BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

259 related articles for article (PubMed ID: 27418099)

  • 1. The MNK-1/eIF4E pathway as a new therapeutic pathway to target inflammation and remodelling in asthma.
    Seidel P; Sun Q; Costa L; Lardinois D; Tamm M; Roth M
    Cell Signal; 2016 Oct; 28(10):1555-62. PubMed ID: 27418099
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway.
    Wen Q; Wang W; Luo J; Chu S; Chen L; Xu L; Zang H; Alnemah MM; Ma J; Fan S
    Oncotarget; 2016 May; 7(19):27787-801. PubMed ID: 27050281
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mnk mediates integrin α6β4-dependent eIF4E phosphorylation and translation of VEGF mRNA.
    Korneeva NL; Soung YH; Kim HI; Giordano A; Rhoads RE; Gram H; Chung J
    Mol Cancer Res; 2010 Dec; 8(12):1571-8. PubMed ID: 21047768
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Asthmatic airway smooth muscle CXCL10 production: mitogen-activated protein kinase JNK involvement.
    Alrashdan YA; Alkhouri H; Chen E; Lalor DJ; Poniris M; Henness S; Brightling CE; Burgess JK; Armour CL; Ammit AJ; Hughes JM
    Am J Physiol Lung Cell Mol Physiol; 2012 May; 302(10):L1118-27. PubMed ID: 22387292
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of Mitogen-activated Protein Kinase (MAPK)-interacting Kinase (MNK) Preferentially Affects Translation of mRNAs Containing Both a 5'-Terminal Cap and Hairpin.
    Korneeva NL; Song A; Gram H; Edens MA; Rhoads RE
    J Biol Chem; 2016 Feb; 291(7):3455-67. PubMed ID: 26668315
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pro-inflammatory cytokine release in keratinocytes is mediated through the MAPK signal-integrating kinases.
    Kjellerup RB; Kragballe K; Iversen L; Johansen C
    Exp Dermatol; 2008 Jun; 17(6):498-504. PubMed ID: 18081851
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MNK1 inhibitor CGP57380 overcomes mTOR inhibitor-induced activation of eIF4E: the mechanism of synergic killing of human T-ALL cells.
    Huang XB; Yang CM; Han QM; Ye XJ; Lei W; Qian WB
    Acta Pharmacol Sin; 2018 Dec; 39(12):1894-1901. PubMed ID: 30297804
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of eukaryotic initiation factor 4E phosphorylation by cercosporamide selectively suppresses angiogenesis, growth and survival of human hepatocellular carcinoma.
    Liu Y; Sun L; Su X; Guo S
    Biomed Pharmacother; 2016 Dec; 84():237-243. PubMed ID: 27662474
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dimethylfumarate inhibits NF-{kappa}B function at multiple levels to limit airway smooth muscle cell cytokine secretion.
    Seidel P; Merfort I; Hughes JM; Oliver BG; Tamm M; Roth M
    Am J Physiol Lung Cell Mol Physiol; 2009 Aug; 297(2):L326-39. PubMed ID: 19465513
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of MNK pathways enhances cancer cell response to chemotherapy with temozolomide and targeted radionuclide therapy.
    Grzmil M; Seebacher J; Hess D; Behe M; Schibli R; Moncayo G; Frank S; Hemmings BA
    Cell Signal; 2016 Sep; 28(9):1412-1421. PubMed ID: 27289018
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting of the MNK-eIF4E axis in blast crisis chronic myeloid leukemia inhibits leukemia stem cell function.
    Lim S; Saw TY; Zhang M; Janes MR; Nacro K; Hill J; Lim AQ; Chang CT; Fruman DA; Rizzieri DA; Tan SY; Fan H; Chuah CT; Ong ST
    Proc Natl Acad Sci U S A; 2013 Jun; 110(25):E2298-307. PubMed ID: 23737503
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein phosphatase 2A negatively regulates eukaryotic initiation factor 4E phosphorylation and eIF4F assembly through direct dephosphorylation of Mnk and eIF4E.
    Li Y; Yue P; Deng X; Ueda T; Fukunaga R; Khuri FR; Sun SY
    Neoplasia; 2010 Oct; 12(10):848-55. PubMed ID: 20927323
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation.
    Wang X; Yue P; Chan CB; Ye K; Ueda T; Watanabe-Fukunaga R; Fukunaga R; Fu H; Khuri FR; Sun SY
    Mol Cell Biol; 2007 Nov; 27(21):7405-13. PubMed ID: 17724079
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells.
    Marzec M; Liu X; Wysocka M; Rook AH; Odum N; Wasik MA
    PLoS One; 2011; 6(9):e24849. PubMed ID: 21949767
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases.
    Konicek BW; Stephens JR; McNulty AM; Robichaud N; Peery RB; Dumstorf CA; Dowless MS; Iversen PW; Parsons S; Ellis KE; McCann DJ; Pelletier J; Furic L; Yingling JM; Stancato LF; Sonenberg N; Graff JR
    Cancer Res; 2011 Mar; 71(5):1849-57. PubMed ID: 21233335
    [TBL] [Abstract][Full Text] [Related]  

  • 16. First MNKs degrading agents block phosphorylation of eIF4E, induce apoptosis, inhibit cell growth, migration and invasion in triple negative and Her2-overexpressing breast cancer cell lines.
    Ramalingam S; Gediya L; Kwegyir-Afful AK; Ramamurthy VP; Purushottamachar P; Mbatia H; Njar VC
    Oncotarget; 2014 Jan; 5(2):530-43. PubMed ID: 24504069
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of MNK proteins and eIF4E phosphorylation in breast cancer cell proliferation and survival.
    Wheater MJ; Johnson PW; Blaydes JP
    Cancer Biol Ther; 2010 Oct; 10(7):728-35. PubMed ID: 20686366
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The androgen receptor is a negative regulator of eIF4E phosphorylation at S209: implications for the use of mTOR inhibitors in advanced prostate cancer.
    D'Abronzo LS; Bose S; Crapuchettes ME; Beggs RE; Vinall RL; Tepper CG; Siddiqui S; Mudryj M; Melgoza FU; Durbin-Johnson BP; deVere White RW; Ghosh PM
    Oncogene; 2017 Nov; 36(46):6359-6373. PubMed ID: 28745319
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Shiga toxins activate translational regulation pathways in intestinal epithelial cells.
    Colpoys WE; Cochran BH; Carducci TM; Thorpe CM
    Cell Signal; 2005 Jul; 17(7):891-9. PubMed ID: 15763431
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TGFβ-induced PI 3 kinase-dependent Mnk-1 activation is necessary for Ser-209 phosphorylation of eIF4E and mesangial cell hypertrophy.
    Das F; Ghosh-Choudhury N; Bera A; Kasinath BS; Choudhury GG
    J Cell Physiol; 2013 Jul; 228(7):1617-26. PubMed ID: 23359369
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.