168 related articles for article (PubMed ID: 27447614)
1. Exploring the Molecular Basis for Binding of Inhibitors by Threonyl-tRNA Synthetase from Brucella abortus: A Virtual Screening Study.
Li M; Wen F; Zhao S; Wang P; Li S; Zhang Y; Zheng N; Wang J
Int J Mol Sci; 2016 Jul; 17(7):. PubMed ID: 27447614
[TBL] [Abstract][Full Text] [Related]
2. Structure-guided optimization and mechanistic study of a class of quinazolinone-threonine hybrids as antibacterial ThrRS inhibitors.
Guo J; Chen B; Yu Y; Cheng B; Ju Y; Tang J; Cai Z; Gu Q; Xu J; Zhou H
Eur J Med Chem; 2020 Dec; 207():112848. PubMed ID: 32980741
[TBL] [Abstract][Full Text] [Related]
3. Identification of borrelidin binding site on threonyl-tRNA synthetase.
Li M; Zhang J; Liu C; Fang B; Wang X; Xiang W
Biochem Biophys Res Commun; 2014 Sep; 451(4):485-90. PubMed ID: 25128830
[TBL] [Abstract][Full Text] [Related]
4. Discovery of novel tRNA-amino acid dual-site inhibitors against threonyl-tRNA synthetase by fragment-based target hopping.
Guo J; Chen B; Yu Y; Cheng B; Cheng Y; Ju Y; Gu Q; Xu J; Zhou H
Eur J Med Chem; 2020 Feb; 187():111941. PubMed ID: 31821989
[TBL] [Abstract][Full Text] [Related]
5. Conformational movements and cooperativity upon amino acid, ATP and tRNA binding in threonyl-tRNA synthetase.
Torres-Larios A; Sankaranarayanan R; Rees B; Dock-Bregeon AC; Moras D
J Mol Biol; 2003 Aug; 331(1):201-11. PubMed ID: 12875846
[TBL] [Abstract][Full Text] [Related]
6. Molecular and immunological characterisation of recombinant Brucella abortus glyceraldehyde-3-phosphate-dehydrogenase, a T- and B-cell reactive protein that induces partial protection when co-administered with an interleukin-12-expressing plasmid in a DNA vaccine formulation.
Rosinha GMS; Myioshi A; Azevedo V; Splitter GA; Oliveira SC
J Med Microbiol; 2002 Aug; 51(8):661-671. PubMed ID: 12171297
[TBL] [Abstract][Full Text] [Related]
7. A unique hydrophobic cluster near the active site contributes to differences in borrelidin inhibition among threonyl-tRNA synthetases.
Ruan B; Bovee ML; Sacher M; Stathopoulos C; Poralla K; Francklyn CS; Söll D
J Biol Chem; 2005 Jan; 280(1):571-7. PubMed ID: 15507440
[TBL] [Abstract][Full Text] [Related]
8. Threonyl-tRNA synthetase from Thermus thermophilus: purification and some structural and kinetic properties.
Zheltonosova J; Melnikova E; Garber M; Reinbolt J; Kern D; Ehresmann C; Ehresmann B
Biochimie; 1994; 76(1):71-7. PubMed ID: 8031907
[TBL] [Abstract][Full Text] [Related]
9. Molecular dynamics investigation into substrate binding and identity of the catalytic base in the mechanism of Threonyl-tRNA synthetase.
Bushnell EA; Huang W; Llano J; Gauld JW
J Phys Chem B; 2012 May; 116(17):5205-12. PubMed ID: 22482363
[TBL] [Abstract][Full Text] [Related]
10. Classical molecular dynamics simulation of seryl tRNA synthetase and threonyl tRNA synthetase bound with tRNA and aminoacyl adenylate.
Dutta S; Nandi N
J Biomol Struct Dyn; 2019 Feb; 37(2):336-358. PubMed ID: 29320932
[TBL] [Abstract][Full Text] [Related]
11. Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design.
Teng M; Hilgers MT; Cunningham ML; Borchardt A; Locke JB; Abraham S; Haley G; Kwan BP; Hall C; Hough GW; Shaw KJ; Finn J
J Med Chem; 2013 Feb; 56(4):1748-60. PubMed ID: 23362938
[TBL] [Abstract][Full Text] [Related]
12. Newly acquired N-terminal extension targets threonyl-tRNA synthetase-like protein into the multiple tRNA synthetase complex.
Zhou XL; Chen Y; Zeng QY; Ruan ZR; Fang P; Wang ED
Nucleic Acids Res; 2019 Sep; 47(16):8662-8674. PubMed ID: 31287872
[TBL] [Abstract][Full Text] [Related]
13. Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase.
Fang P; Yu X; Jeong SJ; Mirando A; Chen K; Chen X; Kim S; Francklyn CS; Guo M
Nat Commun; 2015 Mar; 6():6402. PubMed ID: 25824639
[TBL] [Abstract][Full Text] [Related]
14. Molecular mimicry in translational control of E. coli threonyl-tRNA synthetase gene. Competitive inhibition in tRNA aminoacylation and operator-repressor recognition switch using tRNA identity rules.
Romby P; Brunel C; Caillet J; Springer M; Grunberg-Manago M; Westhof E; Ehresmann C; Ehresmann B
Nucleic Acids Res; 1992 Nov; 20(21):5633-40. PubMed ID: 1280807
[TBL] [Abstract][Full Text] [Related]
15. The Brucella abortus Lon functions as a generalized stress response protease and is required for wild-type virulence in BALB/c mice.
Robertson GT; Kovach ME; Allen CA; Ficht TA; Roop RM
Mol Microbiol; 2000 Feb; 35(3):577-88. PubMed ID: 10672180
[TBL] [Abstract][Full Text] [Related]
16. Threonyl-tRNA synthetase from yeast. Discrimination of 19 amino acids in aminoacylation of tRNA(Thr)-C-C-A and tRNA(Thr)-C-C-A(2'NH2).
Freist W; Sternbach H; Cramer F
Eur J Biochem; 1994 Mar; 220(3):745-52. PubMed ID: 8143729
[TBL] [Abstract][Full Text] [Related]
17. Brucella abortus in captive bison. I. Serology, bacteriology, pathogenesis, and transmission to cattle.
Davis DS; Templeton JW; Ficht TA; Williams JD; Kopec JD; Adams LG
J Wildl Dis; 1990 Jul; 26(3):360-71. PubMed ID: 2117675
[TBL] [Abstract][Full Text] [Related]
18. Threonyl-tRNA synthetase of archaea: importance of the discriminator base in the aminoacylation of threonine tRNA.
Ishikura H; Nagaoka Y; Yokozawa J; Umehara T; Kuno A; Hasegawa T
Nucleic Acids Symp Ser; 2000; (44):83-4. PubMed ID: 12903279
[TBL] [Abstract][Full Text] [Related]
19. Affinity labeling of Escherichia coli histidyl-tRNA synthetase with reactive ATP analogues. Identification of labeled amino acid residues by matrix assisted laser desorption-ionization mass spectrometry.
Gillet S; Hoang CB; Schmitter JM; Fukui T; Blanquet S; Hountondji C
Eur J Biochem; 1996 Oct; 241(1):133-41. PubMed ID: 8898898
[TBL] [Abstract][Full Text] [Related]
20. Translational regulation of the Escherichia coli threonyl-tRNA synthetase gene: structural and functional importance of the thrS operator domains.
Brunel C; Romby P; Moine H; Caillet J; Grunberg-Manago M; Springer M; Ehresmann B; Ehresmann C
Biochimie; 1993; 75(12):1167-79. PubMed ID: 8199252
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]