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2. mTORC2 and Metabolic Reprogramming in GBM: at the Interface of Genetics and Environment. Masui K; Cavenee WK; Mischel PS Brain Pathol; 2015 Nov; 25(6):755-9. PubMed ID: 26526943 [TBL] [Abstract][Full Text] [Related]
3. Phosphorylation of the Hippo Pathway Component AMOTL2 by the mTORC2 Kinase Promotes YAP Signaling, Resulting in Enhanced Glioblastoma Growth and Invasiveness. Artinian N; Cloninger C; Holmes B; Benavides-Serrato A; Bashir T; Gera J J Biol Chem; 2015 Aug; 290(32):19387-401. PubMed ID: 25998128 [TBL] [Abstract][Full Text] [Related]
4. mTORC2 in the center of cancer metabolic reprogramming. Masui K; Cavenee WK; Mischel PS Trends Endocrinol Metab; 2014 Jul; 25(7):364-73. PubMed ID: 24856037 [TBL] [Abstract][Full Text] [Related]
5. ATP-site binding inhibitor effectively targets mTORC1 and mTORC2 complexes in glioblastoma. Neil J; Shannon C; Mohan A; Laurent D; Murali R; Jhanwar-Uniyal M Int J Oncol; 2016 Mar; 48(3):1045-52. PubMed ID: 26719046 [TBL] [Abstract][Full Text] [Related]
6. Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance. Masui K; Tanaka K; Ikegami S; Villa GR; Yang H; Yong WH; Cloughesy TF; Yamagata K; Arai N; Cavenee WK; Mischel PS Proc Natl Acad Sci U S A; 2015 Jul; 112(30):9406-11. PubMed ID: 26170313 [TBL] [Abstract][Full Text] [Related]
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8. Distinct signaling mechanisms of mTORC1 and mTORC2 in glioblastoma multiforme: a tale of two complexes. Jhanwar-Uniyal M; Gillick JL; Neil J; Tobias M; Thwing ZE; Murali R Adv Biol Regul; 2015 Jan; 57():64-74. PubMed ID: 25442674 [TBL] [Abstract][Full Text] [Related]
9. mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT. Gu Y; Albuquerque CP; Braas D; Zhang W; Villa GR; Bi J; Ikegami S; Masui K; Gini B; Yang H; Gahman TC; Shiau AK; Cloughesy TF; Christofk HR; Zhou H; Guan KL; Mischel PS Mol Cell; 2017 Jul; 67(1):128-138.e7. PubMed ID: 28648777 [TBL] [Abstract][Full Text] [Related]
10. Significance of filamin A in mTORC2 function in glioblastoma. Chantaravisoot N; Wongkongkathep P; Loo JA; Mischel PS; Tamanoi F Mol Cancer; 2015 Jul; 14():127. PubMed ID: 26134617 [TBL] [Abstract][Full Text] [Related]
11. Disentangling the signaling pathways of mTOR complexes, mTORC1 and mTORC2, as a therapeutic target in glioblastoma. Jhanwar-Uniyal M; Dominguez JF; Mohan AL; Tobias ME; Gandhi CD Adv Biol Regul; 2022 Jan; 83():100854. PubMed ID: 34996736 [TBL] [Abstract][Full Text] [Related]
12. Oncogenic EGFR signaling activates an mTORC2-NF-κB pathway that promotes chemotherapy resistance. Tanaka K; Babic I; Nathanson D; Akhavan D; Guo D; Gini B; Dang J; Zhu S; Yang H; De Jesus J; Amzajerdi AN; Zhang Y; Dibble CC; Dan H; Rinkenbaugh A; Yong WH; Vinters HV; Gera JF; Cavenee WK; Cloughesy TF; Manning BD; Baldwin AS; Mischel PS Cancer Discov; 2011 Nov; 1(6):524-38. PubMed ID: 22145100 [TBL] [Abstract][Full Text] [Related]
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17. Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma. Benavides-Serrato A; Lee J; Holmes B; Landon KA; Bashir T; Jung ME; Lichtenstein A; Gera J PLoS One; 2017; 12(4):e0176599. PubMed ID: 28453552 [TBL] [Abstract][Full Text] [Related]
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