436 related articles for article (PubMed ID: 27449046)
1. A novel colchicine-based microtubule inhibitor exhibits potent antitumor activity by inducing mitochondrial mediated apoptosis in MIA PaCa-2 pancreatic cancer cells.
Kumar A; Singh B; Mahajan G; Sharma PR; Bharate SB; Mintoo MJ; Mondhe DM
Tumour Biol; 2016 Oct; 37(10):13121-13136. PubMed ID: 27449046
[TBL] [Abstract][Full Text] [Related]
2. A novel microtubule depolymerizing colchicine analogue triggers apoptosis and autophagy in HCT-116 colon cancer cells.
Kumar A; Singh B; Sharma PR; Bharate SB; Saxena AK; Mondhe DM
Cell Biochem Funct; 2016 Mar; 34(2):69-81. PubMed ID: 26919061
[TBL] [Abstract][Full Text] [Related]
3. Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity.
Guzmán EA; Xu Q; Pitts TP; Mitsuhashi KO; Baker C; Linley PA; Oestreicher J; Tendyke K; Winder PL; Suh EM; Wright AE
Int J Cancer; 2016 Nov; 139(9):2116-26. PubMed ID: 27376928
[TBL] [Abstract][Full Text] [Related]
4. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
Yan J; Pang Y; Sheng J; Wang Y; Chen J; Hu J; Huang L; Li X
Biochem Pharmacol; 2015 Sep; 97(1):51-61. PubMed ID: 26212540
[TBL] [Abstract][Full Text] [Related]
5. Colchicine derivatives with potent anticancer activity and reduced P-glycoprotein induction liability.
Singh B; Kumar A; Joshi P; Guru SK; Kumar S; Wani ZA; Mahajan G; Hussain A; Qazi AK; Kumar A; Bharate SS; Gupta BD; Sharma PR; Hamid A; Saxena AK; Mondhe DM; Bhushan S; Bharate SB; Vishwakarma RA
Org Biomol Chem; 2015 May; 13(20):5674-89. PubMed ID: 25895604
[TBL] [Abstract][Full Text] [Related]
6. SKLB316, a novel small-molecule inhibitor of cell-cycle progression, induces G2/M phase arrest and apoptosis in vitro and inhibits tumor growth in vivo.
Xia Y; Lei Q; Zhu Y; Ye T; Wang N; Li G; Shi X; Liu Y; Shao B; Yin T; Zhao L; Wu W; Song X; Xiong Y; Wei Y; Yu L
Cancer Lett; 2014 Dec; 355(2):297-309. PubMed ID: 25301449
[TBL] [Abstract][Full Text] [Related]
7. Pyrrolotetrazinones deazaanalogues of temozolomide induce apoptosis in Jurkat cell line: involvement of tubulin polymerization inhibition.
Viola G; Cecconet L; Leszl A; Basso G; Brun P; Salvador A; Dall'Acqua F; Diana P; Barraja P; Cirrincione G
Cancer Chemother Pharmacol; 2009 Nov; 64(6):1235-51. PubMed ID: 19363609
[TBL] [Abstract][Full Text] [Related]
8. DAT-230, a novel microtubule inhibitor, exhibits potent anti-tumor activity by inducing G2/M phase arrest, apoptosis in vitro and perfusion decrease in vivo to HT-1080.
Qiao F; Zuo D; Shen X; Qi H; Wang H; Zhang W; Wu Y
Cancer Chemother Pharmacol; 2012 Aug; 70(2):259-70. PubMed ID: 22752214
[TBL] [Abstract][Full Text] [Related]
9. An oral quinoline derivative, MPT0B392, causes leukemic cells mitotic arrest and overcomes drug resistant cancer cells.
Chao MW; Huang HL; HuangFu WC; Hsu KC; Liu YM; Wu YW; Lin CF; Chen YL; Lai MJ; Lee HY; Liou JP; Teng CM; Yang CR
Oncotarget; 2017 Apr; 8(17):27772-27785. PubMed ID: 28186963
[TBL] [Abstract][Full Text] [Related]
10. BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.
Kuo CC; Hsieh HP; Pan WY; Chen CP; Liou JP; Lee SJ; Chang YL; Chen LT; Chen CT; Chang JY
Cancer Res; 2004 Jul; 64(13):4621-8. PubMed ID: 15231674
[TBL] [Abstract][Full Text] [Related]
11. YSL-12, a novel microtubule-destabilizing agent, exerts potent anti-tumor activity against colon cancer in vitro and in vivo.
Cai D; Qiu Z; Yao W; Liu Y; Huang H; Liao S; Luo Q; Xie L; Lin Z
Cancer Chemother Pharmacol; 2016 Jun; 77(6):1217-29. PubMed ID: 27107592
[TBL] [Abstract][Full Text] [Related]
12. A novel bis-indole destabilizes microtubules and displays potent in vitro and in vivo antitumor activity in prostate cancer.
Ahn S; Hwang DJ; Barrett CM; Yang J; Duke CB; Miller DD; Dalton JT
Cancer Chemother Pharmacol; 2011 Feb; 67(2):293-304. PubMed ID: 20383708
[TBL] [Abstract][Full Text] [Related]
13. In vitro and in vivo anticancer potential and molecular targets of the new colchicine analog IIIM-067.
Malik S; Mintoo MJ; Reddy CN; Kumar R; Kotwal P; Bharate SB; Nandi U; Mondhe DM; Shukla SK
J Integr Med; 2023 Jan; 21(1):62-76. PubMed ID: 36253285
[TBL] [Abstract][Full Text] [Related]
14. Novel analogue of colchicine induces selective pro-death autophagy and necrosis in human cancer cells.
Larocque K; Ovadje P; Djurdjevic S; Mehdi M; Green J; Pandey S
PLoS One; 2014; 9(1):e87064. PubMed ID: 24466327
[TBL] [Abstract][Full Text] [Related]
15. Apoptotic activity and antitumor efficacy of PEGylated TNF-related apoptosis-inducing ligand (TRAIL) in a Mia Paca-2 cell-xenografted mouse model.
Byeon HJ; Choi SH; Choi JS; Kim TH; Lee ES; Lee KC; Youn YS
Biomed Pharmacother; 2014 Feb; 68(1):65-9. PubMed ID: 24268811
[TBL] [Abstract][Full Text] [Related]
16. Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo.
Vogler M; Walczak H; Stadel D; Haas TL; Genze F; Jovanovic M; Gschwend JE; Simmet T; Debatin KM; Fulda S
Cancer Res; 2008 Oct; 68(19):7956-65. PubMed ID: 18829553
[TBL] [Abstract][Full Text] [Related]
17. Colchicine induces autophagy and senescence in lung cancer cells at clinically admissible concentration: potential use of colchicine in combination with autophagy inhibitor in cancer therapy.
Bhattacharya S; Das A; Datta S; Ganguli A; Chakrabarti G
Tumour Biol; 2016 Aug; 37(8):10653-64. PubMed ID: 26867767
[TBL] [Abstract][Full Text] [Related]
18. Cladosporol A triggers apoptosis sensitivity by ROS-mediated autophagic flux in human breast cancer cells.
Koul M; Kumar A; Deshidi R; Sharma V; Singh RD; Singh J; Sharma PR; Shah BA; Jaglan S; Singh S
BMC Cell Biol; 2017 Jul; 18(1):26. PubMed ID: 28728544
[TBL] [Abstract][Full Text] [Related]
19. Miltirone exhibits antileukemic activity by ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction pathways.
Zhou L; Jiang L; Xu M; Liu Q; Gao N; Li P; Liu EH
Sci Rep; 2016 Feb; 6():20585. PubMed ID: 26848099
[TBL] [Abstract][Full Text] [Related]
20. Selective killing of gastric cancer cells by a small molecule targeting ROS-mediated ER stress activation.
Zou P; Xia Y; Chen T; Zhang J; Wang Z; Chen W; Chen M; Kanchana K; Yang S; Liang G
Mol Carcinog; 2016 Jun; 55(6):1073-86. PubMed ID: 26086416
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
