BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

295 related articles for article (PubMed ID: 27407168)

  • 21. GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production.
    Herskowitz JH; Offe K; Deshpande A; Kahn RA; Levey AI; Lah JJ
    Mol Biol Cell; 2012 Jul; 23(14):2645-57. PubMed ID: 22621900
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1).
    von Einem B; Wahler A; Schips T; Serrano-Pozo A; Proepper C; Boeckers TM; Rueck A; Wirth T; Hyman BT; Danzer KM; Thal DR; von Arnim CA
    PLoS One; 2015; 10(6):e0129047. PubMed ID: 26053850
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Spatial-Temporal Mapping Reveals the Golgi as the Major Processing Site for the Pathogenic Swedish APP Mutation: Familial APP Mutant Shifts the Major APP Processing Site.
    Wang J; Gleeson PA; Fourriere L
    Traffic; 2024 Mar; 25(3):e12932. PubMed ID: 38528836
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Sorting nexin-4 regulates β-amyloid production by modulating β-site-activating cleavage enzyme-1.
    Kim NY; Cho MH; Won SH; Kang HJ; Yoon SY; Kim DH
    Alzheimers Res Ther; 2017 Jan; 9(1):4. PubMed ID: 28109317
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Decrease in brain soluble amyloid precursor protein β (sAPPβ) in Alzheimer's disease cortex.
    Wu G; Sankaranarayanan S; Hsieh SH; Simon AJ; Savage MJ
    J Neurosci Res; 2011 Jun; 89(6):822-32. PubMed ID: 21433051
    [TBL] [Abstract][Full Text] [Related]  

  • 26. A GPCR/secretase complex regulates beta- and gamma-secretase specificity for Abeta production and contributes to AD pathogenesis.
    Teng L; Zhao J; Wang F; Ma L; Pei G
    Cell Res; 2010 Feb; 20(2):138-53. PubMed ID: 20066010
    [TBL] [Abstract][Full Text] [Related]  

  • 27. CutA divalent cation tolerance homolog (Escherichia coli) (CUTA) regulates β-cleavage of β-amyloid precursor protein (APP) through interacting with β-site APP cleaving protein 1 (BACE1).
    Zhao Y; Wang Y; Hu J; Zhang X; Zhang YW
    J Biol Chem; 2012 Mar; 287(14):11141-50. PubMed ID: 22351782
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Beta-secretase (BACE) as a drug target for Alzheimer's disease.
    Vassar R
    Adv Drug Deliv Rev; 2002 Dec; 54(12):1589-602. PubMed ID: 12453676
    [TBL] [Abstract][Full Text] [Related]  

  • 29. p75 neurotrophin receptor interacts with and promotes BACE1 localization in endosomes aggravating amyloidogenesis.
    Saadipour K; Mañucat-Tan NB; Lim Y; Keating DJ; Smith KS; Zhong JH; Liao H; Bobrovskaya L; Wang YJ; Chao MV; Zhou XF
    J Neurochem; 2018 Feb; 144(3):302-317. PubMed ID: 28869759
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Amyloid precursor protein traffics from the Golgi directly to early endosomes in an Arl5b- and AP4-dependent pathway.
    Toh WH; Tan JZ; Zulkefli KL; Houghton FJ; Gleeson PA
    Traffic; 2017 Mar; 18(3):159-175. PubMed ID: 28000370
    [TBL] [Abstract][Full Text] [Related]  

  • 31. GGA1 regulates signal-dependent sorting of BACE1 to recycling endosomes, which moderates Aβ production.
    Toh WH; Chia PZC; Hossain MI; Gleeson PA
    Mol Biol Cell; 2018 Jan; 29(2):191-208. PubMed ID: 29142073
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Segregation of the membrane cargoes, BACE1 and amyloid precursor protein (APP) throughout the Golgi apparatus.
    Fourriere L; Cho EH; Gleeson PA
    Traffic; 2022 Mar; 23(3):158-173. PubMed ID: 35076977
    [TBL] [Abstract][Full Text] [Related]  

  • 33. BACE1 in Alzheimer's disease.
    Sathya M; Premkumar P; Karthick C; Moorthi P; Jayachandran KS; Anusuyadevi M
    Clin Chim Acta; 2012 Dec; 414():171-8. PubMed ID: 22926063
    [TBL] [Abstract][Full Text] [Related]  

  • 34. LDLR-related protein 10 (LRP10) regulates amyloid precursor protein (APP) trafficking and processing: evidence for a role in Alzheimer's disease.
    Brodeur J; Thériault C; Lessard-Beaudoin M; Marcil A; Dahan S; Lavoie C
    Mol Neurodegener; 2012 Jun; 7():31. PubMed ID: 22734645
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mechanisms of disease: new therapeutic strategies for Alzheimer's disease--targeting APP processing in lipid rafts.
    Cheng H; Vetrivel KS; Gong P; Meckler X; Parent A; Thinakaran G
    Nat Clin Pract Neurol; 2007 Jul; 3(7):374-82. PubMed ID: 17611486
    [TBL] [Abstract][Full Text] [Related]  

  • 36. BACE1 retrograde trafficking is uniquely regulated by the cytoplasmic domain of sortilin.
    Finan GM; Okada H; Kim TW
    J Biol Chem; 2011 Apr; 286(14):12602-16. PubMed ID: 21245145
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1.
    Sun M; Zhang H
    Neurobiol Aging; 2017 Dec; 60():129-140. PubMed ID: 28946017
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Swedish mutant APP-based BACE1 binding site peptide reduces APP β-cleavage and cerebral Aβ levels in Alzheimer's mice.
    Li S; Hou H; Mori T; Sawmiller D; Smith A; Tian J; Wang Y; Giunta B; Sanberg PR; Zhang S; Tan J
    Sci Rep; 2015 Jun; 5():11322. PubMed ID: 26091071
    [TBL] [Abstract][Full Text] [Related]  

  • 39. An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease.
    Kizuka Y; Kitazume S; Fujinawa R; Saito T; Iwata N; Saido TC; Nakano M; Yamaguchi Y; Hashimoto Y; Staufenbiel M; Hatsuta H; Murayama S; Manya H; Endo T; Taniguchi N
    EMBO Mol Med; 2015 Feb; 7(2):175-89. PubMed ID: 25592972
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Low-density lipoprotein receptor-related protein promotes amyloid precursor protein trafficking to lipid rafts in the endocytic pathway.
    Yoon IS; Chen E; Busse T; Repetto E; Lakshmana MK; Koo EH; Kang DE
    FASEB J; 2007 Sep; 21(11):2742-52. PubMed ID: 17463224
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.