These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Bromodomain and extraterminal (BET) protein inhibition suppresses human T cell leukemia virus 1 (HTLV-1) Tax protein-mediated tumorigenesis by inhibiting nuclear factor κB (NF-κB) signaling. Wu X; Qi J; Bradner JE; Xiao G; Chen LF J Biol Chem; 2013 Dec; 288(50):36094-105. PubMed ID: 24189064 [TBL] [Abstract][Full Text] [Related]
3. SF2523: Dual PI3K/BRD4 Inhibitor Blocks Tumor Immunosuppression and Promotes Adaptive Immune Responses in Cancer. Joshi S; Singh AR; Liu KX; Pham TV; Zulcic M; Skola D; Chun HB; Glass CK; Morales GA; Garlich JR; Durden DL Mol Cancer Ther; 2019 Jun; 18(6):1036-1044. PubMed ID: 31018997 [TBL] [Abstract][Full Text] [Related]
4. BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses. Belkina AC; Nikolajczyk BS; Denis GV J Immunol; 2013 Apr; 190(7):3670-8. PubMed ID: 23420887 [TBL] [Abstract][Full Text] [Related]
5. Therapeutic targeting of BET protein BRD4 delays murine lupus. Wei S; Sun Y; Sha H Int Immunopharmacol; 2015 Dec; 29(2):314-319. PubMed ID: 26590112 [TBL] [Abstract][Full Text] [Related]
6. Targeting BRD4 proteins suppresses the growth of NSCLC through downregulation of eIF4E expression. Gao Z; Yuan T; Zhou X; Ni P; Sun G; Li P; Cheng Z; Wang X Cancer Biol Ther; 2018 May; 19(5):407-415. PubMed ID: 29333921 [TBL] [Abstract][Full Text] [Related]
7. Bromodomain and extraterminal domain-containing protein inhibition attenuates acute inflammation after spinal cord injury. Rudman MD; Choi JS; Lee HE; Tan SK; Ayad NG; Lee JK Exp Neurol; 2018 Nov; 309():181-192. PubMed ID: 30134146 [TBL] [Abstract][Full Text] [Related]
8. Epigenetic blockade of neoplastic transformation by bromodomain and extra-terminal (BET) domain protein inhibitor JQ-1. Zhang C; Su ZY; Wang L; Shu L; Yang Y; Guo Y; Pung D; Bountra C; Kong AN Biochem Pharmacol; 2016 Oct; 117():35-45. PubMed ID: 27520485 [TBL] [Abstract][Full Text] [Related]
9. BET bromodomain proteins regulate transcriptional reprogramming in genetic dilated cardiomyopathy. Antolic A; Wakimoto H; Jiao Z; Gorham JM; DePalma SR; Lemieux ME; Conner DA; Lee DY; Qi J; Seidman JG; Bradner JE; Brown JD; Haldar SM; Seidman CE; Burke MA JCI Insight; 2020 Aug; 5(15):. PubMed ID: 32603312 [TBL] [Abstract][Full Text] [Related]
10. Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer. Yamamoto K; Tateishi K; Kudo Y; Hoshikawa M; Tanaka M; Nakatsuka T; Fujiwara H; Miyabayashi K; Takahashi R; Tanaka Y; Ijichi H; Nakai Y; Isayama H; Morishita Y; Aoki T; Sakamoto Y; Hasegawa K; Kokudo N; Fukayama M; Koike K Oncotarget; 2016 Sep; 7(38):61469-61484. PubMed ID: 27528027 [TBL] [Abstract][Full Text] [Related]
11. Brd4 is essential for IL-1β-induced inflammation in human airway epithelial cells. Khan YM; Kirkham P; Barnes PJ; Adcock IM PLoS One; 2014; 9(4):e95051. PubMed ID: 24759736 [TBL] [Abstract][Full Text] [Related]
12. Nanog requires BRD4 to maintain murine embryonic stem cell pluripotency and is suppressed by bromodomain inhibitor JQ1 together with Lefty1. Horne GA; Stewart HJ; Dickson J; Knapp S; Ramsahoye B; Chevassut T Stem Cells Dev; 2015 Apr; 24(7):879-91. PubMed ID: 25393219 [TBL] [Abstract][Full Text] [Related]
14. The Bromodomain Inhibitor JQ1 and the Histone Deacetylase Inhibitor Panobinostat Synergistically Reduce N-Myc Expression and Induce Anticancer Effects. Shahbazi J; Liu PY; Atmadibrata B; Bradner JE; Marshall GM; Lock RB; Liu T Clin Cancer Res; 2016 May; 22(10):2534-44. PubMed ID: 26733615 [TBL] [Abstract][Full Text] [Related]
15. BRD4 suppression alleviates cerebral ischemia-induced brain injury by blocking glial activation via the inhibition of inflammatory response and pyroptosis. Zhou Y; Gu Y; Liu J Biochem Biophys Res Commun; 2019 Nov; 519(3):481-488. PubMed ID: 31530390 [TBL] [Abstract][Full Text] [Related]
16. RNA sequencing reveals distinct mechanisms underlying BET inhibitor JQ1-mediated modulation of the LPS-induced activation of BV-2 microglial cells. Jung KH; Das A; Chai JC; Kim SH; Morya N; Park KS; Lee YS; Chai YG J Neuroinflammation; 2015 Feb; 12():36. PubMed ID: 25890327 [TBL] [Abstract][Full Text] [Related]
17. BET Bromodomain Blockade Mitigates Intimal Hyperplasia in Rat Carotid Arteries. Wang B; Zhang M; Takayama T; Shi X; Roenneburg DA; Kent KC; Guo LW EBioMedicine; 2015 Nov; 2(11):1650-61. PubMed ID: 26870791 [TBL] [Abstract][Full Text] [Related]
18. BRD4 is a novel therapeutic target for liver fibrosis. Ding N; Hah N; Yu RT; Sherman MH; Benner C; Leblanc M; He M; Liddle C; Downes M; Evans RM Proc Natl Acad Sci U S A; 2015 Dec; 112(51):15713-8. PubMed ID: 26644586 [TBL] [Abstract][Full Text] [Related]
19. Inhibition of the acetyl lysine-binding pocket of bromodomain and extraterminal domain proteins interferes with adipogenesis. Goupille O; Penglong T; Kadri Z; Granger-Locatelli M; Fucharoen S; Maouche-Chrétien L; Prost S; Leboulch P; Chrétien S Biochem Biophys Res Commun; 2016 Apr; 472(4):624-30. PubMed ID: 26972250 [TBL] [Abstract][Full Text] [Related]
20. Bromodomain-containing protein 4 contributes to renal fibrosis through the induction of epithelial-mesenchymal transition. Wang X; Zhou Y; Peng Y; Huang T; Xia F; Yang T; Duan Q; Zhang W Exp Cell Res; 2019 Oct; 383(2):111507. PubMed ID: 31356816 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]