These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

417 related articles for article (PubMed ID: 27450229)

  • 1. Evaluating Immunogenicity Risk Due to Host Cell Protein Impurities in Antibody-Based Biotherapeutics.
    Jawa V; Joubert MK; Zhang Q; Deshpande M; Hapuarachchi S; Hall MP; Flynn GC
    AAPS J; 2016 Nov; 18(6):1439-1452. PubMed ID: 27450229
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification and characterization of co-purifying CHO host cell proteins in monoclonal antibody purification process.
    Liu X; Chen Y; Zhao Y; Liu-Compton V; Chen W; Payne G; Lazar AC
    J Pharm Biomed Anal; 2019 Sep; 174():500-508. PubMed ID: 31234041
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of a host cell protein impurity in therapeutic protein, P1.
    Ahluwalia D; Dhillon H; Slaney T; Song H; Boux H; Mehta S; Zhang L; Valdez A; Krishnamurthy G
    J Pharm Biomed Anal; 2017 Jul; 141():32-38. PubMed ID: 28419935
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Trace levels of the CHO host cell protease cathepsin D caused particle formation in a monoclonal antibody product.
    Bee JS; Tie L; Johnson D; Dimitrova MN; Jusino KC; Afdahl CD
    Biotechnol Prog; 2015; 31(5):1360-9. PubMed ID: 26259961
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SWATH-MS as a strategy for CHO host cell protein identification and quantification supporting the characterization of mAb purification platforms.
    Carvalho SB; Profit L; Krishnan S; Gomes RA; Alexandre BM; Clavier S; Hoffman M; Brower K; Gomes-Alves P
    J Biotechnol; 2024 Mar; 384():1-11. PubMed ID: 38340900
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Quantitative host cell protein analysis using two dimensional data independent LC-MS(E).
    Farrell A; Mittermayr S; Morrissey B; Mc Loughlin N; Navas Iglesias N; Marison IW; Bones J
    Anal Chem; 2015 Sep; 87(18):9186-93. PubMed ID: 26280711
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification and characterization of CHO host-cell proteins in monoclonal antibody bioprocessing.
    Oh YH; Mendola KM; Choe LH; Min L; Lavoie AR; Sripada SA; Williams TI; Lee KH; Yigzaw Y; Seay A; Bill J; Li X; Roush DJ; Cramer SM; Menegatti S; Lenhoff AM
    Biotechnol Bioeng; 2024 Jan; 121(1):291-305. PubMed ID: 37877536
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhanced Detection of Low-Abundance Host Cell Protein Impurities in High-Purity Monoclonal Antibodies Down to 1 ppm Using Ion Mobility Mass Spectrometry Coupled with Multidimensional Liquid Chromatography.
    Doneanu CE; Anderson M; Williams BJ; Lauber MA; Chakraborty A; Chen W
    Anal Chem; 2015 Oct; 87(20):10283-91. PubMed ID: 26266576
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Toward unbiased identification and comparative quantification of host cell protein impurities by automated iterative LC-MS/MS (HCP-AIMS) for therapeutic protein development.
    Huang Y; Molden R; Hu M; Qiu H; Li N
    J Pharm Biomed Anal; 2021 Jun; 200():114069. PubMed ID: 33901758
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Host cell protein impurities in chromatographic polishing steps for monoclonal antibody purification.
    Levy NE; Valente KN; Lee KH; Lenhoff AM
    Biotechnol Bioeng; 2016 Jun; 113(6):1260-72. PubMed ID: 26550778
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expression of difficult-to-remove host cell protein impurities during extended Chinese hamster ovary cell culture and their impact on continuous bioprocessing.
    Valente KN; Lenhoff AM; Lee KH
    Biotechnol Bioeng; 2015 Jun; 112(6):1232-42. PubMed ID: 25502542
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Analysis of Host Cell Proteins in Monoclonal Antibody Therapeutics Through Size Exclusion Chromatography.
    Zhao B; Abdubek P; Zhang S; Xiao H; Li N
    Pharm Res; 2022 Nov; 39(11):3029-3037. PubMed ID: 36071355
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CHOPPI: a web tool for the analysis of immunogenicity risk from host cell proteins in CHO-based protein production.
    Bailey-Kellogg C; Gutiérrez AH; Moise L; Terry F; Martin WD; De Groot AS
    Biotechnol Bioeng; 2014 Nov; 111(11):2170-82. PubMed ID: 24888712
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Improved host cell protein analysis in monoclonal antibody products through ProteoMiner.
    Chen IH; Xiao H; Li N
    Anal Biochem; 2020 Dec; 610():113972. PubMed ID: 32979367
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ELISA reagent coverage evaluation by affinity purification tandem mass spectrometry.
    Henry SM; Sutlief E; Salas-Solano O; Valliere-Douglass J
    MAbs; 2017 Oct; 9(7):1065-1075. PubMed ID: 28708446
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A Novel Sample Preparation for Shotgun Proteomics Characterization of HCPs in Antibodies.
    Huang L; Wang N; Mitchell CE; Brownlee T; Maple SR; De Felippis MR
    Anal Chem; 2017 May; 89(10):5436-5444. PubMed ID: 28414239
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Improved Host Cell Protein Analysis in Monoclonal Antibody Products through Molecular Weight Cutoff Enrichment.
    Chen IH; Xiao H; Daly T; Li N
    Anal Chem; 2020 Mar; 92(5):3751-3757. PubMed ID: 31999105
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparison of platform host cell protein ELISA to process-specific host cell protein ELISA.
    Gunawan F; Nishihara J; Liu P; Sandoval W; Vanderlaan M; Zhang H; Krawitz D
    Biotechnol Bioeng; 2018 Feb; 115(2):382-389. PubMed ID: 28986978
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Factors affecting product association as a mechanism of host-cell protein persistence in bioprocessing.
    Oh YH; Becker ML; Mendola KM; Choe LH; Min L; Lee KH; Yigzaw Y; Seay A; Bill J; Li X; Roush DJ; Cramer SM; Menegatti S; Lenhoff AM
    Biotechnol Bioeng; 2024 Apr; 121(4):1284-1297. PubMed ID: 38240126
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mild hypothermic culture conditions affect residual host cell protein composition post-Protein A chromatography.
    Goey CH; Bell D; Kontoravdi C
    MAbs; 2018 Apr; 10(3):476-487. PubMed ID: 29381421
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.