200 related articles for article (PubMed ID: 27398798)
1. Real-Time Biological Annotation of Synthetic Compounds.
Gerry CJ; Hua BK; Wawer MJ; Knowles JP; Nelson SD; Verho O; Dandapani S; Wagner BK; Clemons PA; Booker-Milburn KI; Boskovic ZV; Schreiber SL
J Am Chem Soc; 2016 Jul; 138(28):8920-7. PubMed ID: 27398798
[TBL] [Abstract][Full Text] [Related]
2. DNA-encoded chemical libraries: advancing beyond conventional small-molecule libraries.
Franzini RM; Neri D; Scheuermann J
Acc Chem Res; 2014 Apr; 47(4):1247-55. PubMed ID: 24673190
[TBL] [Abstract][Full Text] [Related]
3. Customizable Generation of Synthetically Accessible, Local Chemical Subspaces.
Pottel J; Moitessier N
J Chem Inf Model; 2017 Mar; 57(3):454-467. PubMed ID: 28234470
[TBL] [Abstract][Full Text] [Related]
4. Direct Phenotypic Screening in Mice: Identification of Individual, Novel Antinociceptive Compounds from a Library of 734,821 Pyrrolidine Bis-piperazines.
Houghten RA; Ganno ML; McLaughlin JP; Dooley CT; Eans SO; Santos RG; LaVoi T; Nefzi A; Welmaker G; Giulianotti MA; Toll L
ACS Comb Sci; 2016 Jan; 18(1):51-64. PubMed ID: 26651386
[TBL] [Abstract][Full Text] [Related]
5. Connecting synthetic chemistry decisions to cell and genome biology using small-molecule phenotypic profiling.
Wagner BK; Clemons PA
Curr Opin Chem Biol; 2009 Dec; 13(5-6):539-48. PubMed ID: 19825513
[TBL] [Abstract][Full Text] [Related]
6. Synergistic Effects of Stereochemistry and Appendages on the Performance Diversity of a Collection of Synthetic Compounds.
Melillo B; Zoller J; Hua BK; Verho O; Borghs JC; Nelson SD; Maetani M; Wawer MJ; Clemons PA; Schreiber SL
J Am Chem Soc; 2018 Sep; 140(37):11784-11790. PubMed ID: 30133283
[TBL] [Abstract][Full Text] [Related]
7. Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling.
Wawer MJ; Li K; Gustafsdottir SM; Ljosa V; Bodycombe NE; Marton MA; Sokolnicki KL; Bray MA; Kemp MM; Winchester E; Taylor B; Grant GB; Hon CS; Duvall JR; Wilson JA; Bittker JA; Dančík V; Narayan R; Subramanian A; Winckler W; Golub TR; Carpenter AE; Shamji AF; Schreiber SL; Clemons PA
Proc Natl Acad Sci U S A; 2014 Jul; 111(30):10911-6. PubMed ID: 25024206
[TBL] [Abstract][Full Text] [Related]
8. Molecular library design using multi-objective optimization methods.
Nicolaou CA; Kannas CC
Methods Mol Biol; 2011; 685():53-69. PubMed ID: 20981518
[TBL] [Abstract][Full Text] [Related]
9. Next generation diversity-oriented synthesis: a paradigm shift from chemical diversity to biological diversity.
Pavlinov I; Gerlach EM; Aldrich LN
Org Biomol Chem; 2019 Feb; 17(7):1608-1623. PubMed ID: 30328455
[TBL] [Abstract][Full Text] [Related]
10. Privileged structures: efficient chemical "navigators" toward unexplored biologically relevant chemical spaces.
Kim J; Kim H; Park SB
J Am Chem Soc; 2014 Oct; 136(42):14629-38. PubMed ID: 25310802
[TBL] [Abstract][Full Text] [Related]
11. Molecular complexity and fragment-based drug discovery: ten years on.
Leach AR; Hann MM
Curr Opin Chem Biol; 2011 Aug; 15(4):489-96. PubMed ID: 21665521
[TBL] [Abstract][Full Text] [Related]
12. The Evolution of DNA-Templated Synthesis as a Tool for Materials Discovery.
O'Reilly RK; Turberfield AJ; Wilks TR
Acc Chem Res; 2017 Oct; 50(10):2496-2509. PubMed ID: 28915003
[TBL] [Abstract][Full Text] [Related]
13. Employing Photocatalysis for the Design and Preparation of DNA-Encoded Libraries: A Case Study.
Kölmel DK; Zhu H; Flanagan ME; Sakata SK; Harris AR; Wan J; Morgan BA
Chem Rec; 2021 Apr; 21(4):616-630. PubMed ID: 33570227
[TBL] [Abstract][Full Text] [Related]
14. Efficient three-step one-pot synthesis of a novel 2,3,5-substituted pyrazine library.
Delvare C; Harris CS; Hennequin L; Koza P; Lambert-van der Brempt C; Pelleter J; Willerval O
ACS Comb Sci; 2011 Sep; 13(5):449-52. PubMed ID: 21648463
[TBL] [Abstract][Full Text] [Related]
15. Smart Design of Small-Molecule Libraries: When Organic Synthesis Meets Cheminformatics.
Lenci E; Trabocchi A
Chembiochem; 2019 May; 20(9):1115-1123. PubMed ID: 30589187
[TBL] [Abstract][Full Text] [Related]
16. Tractable synthesis of multipurpose screening compounds with under-represented molecular features for an open access screening platform.
Wilde F; Specker E; Neuenschwander M; Nazaré M; Bodtke A; Link A
Mol Divers; 2014 Aug; 18(3):483-95. PubMed ID: 24687389
[TBL] [Abstract][Full Text] [Related]
17. Automated radial synthesis of organic molecules.
Chatterjee S; Guidi M; Seeberger PH; Gilmore K
Nature; 2020 Mar; 579(7799):379-384. PubMed ID: 32188949
[TBL] [Abstract][Full Text] [Related]
18. Morphological subprofile analysis for bioactivity annotation of small molecules.
Pahl A; Schölermann B; Lampe P; Rusch M; Dow M; Hedberg C; Nelson A; Sievers S; Waldmann H; Ziegler S
Cell Chem Biol; 2023 Jul; 30(7):839-853.e7. PubMed ID: 37385259
[TBL] [Abstract][Full Text] [Related]
19. Access to a Structurally Complex Compound Collection via Ring Distortion of the Alkaloid Sinomenine.
Garcia A; Drown BS; Hergenrother PJ
Org Lett; 2016 Oct; 18(19):4852-4855. PubMed ID: 27650404
[TBL] [Abstract][Full Text] [Related]
20. Drug discovery: A question of library design.
Hajduk PJ; Galloway WR; Spring DR
Nature; 2011 Feb; 470(7332):42-3. PubMed ID: 21293363
[No Abstract] [Full Text] [Related]
[Next] [New Search]
