238 related articles for article (PubMed ID: 27452521)
1. Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions.
Zámborszky J; Szikriszt B; Gervai JZ; Pipek O; Póti Á; Krzystanek M; Ribli D; Szalai-Gindl JM; Csabai I; Szallasi Z; Swanton C; Richardson AL; Szüts D
Oncogene; 2017 Feb; 36(6):746-755. PubMed ID: 27452521
[TBL] [Abstract][Full Text] [Related]
2. BRCA1 deficiency specific base substitution mutagenesis is dependent on translesion synthesis and regulated by 53BP1.
Chen D; Gervai JZ; Póti Á; Németh E; Szeltner Z; Szikriszt B; Gyüre Z; Zámborszky J; Ceccon M; d'Adda di Fagagna F; Szallasi Z; Richardson AL; Szüts D
Nat Commun; 2022 Jan; 13(1):226. PubMed ID: 35017534
[TBL] [Abstract][Full Text] [Related]
3. Error-prone repair of stalled replication forks drives mutagenesis and loss of heterozygosity in haploinsufficient BRCA1 cells.
Deshpande M; Paniza T; Jalloul N; Nanjangud G; Twarowski J; Koren A; Zaninovic N; Zhan Q; Chadalavada K; Malkova A; Khiabanian H; Madireddy A; Rosenwaks Z; Gerhardt J
Mol Cell; 2022 Oct; 82(20):3781-3793.e7. PubMed ID: 36099913
[TBL] [Abstract][Full Text] [Related]
4. Complex Characterization of Germline Large Genomic Rearrangements of the
Bozsik A; Pócza T; Papp J; Vaszkó T; Butz H; Patócs A; Oláh E
Int J Mol Sci; 2020 Jun; 21(13):. PubMed ID: 32629901
[TBL] [Abstract][Full Text] [Related]
5. Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents.
Póti Á; Gyergyák H; Németh E; Rusz O; Tóth S; Kovácsházi C; Chen D; Szikriszt B; Spisák S; Takeda S; Szakács G; Szallasi Z; Richardson AL; Szüts D
Genome Biol; 2019 Nov; 20(1):240. PubMed ID: 31727117
[TBL] [Abstract][Full Text] [Related]
6. A novel BRCA1 duplication and new insights on the spectrum and frequency of germline large genomic rearrangements in BRCA1/BRCA2.
Sahin I; Saat H
Mol Biol Rep; 2021 Jun; 48(6):5057-5062. PubMed ID: 34146199
[TBL] [Abstract][Full Text] [Related]
7. Screening for genomic rearrangements in BRCA1 and BRCA2 genes in Czech high-risk breast/ovarian cancer patients: high proportion of population specific alterations in BRCA1 gene.
Ticha I; Kleibl Z; Stribrna J; Kotlas J; Zimovjanova M; Mateju M; Zikan M; Pohlreich P
Breast Cancer Res Treat; 2010 Nov; 124(2):337-47. PubMed ID: 20135348
[TBL] [Abstract][Full Text] [Related]
8. Setting a diagnostic benchmark for tumor BRCA testing: detection of BRCA1 and BRCA2 large genomic rearrangements in FFPE tissue - A pilot study.
Valtcheva N; Nguyen-Sträuli BD; Wagner U; Freiberger SN; Varga Z; Britschgi C; Dedes KJ; Rechsteiner MP
Exp Mol Pathol; 2021 Dec; 123():104705. PubMed ID: 34637782
[TBL] [Abstract][Full Text] [Related]
9. Association of BRCA1- and BRCA2-deficiency with mutation burden, expression of PD-L1/PD-1, immune infiltrates, and T cell-inflamed signature in breast cancer.
Wen WX; Leong CO
PLoS One; 2019; 14(4):e0215381. PubMed ID: 31022191
[TBL] [Abstract][Full Text] [Related]
10. Large genomic rearrangements of BRCA1 and BRCA2 among patients referred for genetic analysis in Galicia (NW Spain): delimitation and mechanism of three novel BRCA1 rearrangements.
Fachal L; Blanco A; Santamariña M; Carracedo A; Vega A
PLoS One; 2014; 9(3):e93306. PubMed ID: 24686251
[TBL] [Abstract][Full Text] [Related]
11. Differing clinical impact of BRCA1 and BRCA2 mutations in serous ovarian cancer.
Liu G; Yang D; Sun Y; Shmulevich I; Xue F; Sood AK; Zhang W
Pharmacogenomics; 2012 Oct; 13(13):1523-35. PubMed ID: 23057551
[TBL] [Abstract][Full Text] [Related]
12. Therapeutic exploitation of tumor cell defects in homologous recombination.
Powell SN; Kachnic LA
Anticancer Agents Med Chem; 2008 May; 8(4):448-60. PubMed ID: 18473729
[TBL] [Abstract][Full Text] [Related]
13. Long-molecule scars of backup DNA repair in BRCA1- and BRCA2-deficient cancers.
Setton J; Hadi K; Choo ZN; Kuchin KS; Tian H; Da Cruz Paula A; Rosiene J; Selenica P; Behr J; Yao X; Deshpande A; Sigouros M; Manohar J; Nauseef JT; Mosquera JM; Elemento O; Weigelt B; Riaz N; Reis-Filho JS; Powell SN; Imieliński M
Nature; 2023 Sep; 621(7977):129-137. PubMed ID: 37587346
[TBL] [Abstract][Full Text] [Related]
14. Contribution of BRCA1 and BRCA2 mutations to inherited ovarian cancer.
Ramus SJ; Harrington PA; Pye C; DiCioccio RA; Cox MJ; Garlinghouse-Jones K; Oakley-Girvan I; Jacobs IJ; Hardy RM; Whittemore AS; Ponder BA; Piver MS; Pharoah PD; Gayther SA
Hum Mutat; 2007 Dec; 28(12):1207-15. PubMed ID: 17688236
[TBL] [Abstract][Full Text] [Related]
15. Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2.
Wang H; Zeng ZC; Bui TA; DiBiase SJ; Qin W; Xia F; Powell SN; Iliakis G
Cancer Res; 2001 Jan; 61(1):270-7. PubMed ID: 11196174
[TBL] [Abstract][Full Text] [Related]
16. Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains.
Park D; Shakya R; Koivisto C; Pitarresi JR; Szabolcs M; Kladney R; Hadjis A; Mace TA; Ludwig T
PLoS One; 2019; 14(12):e0226714. PubMed ID: 31877165
[TBL] [Abstract][Full Text] [Related]
17. Targeting the DNA repair defect of BRCA tumours.
Turner N; Tutt A; Ashworth A
Curr Opin Pharmacol; 2005 Aug; 5(4):388-93. PubMed ID: 15955736
[TBL] [Abstract][Full Text] [Related]
18. Anti-tumoural activity of the G-quadruplex ligand pyridostatin against BRCA1/2-deficient tumours.
Groelly FJ; Porru M; Zimmer J; Benainous H; De Visser Y; Kosova AA; Di Vito S; Serra V; Ryan A; Leonetti C; Bruna A; Biroccio A; Tarsounas M
EMBO Mol Med; 2022 Mar; 14(3):e14501. PubMed ID: 35107878
[TBL] [Abstract][Full Text] [Related]
19. Minding the gap: the underground functions of BRCA1 and BRCA2 at stalled replication forks.
Nagaraju G; Scully R
DNA Repair (Amst); 2007 Jul; 6(7):1018-31. PubMed ID: 17379580
[TBL] [Abstract][Full Text] [Related]
20. Comprehensive BRCA1 and BRCA2 mutational profile in Lithuania.
Janavičius R; Rudaitis V; Mickys U; Elsakov P; Griškevičius L
Cancer Genet; 2014 May; 207(5):195-205. PubMed ID: 25066507
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
