734 related articles for article (PubMed ID: 27439389)
1. Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice.
Hadano S; Mitsui S; Pan L; Otomo A; Kubo M; Sato K; Ono S; Onodera W; Abe K; Chen X; Koike M; Uchiyama Y; Aoki M; Warabi E; Yamamoto M; Ishii T; Yanagawa T; Shang HF; Yoshii F
Hum Mol Genet; 2016 Aug; 25(15):3321-3340. PubMed ID: 27439389
[TBL] [Abstract][Full Text] [Related]
2. Loss of ALS2/Alsin exacerbates motor dysfunction in a SOD1-expressing mouse ALS model by disturbing endolysosomal trafficking.
Hadano S; Otomo A; Kunita R; Suzuki-Utsunomiya K; Akatsuka A; Koike M; Aoki M; Uchiyama Y; Itoyama Y; Ikeda JE
PLoS One; 2010 Mar; 5(3):e9805. PubMed ID: 20339559
[TBL] [Abstract][Full Text] [Related]
3. Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1
Mitsui S; Otomo A; Nozaki M; Ono S; Sato K; Shirakawa R; Adachi H; Aoki M; Sobue G; Shang HF; Hadano S
Mol Brain; 2018 May; 11(1):30. PubMed ID: 29843805
[TBL] [Abstract][Full Text] [Related]
4. SQSTM1, a protective factor of SOD1-linked motor neuron disease, regulates the accumulation and distribution of ubiquitinated protein aggregates in neuron.
Mitsui S; Otomo A; Sato K; Ishiyama M; Shimakura K; Okada-Yamaguchi C; Warabi E; Yanagawa T; Aoki M; Shang HF; Hadano S
Neurochem Int; 2022 Sep; 158():105364. PubMed ID: 35640762
[TBL] [Abstract][Full Text] [Related]
5. Deficiency in the ALS2 gene does not affect the motor neuron degeneration in SOD1(G93A) transgenic mice.
Lin X; Shim H; Cai H
Neurobiol Aging; 2007 Oct; 28(10):1628-30. PubMed ID: 16973244
[TBL] [Abstract][Full Text] [Related]
6. Absence of lipofuscin in motor neurons of SOD1-linked ALS mice.
Bandyopadhyay U; Nagy M; Fenton WA; Horwich AL
Proc Natl Acad Sci U S A; 2014 Jul; 111(30):11055-60. PubMed ID: 25024188
[TBL] [Abstract][Full Text] [Related]
7. Different human copper-zinc superoxide dismutase mutants, SOD1G93A and SOD1H46R, exert distinct harmful effects on gross phenotype in mice.
Pan L; Yoshii Y; Otomo A; Ogawa H; Iwasaki Y; Shang HF; Hadano S
PLoS One; 2012; 7(3):e33409. PubMed ID: 22438926
[TBL] [Abstract][Full Text] [Related]
8. A cysteine residue affects the conformational state and neuronal toxicity of mutant SOD1 in mice: relevance to the pathogenesis of ALS.
Nagano S; Takahashi Y; Yamamoto K; Masutani H; Fujiwara N; Urushitani M; Araki T
Hum Mol Genet; 2015 Jun; 24(12):3427-39. PubMed ID: 25762155
[TBL] [Abstract][Full Text] [Related]
9. Progressive spinal axonal degeneration and slowness in ALS2-deficient mice.
Yamanaka K; Miller TM; McAlonis-Downes M; Chun SJ; Cleveland DW
Ann Neurol; 2006 Jul; 60(1):95-104. PubMed ID: 16802286
[TBL] [Abstract][Full Text] [Related]
10. ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway.
Deng Z; Lim J; Wang Q; Purtell K; Wu S; Palomo GM; Tan H; Manfredi G; Zhao Y; Peng J; Hu B; Chen S; Yue Z
Autophagy; 2020 May; 16(5):917-931. PubMed ID: 31362587
[TBL] [Abstract][Full Text] [Related]
11. Distinct roles for motor neuron autophagy early and late in the SOD1
Rudnick ND; Griffey CJ; Guarnieri P; Gerbino V; Wang X; Piersaint JA; Tapia JC; Rich MM; Maniatis T
Proc Natl Acad Sci U S A; 2017 Sep; 114(39):E8294-E8303. PubMed ID: 28904095
[TBL] [Abstract][Full Text] [Related]
12. ALS pathogenesis: recent insights from genetics and mouse models.
Swarup V; Julien JP
Prog Neuropsychopharmacol Biol Psychiatry; 2011 Mar; 35(2):363-9. PubMed ID: 20728492
[TBL] [Abstract][Full Text] [Related]
13. Amyotrophic lateral sclerosis-related mutant superoxide dismutase 1 aggregates inhibit 14-3-3-mediated cell survival by sequestration into the JUNQ compartment.
Park JH; Jang HR; Lee IY; Oh HK; Choi EJ; Rhim H; Kang S
Hum Mol Genet; 2017 Sep; 26(18):3615-3629. PubMed ID: 28666328
[TBL] [Abstract][Full Text] [Related]
14. Endogenous macrophage migration inhibitory factor reduces the accumulation and toxicity of misfolded SOD1 in a mouse model of ALS.
Leyton-Jaimes MF; Benaim C; Abu-Hamad S; Kahn J; Guetta A; Bucala R; Israelson A
Proc Natl Acad Sci U S A; 2016 Sep; 113(36):10198-203. PubMed ID: 27551074
[TBL] [Abstract][Full Text] [Related]
15. Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
Zhang X; Li L; Chen S; Yang D; Wang Y; Zhang X; Wang Z; Le W
Autophagy; 2011 Apr; 7(4):412-25. PubMed ID: 21193837
[TBL] [Abstract][Full Text] [Related]
16. Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons.
Castillo K; Nassif M; Valenzuela V; Rojas F; Matus S; Mercado G; Court FA; van Zundert B; Hetz C
Autophagy; 2013 Sep; 9(9):1308-20. PubMed ID: 23851366
[TBL] [Abstract][Full Text] [Related]
17. The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).
Crippa V; Sau D; Rusmini P; Boncoraglio A; Onesto E; Bolzoni E; Galbiati M; Fontana E; Marino M; Carra S; Bendotti C; De Biasi S; Poletti A
Hum Mol Genet; 2010 Sep; 19(17):3440-56. PubMed ID: 20570967
[TBL] [Abstract][Full Text] [Related]
18. Co-deposition of SOD1, TDP-43 and p62 proteinopathies in ALS: evidence for multifaceted pathways underlying neurodegeneration.
Trist BG; Fifita JA; Hogan A; Grima N; Smith B; Troakes C; Vance C; Shaw C; Al-Sarraj S; Blair IP; Double KL
Acta Neuropathol Commun; 2022 Aug; 10(1):122. PubMed ID: 36008843
[TBL] [Abstract][Full Text] [Related]
19. Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations.
Jeon GS; Shim YM; Lee DY; Kim JS; Kang M; Ahn SH; Shin JY; Geum D; Hong YH; Sung JJ
Mol Neurobiol; 2019 Mar; 56(3):2007-2021. PubMed ID: 29982983
[TBL] [Abstract][Full Text] [Related]
20. p62 accumulates and enhances aggregate formation in model systems of familial amyotrophic lateral sclerosis.
Gal J; Ström AL; Kilty R; Zhang F; Zhu H
J Biol Chem; 2007 Apr; 282(15):11068-77. PubMed ID: 17296612
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]