The AF4.MLL fusion protein is capable of inducing ALL in mice without requirement of MLL.AF4.
    Bursen A; Schwabe K; Rüster B; Henschler R; Ruthardt M; Dingermann T; Marschalek R
    Blood; 2010 Apr; 115(17):3570-9. PubMed ID: 20194896
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Instructive Role of MLL-Fusion Proteins Revealed by a Model of t(4;11) Pro-B Acute Lymphoblastic Leukemia.
    Lin S; Luo RT; Ptasinska A; Kerry J; Assi SA; Wunderlich M; Imamura T; Kaberlein JJ; Rayes A; Althoff MJ; Anastasi J; O'Brien MM; Meetei AR; Milne TA; Bonifer C; Mulloy JC; Thirman MJ
    Cancer Cell; 2016 Nov; 30(5):737-749. PubMed ID: 27846391
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Leukemic fusion genes MLL/AF4 and AML1/MTG8 support leukemic self-renewal by controlling expression of the telomerase subunit TERT.
    Gessner A; Thomas M; Castro PG; Büchler L; Scholz A; Brümmendorf TH; Soria NM; Vormoor J; Greil J; Heidenreich O
    Leukemia; 2010 Oct; 24(10):1751-9. PubMed ID: 20686504
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enforced expression of MLL-AF4 fusion in cord blood CD34+ cells enhances the hematopoietic repopulating cell function and clonogenic potential but is not sufficient to initiate leukemia.
    Montes R; Ayllón V; Gutierrez-Aranda I; Prat I; Hernández-Lamas MC; Ponce L; Bresolin S; Te Kronnie G; Greaves M; Bueno C; Menendez P
    Blood; 2011 May; 117(18):4746-58. PubMed ID: 21389315
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fetal liver Mll-AF4+ hematopoietic stem and progenitor cells respond directly to poly(I:C), but not to a single maternal immune activation.
    Malouf C; Ottersbach K
    Exp Hematol; 2019 Aug; 76():49-59. PubMed ID: 31381950
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting MLL-AF4 with short interfering RNAs inhibits clonogenicity and engraftment of t(4;11)-positive human leukemic cells.
    Thomas M; Gessner A; Vornlocher HP; Hadwiger P; Greil J; Heidenreich O
    Blood; 2005 Nov; 106(10):3559-66. PubMed ID: 16046533
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pro-B-cell to pre-B-cell development in B-lineage acute lymphoblastic leukemia expressing the MLL/AF4 fusion protein.
    Bertrand FE; Vogtenhuber C; Shah N; LeBien TW
    Blood; 2001 Dec; 98(12):3398-405. PubMed ID: 11719380
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification.
    Bueno C; Montes R; Melen GJ; Ramos-Mejia V; Real PJ; Ayllón V; Sanchez L; Ligero G; Gutierrez-Aranda I; Fernández AF; Fraga MF; Moreno-Gimeno I; Burks D; Plaza-Calonge Mdel C; Rodríguez-Manzaneque JC; Menendez P
    Cell Res; 2012 Jun; 22(6):986-1002. PubMed ID: 22212479
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insights into the cellular origin and etiology of the infant pro-B acute lymphoblastic leukemia with MLL-AF4 rearrangement.
    Bueno C; Montes R; Catalina P; Rodríguez R; Menendez P
    Leukemia; 2011 Mar; 25(3):400-10. PubMed ID: 21135858
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A murine Mll-AF4 knock-in model results in lymphoid and myeloid deregulation and hematologic malignancy.
    Chen W; Li Q; Hudson WA; Kumar A; Kirchhof N; Kersey JH
    Blood; 2006 Jul; 108(2):669-77. PubMed ID: 16551973
    [TBL] [Abstract][Full Text] [Related]  

  • 14. FLT3 activation cooperates with MLL-AF4 fusion protein to abrogate the hematopoietic specification of human ESCs.
    Bueno C; Ayllón V; Montes R; Navarro-Montero O; Ramos-Mejia V; Real PJ; Romero-Moya D; Araúzo-Bravo MJ; Menendez P
    Blood; 2013 May; 121(19):3867-78, S1-3. PubMed ID: 23479570
    [TBL] [Abstract][Full Text] [Related]  

  • 15. circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression.
    Huang W; Fang K; Chen TQ; Zeng ZC; Sun YM; Han C; Sun LY; Chen ZH; Yang QQ; Pan Q; Luo XQ; Wang WT; Chen YQ
    J Hematol Oncol; 2019 Oct; 12(1):103. PubMed ID: 31623653
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Combined effects of the two reciprocal t(4;11) fusion proteins MLL.AF4 and AF4.MLL confer resistance to apoptosis, cell cycling capacity and growth transformation.
    Gaussmann A; Wenger T; Eberle I; Bursen A; Bracharz S; Herr I; Dingermann T; Marschalek R
    Oncogene; 2007 May; 26(23):3352-63. PubMed ID: 17130830
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crosstalk between 14-3-3θ and AF4 enhances MLL-AF4 activity and promotes leukemia cell proliferation.
    Fioretti T; Cevenini A; Zanobio M; Raia M; Sarnataro D; Salvatore F; Esposito G
    Cell Oncol (Dordr); 2019 Dec; 42(6):829-845. PubMed ID: 31493143
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nuclear FGFR2 Interacts with the MLL-AF4 Oncogenic Chimera and Positively Regulates
    Fioretti T; Cevenini A; Zanobio M; Raia M; Sarnataro D; Cattaneo F; Ammendola R; Esposito G
    Int J Mol Sci; 2021 Apr; 22(9):. PubMed ID: 33924850
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Leukemogenic pathway of infant leukemia with MLL fusion].
    Eguchi M
    Rinsho Ketsueki; 2021; 62(7):809-819. PubMed ID: 34349066
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The fetal liver lymphoid-primed multipotent progenitor provides the prerequisites for the initiation of t(4;11)
    Malouf C; Ottersbach K
    Haematologica; 2018 Dec; 103(12):e571-e574. PubMed ID: 29903765
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 10.