BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

298 related articles for article (PubMed ID: 27428424)

  • 1. Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers.
    Illendula A; Gilmour J; Grembecka J; Tirumala VSS; Boulton A; Kuntimaddi A; Schmidt C; Wang L; Pulikkan JA; Zong H; Parlak M; Kuscu C; Pickin A; Zhou Y; Gao Y; Mishra L; Adli M; Castilla LH; Rajewski RA; Janes KA; Guzman ML; Bonifer C; Bushweller JH
    EBioMedicine; 2016 Jun; 8():117-131. PubMed ID: 27428424
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure and Biophysics of CBFβ/RUNX and Its Translocation Products.
    Tahirov TH; Bushweller J
    Adv Exp Med Biol; 2017; 962():21-31. PubMed ID: 28299648
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A tool compound targeting the core binding factor Runt domain to disrupt binding to CBFβ in leukemic cells.
    Oo ZM; Illendula A; Grembecka J; Schmidt C; Zhou Y; Esain V; Kwan W; Frost I; North TE; Rajewski RA; Speck NA; Bushweller JH
    Leuk Lymphoma; 2018 Sep; 59(9):2188-2200. PubMed ID: 29249175
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HIV type 1 viral infectivity factor and the RUNX transcription factors interact with core binding factor β on genetically distinct surfaces.
    Hultquist JF; McDougle RM; Anderson BD; Harris RS
    AIDS Res Hum Retroviruses; 2012 Dec; 28(12):1543-51. PubMed ID: 22725134
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The evolutionary origin of the Runx/CBFbeta transcription factors--studies of the most basal metazoans.
    Sullivan JC; Sher D; Eisenstein M; Shigesada K; Reitzel AM; Marlow H; Levanon D; Groner Y; Finnerty JR; Gat U
    BMC Evol Biol; 2008 Aug; 8():228. PubMed ID: 18681949
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Charged Amino Acid-rich Leucine Zipper-1 (Crlz-1) as a Target of Wnt Signaling Pathway Controls Pre-B Cell Proliferation by Affecting Runx/CBFβ-targeted VpreB and λ5 Genes.
    Choi SY; Park SK; Yoo HW; Pi JH; Kang CJ
    J Biol Chem; 2016 Jul; 291(29):15008-19. PubMed ID: 27226553
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Core Binding Factor-β Knockdown Alters Ovarian Gene Expression and Function in the Mouse.
    Wilson K; Park J; Curry TE; Mishra B; Gossen J; Taniuchi I; Jo M
    Mol Endocrinol; 2016 Jul; 30(7):733-47. PubMed ID: 27176614
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A mutation in the S-switch region of the Runt domain alters the dynamics of an allosteric network responsible for CBFbeta regulation.
    Li Z; Lukasik SM; Liu Y; Grembecka J; Bielnicka I; Bushweller JH; Speck NA
    J Mol Biol; 2006 Dec; 364(5):1073-83. PubMed ID: 17059830
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crlz1 activates transcription by mobilizing cytoplasmic CBFbeta into the nucleus.
    Park SK; Lim JH; Kang CJ
    Biochim Biophys Acta; 2009; 1789(11-12):702-8. PubMed ID: 19735751
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Association of core-binding factor β with the malignant phenotype of prostate and ovarian cancer cells.
    Davis JN; Rogers D; Adams L; Yong T; Jung JS; Cheng B; Fennell K; Borazanci E; Moustafa YW; Sun A; Shi R; Glass J; Mathis JM; Williams BJ; Meyers S
    J Cell Physiol; 2010 Nov; 225(3):875-87. PubMed ID: 20607802
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The RUNX Transcriptional Coregulator, CBFβ, Suppresses Migration of ER
    Pegg HJ; Harrison H; Rogerson C; Shore P
    Mol Cancer Res; 2019 May; 17(5):1015-1023. PubMed ID: 30655324
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Knockdown of core binding factorβ alters sphingolipid metabolism.
    Greer AH; Yong T; Fennell K; Moustafa YW; Fowler M; Galiano F; Ng SW; Berkowitz RS; Cardelli J; Meyers S; Davis JN
    J Cell Physiol; 2013 Dec; 228(12):2350-64. PubMed ID: 23813439
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Proleukemic RUNX1 and CBFbeta mutations in the pathogenesis of acute leukemia.
    Engel ME; Hiebert SW
    Cancer Treat Res; 2010; 145():127-47. PubMed ID: 20306249
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Allosteric inhibition of the protein-protein interaction between the leukemia-associated proteins Runx1 and CBFbeta.
    Gorczynski MJ; Grembecka J; Zhou Y; Kong Y; Roudaia L; Douvas MG; Newman M; Bielnicka I; Baber G; Corpora T; Shi J; Sridharan M; Lilien R; Donald BR; Speck NA; Brown ML; Bushweller JH
    Chem Biol; 2007 Oct; 14(10):1186-97. PubMed ID: 17961830
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An ancient neurotrophin receptor code; a single Runx/Cbfβ complex determines somatosensory neuron fate specification in zebrafish.
    Gau P; Curtright A; Condon L; Raible DW; Dhaka A
    PLoS Genet; 2017 Jul; 13(7):e1006884. PubMed ID: 28708822
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Small molecule inhibition of the CBFβ/RUNX interaction decreases ovarian cancer growth and migration through alterations in genes related to epithelial-to-mesenchymal transition.
    Carlton AL; Illendula A; Gao Y; Llaneza DC; Boulton A; Shah A; Rajewski RA; Landen CN; Wotton D; Bushweller JH
    Gynecol Oncol; 2018 May; 149(2):350-360. PubMed ID: 29551565
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RUNX1 is required for oncogenic
    Choi A; Illendula A; Pulikkan JA; Roderick JE; Tesell J; Yu J; Hermance N; Zhu LJ; Castilla LH; Bushweller JH; Kelliher MA
    Blood; 2017 Oct; 130(15):1722-1733. PubMed ID: 28790107
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Runx1-Cbfβ facilitates early B lymphocyte development by regulating expression of Ebf1.
    Seo W; Ikawa T; Kawamoto H; Taniuchi I
    J Exp Med; 2012 Jul; 209(7):1255-62. PubMed ID: 22665574
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CBFbeta is a facultative Runx partner in the sea urchin embryo.
    Robertson AJ; Dickey-Sims C; Ransick A; Rupp DE; McCarthy JJ; Coffman JA
    BMC Biol; 2006 Feb; 4():4. PubMed ID: 16469111
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Runx transcriptional co-activator, CBFbeta, is essential for invasion of breast cancer cells.
    Mendoza-Villanueva D; Deng W; Lopez-Camacho C; Shore P
    Mol Cancer; 2010 Jun; 9():171. PubMed ID: 20591170
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.