105 related articles for article (PubMed ID: 27404508)
1. Product Release Pathways in Human and Plasmodium falciparum Phosphoribosyltransferase.
Karmakar T; Roy S; Balaram H; Prakash MK; Balasubramanian S
J Chem Inf Model; 2016 Aug; 56(8):1528-38. PubMed ID: 27404508
[TBL] [Abstract][Full Text] [Related]
2. Role of W181 in modulating kinetic properties of Plasmodium falciparum hypoxanthine guanine xanthine phosphoribosyltransferase.
Roy S; Karmakar T; Nagappa LK; Prahlada Rao VS; Balasubramanian S; Balaram H
Proteins; 2016 Nov; 84(11):1658-1669. PubMed ID: 27479359
[TBL] [Abstract][Full Text] [Related]
3. Slow ligand-induced conformational switch increases the catalytic rate in Plasmodium falciparum hypoxanthine guanine xanthine phosphoribosyltransferase.
Roy S; Karmakar T; Prahlada Rao VS; Nagappa LK; Balasubramanian S; Balaram H
Mol Biosyst; 2015 May; 11(5):1410-24. PubMed ID: 25824378
[TBL] [Abstract][Full Text] [Related]
4. Kinetic mechanism of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.
Roy S; Nagappa LK; Prahladarao VS; Balaram H
Mol Biochem Parasitol; 2015 Dec; 204(2):111-120. PubMed ID: 26902413
[TBL] [Abstract][Full Text] [Related]
5. Plasmodium falciparum hypoxanthine guanine phosphoribosyltransferase. Stability studies on the product-activated enzyme.
Raman J; Ashok CS; Subbayya SI; Anand RP; Selvi ST; Balaram H
FEBS J; 2005 Apr; 272(8):1900-11. PubMed ID: 15819884
[TBL] [Abstract][Full Text] [Related]
6. Unusual substrate specificity of a chimeric hypoxanthine-guanine phosphoribosyltransferase containing segments from the Plasmodium falciparum and human enzymes.
Sujay Subbayya IN; Sukumaran S; Shivashankar K; Balaram H
Biochem Biophys Res Commun; 2000 Jun; 272(2):596-602. PubMed ID: 10833458
[TBL] [Abstract][Full Text] [Related]
7. Alternative IMP binding in feedback inhibition of hypoxanthine-guanine phosphoribosyltransferase from Thermoanaerobacter tengcongensis.
Chen Q; Liang Y; Su X; Gu X; Zheng X; Luo M
J Mol Biol; 2005 May; 348(5):1199-210. PubMed ID: 15854655
[TBL] [Abstract][Full Text] [Related]
8. Acidic residues in the purine binding site govern the 6-oxopurine specificity of the Leishmania donovani xanthine phosphoribosyltransferase.
Ullman B; Cyr N; Choi K; Jardim A
Int J Biochem Cell Biol; 2010 Feb; 42(2):253-62. PubMed ID: 19861168
[TBL] [Abstract][Full Text] [Related]
9. Structural and dynamical correlations in PfHGXPRT oligomers: A molecular dynamics simulation study.
Karmakar T; Roy S; Balaram H; Balasubramanian S
J Biomol Struct Dyn; 2016 Jul; 34(7):1590-605. PubMed ID: 26441001
[TBL] [Abstract][Full Text] [Related]
10. Synthesis of purine N9-[2-hydroxy-3-O-(phosphonomethoxy)propyl] derivatives and their side-chain modified analogs as potential antimalarial agents.
Krečmerová M; Dračínský M; Hocková D; Holý A; Keough DT; Guddat LW
Bioorg Med Chem; 2012 Feb; 20(3):1222-30. PubMed ID: 22249123
[TBL] [Abstract][Full Text] [Related]
11. Design of Plasmodium vivax Hypoxanthine-Guanine Phosphoribosyltransferase Inhibitors as Potential Antimalarial Therapeutics.
Keough DT; Rejman D; Pohl R; Zborníková E; Hocková D; Croll T; Edstein MD; Birrell GW; Chavchich M; Naesens LMJ; Pierens GK; Brereton IM; Guddat LW
ACS Chem Biol; 2018 Jan; 13(1):82-90. PubMed ID: 29161011
[TBL] [Abstract][Full Text] [Related]
12. Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate.
Gogia S; Balaram H; Puranik M
Biochemistry; 2011 May; 50(19):4184-93. PubMed ID: 21486037
[TBL] [Abstract][Full Text] [Related]
13. Synthesis of branched 9-[2-(2-phosphonoethoxy)ethyl]purines as a new class of acyclic nucleoside phosphonates which inhibit Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.
Hocková D; Holý A; Masojídková M; Keough DT; de Jersey J; Guddat LW
Bioorg Med Chem; 2009 Sep; 17(17):6218-32. PubMed ID: 19666228
[TBL] [Abstract][Full Text] [Related]
14. A non-active site mutation in human hypoxanthine guanine phosphoribosyltransferase expands substrate specificity.
Raman J; Sumathy K; Anand RP; Balaram H
Arch Biochem Biophys; 2004 Jul; 427(1):116-22. PubMed ID: 15178494
[TBL] [Abstract][Full Text] [Related]
15. Purification and characterization of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase and comparison with the human enzyme.
Keough DT; Ng AL; Winzor DJ; Emmerson BT; de Jersey J
Mol Biochem Parasitol; 1999 Jan; 98(1):29-41. PubMed ID: 10029307
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and Evaluation of Asymmetric Acyclic Nucleoside Bisphosphonates as Inhibitors of Plasmodium falciparum and Human Hypoxanthine-Guanine-(Xanthine) Phosphoribosyltransferase.
Špaček P; Keough DT; Chavchich M; Dračínský M; Janeba Z; Naesens L; Edstein MD; Guddat LW; Hocková D
J Med Chem; 2017 Sep; 60(17):7539-7554. PubMed ID: 28813147
[TBL] [Abstract][Full Text] [Related]
17. Investigation of the functional role of active site loop II in a hypoxanthine phosphoribosyltransferase.
Lee CC; Medrano FJ; Craig SP; Eakin AE
Biochim Biophys Acta; 2001 Jul; 1537(1):63-70. PubMed ID: 11476964
[TBL] [Abstract][Full Text] [Related]
18. Steady-state kinetics of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus: the role of threonine-47.
Munagala NR; Chin MS; Wang CC
Biochemistry; 1998 Mar; 37(12):4045-51. PubMed ID: 9521725
[TBL] [Abstract][Full Text] [Related]
19. Crystal structures of free, IMP-, and GMP-bound Escherichia coli hypoxanthine phosphoribosyltransferase.
Guddat LW; Vos S; Martin JL; Keough DT; de Jersey J
Protein Sci; 2002 Jul; 11(7):1626-38. PubMed ID: 12070315
[TBL] [Abstract][Full Text] [Related]
20. Synthesis of novel N-branched acyclic nucleoside phosphonates as potent and selective inhibitors of human, Plasmodium falciparum and Plasmodium vivax 6-oxopurine phosphoribosyltransferases.
Hocková D; Keough DT; Janeba Z; Wang TH; de Jersey J; Guddat LW
J Med Chem; 2012 Jul; 55(13):6209-23. PubMed ID: 22725979
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]