BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

610 related articles for article (PubMed ID: 27445147)

  • 1. Selective Motor Neuron Resistance and Recovery in a New Inducible Mouse Model of TDP-43 Proteinopathy.
    Spiller KJ; Cheung CJ; Restrepo CR; Kwong LK; Stieber AM; Trojanowski JQ; Lee VM
    J Neurosci; 2016 Jul; 36(29):7707-17. PubMed ID: 27445147
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Slow motor neurons resist pathological TDP-43 and mediate motor recovery in the rNLS8 model of amyotrophic lateral sclerosis.
    Hur SK; Hunter M; Dominique MA; Farag M; Cotton-Samuel D; Khan T; Trojanowski JQ; Spiller KJ; Lee VM
    Acta Neuropathol Commun; 2022 May; 10(1):75. PubMed ID: 35568882
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43.
    Walker AK; Spiller KJ; Ge G; Zheng A; Xu Y; Zhou M; Tripathy K; Kwong LK; Trojanowski JQ; Lee VM
    Acta Neuropathol; 2015 Nov; 130(5):643-60. PubMed ID: 26197969
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reduction of matrix metalloproteinase 9 (MMP-9) protects motor neurons from TDP-43-triggered death in rNLS8 mice.
    Spiller KJ; Khan T; Dominique MA; Restrepo CR; Cotton-Samuel D; Levitan M; Jafar-Nejad P; Zhang B; Soriano A; Rigo F; Trojanowski JQ; Lee VM
    Neurobiol Dis; 2019 Apr; 124():133-140. PubMed ID: 30458231
    [TBL] [Abstract][Full Text] [Related]  

  • 5. GPNMB ameliorates mutant TDP-43-induced motor neuron cell death.
    Nagahara Y; Shimazawa M; Ohuchi K; Ito J; Takahashi H; Tsuruma K; Kakita A; Hara H
    J Neurosci Res; 2017 Aug; 95(8):1647-1665. PubMed ID: 27935101
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Motor neuron vulnerability and resistance in amyotrophic lateral sclerosis.
    Nijssen J; Comley LH; Hedlund E
    Acta Neuropathol; 2017 Jun; 133(6):863-885. PubMed ID: 28409282
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutant TDP-43 in motor neurons promotes the onset and progression of ALS in rats.
    Huang C; Tong J; Bi F; Zhou H; Xia XG
    J Clin Invest; 2012 Jan; 122(1):107-18. PubMed ID: 22156203
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS.
    Mitchell JC; Constable R; So E; Vance C; Scotter E; Glover L; Hortobagyi T; Arnold ES; Ling SC; McAlonis M; Da Cruz S; Polymenidou M; Tessarolo L; Cleveland DW; Shaw CE
    Acta Neuropathol Commun; 2015 Jun; 3():36. PubMed ID: 26108367
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Motor neuron translatome reveals deregulation of SYNGR4 and PLEKHB1 in mutant TDP-43 amyotrophic lateral sclerosis models.
    Marques RF; Engler JB; Küchler K; Jones RA; Lingner T; Salinas G; Gillingwater TH; Friese MA; Duncan KE
    Hum Mol Genet; 2020 Sep; 29(16):2647-2661. PubMed ID: 32686835
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy.
    Spiller KJ; Restrepo CR; Khan T; Dominique MA; Fang TC; Canter RG; Roberts CJ; Miller KR; Ransohoff RM; Trojanowski JQ; Lee VM
    Nat Neurosci; 2018 Mar; 21(3):329-340. PubMed ID: 29463850
    [TBL] [Abstract][Full Text] [Related]  

  • 11. miR-23a suppression accelerates functional decline in the rNLS8 mouse model of TDP-43 proteinopathy.
    Tsitkanou S; Della Gatta PA; Abbott G; Wallace MA; Lindsay A; Gerlinger-Romero F; Walker AK; Foletta VC; Russell AP
    Neurobiol Dis; 2022 Jan; 162():105559. PubMed ID: 34774794
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gamma motor neurons survive and exacerbate alpha motor neuron degeneration in ALS.
    Lalancette-Hebert M; Sharma A; Lyashchenko AK; Shneider NA
    Proc Natl Acad Sci U S A; 2016 Dec; 113(51):E8316-E8325. PubMed ID: 27930290
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selective Expression of Osteopontin in ALS-resistant Motor Neurons is a Critical Determinant of Late Phase Neurodegeneration Mediated by Matrix Metalloproteinase-9.
    Morisaki Y; Niikura M; Watanabe M; Onishi K; Tanabe S; Moriwaki Y; Okuda T; Ohara S; Murayama S; Takao M; Uchida S; Yamanaka K; Misawa H
    Sci Rep; 2016 Jun; 6():27354. PubMed ID: 27264390
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery.
    Hunter M; Spiller KJ; Dominique MA; Xu H; Hunter FW; Fang TC; Canter RG; Roberts CJ; Ransohoff RM; Trojanowski JQ; Lee VM
    Acta Neuropathol Commun; 2021 Aug; 9(1):140. PubMed ID: 34412701
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A robust TDP-43 knock-in mouse model of ALS.
    Huang SL; Wu LS; Lee M; Chang CW; Cheng WC; Fang YS; Chen YR; Cheng PL; Shen CJ
    Acta Neuropathol Commun; 2020 Jan; 8(1):3. PubMed ID: 31964415
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Modeling hallmark pathology using motor neurons derived from the family and sporadic amyotrophic lateral sclerosis patient-specific iPS cells.
    Sun X; Song J; Huang H; Chen H; Qian K
    Stem Cell Res Ther; 2018 Nov; 9(1):315. PubMed ID: 30442180
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sporadic amyotrophic lateral sclerosis: is SMN-Gemins protein complex of importance for the relative resistance of oculomotor nucleus motoneurons to degeneration?
    Sulejczak D; Chrapusta SJ; Dziewulska D; Rafałowska J
    Folia Neuropathol; 2018; 56(4):308-320. PubMed ID: 30786668
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy.
    Chen HJ; Topp SD; Hui HS; Zacco E; Katarya M; McLoughlin C; King A; Smith BN; Troakes C; Pastore A; Shaw CE
    Brain; 2019 Dec; 142(12):3753-3770. PubMed ID: 31605140
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Overexpression of TDP-43 Protein in the Neuron and Oligodendrocyte Cells Causes the Progressive Motor Neuron Degeneration in the SOD1 G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.
    Lu Y; Tang C; Zhu L; Li J; Liang H; Zhang J; Xu R
    Int J Biol Sci; 2016; 12(9):1140-9. PubMed ID: 27570488
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration.
    Kaplan A; Spiller KJ; Towne C; Kanning KC; Choe GT; Geber A; Akay T; Aebischer P; Henderson CE
    Neuron; 2014 Jan; 81(2):333-48. PubMed ID: 24462097
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.