439 related articles for article (PubMed ID: 27452907)
1. Shikonin induces apoptosis of lung cancer cells via activation of FOXO3a/EGR1/SIRT1 signaling antagonized by p300.
Jeung YJ; Kim HG; Ahn J; Lee HJ; Lee SB; Won M; Jung CR; Im JY; Kim BK; Park SK; Son MJ; Chung KS
Biochim Biophys Acta; 2016 Nov; 1863(11):2584-2593. PubMed ID: 27452907
[TBL] [Abstract][Full Text] [Related]
2. T63, a new 4-arylidene curcumin analogue, induces cell cycle arrest and apoptosis through activation of the reactive oxygen species-FOXO3a pathway in lung cancer cells.
Liu H; Zhou BH; Qiu X; Wang HS; Zhang F; Fang R; Wang XF; Cai SH; Du J; Bu XZ
Free Radic Biol Med; 2012 Dec; 53(12):2204-17. PubMed ID: 23085518
[TBL] [Abstract][Full Text] [Related]
3. FOXO3a reactivation mediates the synergistic cytotoxic effects of rapamycin and cisplatin in oral squamous cell carcinoma cells.
Fang L; Wang H; Zhou L; Yu D
Toxicol Appl Pharmacol; 2011 Feb; 251(1):8-15. PubMed ID: 21092744
[TBL] [Abstract][Full Text] [Related]
4. Reactive oxygen species-mediated activation of the Akt/ASK1/p38 signaling cascade and p21(Cip1) downregulation are required for shikonin-induced apoptosis.
Ahn J; Won M; Choi JH; Kim YS; Jung CR; Im DS; Kyun ML; Lee K; Song KB; Chung KS
Apoptosis; 2013 Jul; 18(7):870-81. PubMed ID: 23546866
[TBL] [Abstract][Full Text] [Related]
5. Akt-FOXO3a signaling axis dysregulation in human oral squamous cell carcinoma and potent efficacy of FOXO3a-targeted gene therapy.
Fang L; Wang H; Zhou L; Yu D
Oral Oncol; 2011 Jan; 47(1):16-21. PubMed ID: 21109483
[TBL] [Abstract][Full Text] [Related]
6. 18β-glycyrrhetinic acid induces apoptosis through modulation of Akt/FOXO3a/Bim pathway in human breast cancer MCF-7 cells.
Sharma G; Kar S; Palit S; Das PK
J Cell Physiol; 2012 May; 227(5):1923-31. PubMed ID: 21732363
[TBL] [Abstract][Full Text] [Related]
7. EGFR-TKI resistance due to BIM polymorphism can be circumvented in combination with HDAC inhibition.
Nakagawa T; Takeuchi S; Yamada T; Ebi H; Sano T; Nanjo S; Ishikawa D; Sato M; Hasegawa Y; Sekido Y; Yano S
Cancer Res; 2013 Apr; 73(8):2428-34. PubMed ID: 23382048
[TBL] [Abstract][Full Text] [Related]
8. FOXO3a mediates the cytotoxic effects of cisplatin in lung cancer cells.
Liu H; Yin J; Wang C; Gu Y; Deng M; He Z
Anticancer Drugs; 2014 Sep; 25(8):898-907. PubMed ID: 24814195
[TBL] [Abstract][Full Text] [Related]
9. Shikonin induces cell cycle arrest in human gastric cancer (AGS) by early growth response 1 (Egr1)-mediated p21 gene expression.
Kim SJ; Kim JM; Shim SH; Chang HI
J Ethnopharmacol; 2014 Feb; 151(3):1064-1071. PubMed ID: 24384380
[TBL] [Abstract][Full Text] [Related]
10. Purified vitexin compound 1 induces apoptosis through activation of FOXO3a in hepatocellular carcinoma.
Wang JG; Zheng XX; Zeng GY; Zhou YJ; Yuan H
Oncol Rep; 2014 Jan; 31(1):488-96. PubMed ID: 24247909
[TBL] [Abstract][Full Text] [Related]
11. SIRT1 Protects Against Oxidative Stress-Induced Endothelial Progenitor Cells Apoptosis by Inhibiting FOXO3a via FOXO3a Ubiquitination and Degradation.
Wang YQ; Cao Q; Wang F; Huang LY; Sang TT; Liu F; Chen SY
J Cell Physiol; 2015 Sep; 230(9):2098-107. PubMed ID: 25640014
[TBL] [Abstract][Full Text] [Related]
12. DUSP1 expression induced by HDAC1 inhibition mediates gefitinib sensitivity in non-small cell lung cancers.
Lin YC; Lin YC; Shih JY; Huang WJ; Chao SW; Chang YL; Chen CC
Clin Cancer Res; 2015 Jan; 21(2):428-38. PubMed ID: 25593344
[TBL] [Abstract][Full Text] [Related]
13. Apoptosis induction by MEK inhibition in human lung cancer cells is mediated by Bim.
Meng J; Fang B; Liao Y; Chresta CM; Smith PD; Roth JA
PLoS One; 2010 Sep; 5(9):e13026. PubMed ID: 20885957
[TBL] [Abstract][Full Text] [Related]
14. Cbl participates in shikonin-induced apoptosis by negatively regulating phosphoinositide 3-kinase/protein kinase B signaling.
Qu D; Xu XM; Zhang M; Jiang TS; Zhang Y; Li SQ
Mol Med Rep; 2015 Jul; 12(1):1305-13. PubMed ID: 25815461
[TBL] [Abstract][Full Text] [Related]
15. TG-interacting factor transcriptionally induced by AKT/FOXO3A is a negative regulator that antagonizes arsenic trioxide-induced cancer cell apoptosis.
Liu ZM; Tseng HY; Cheng YL; Yeh BW; Wu WJ; Huang HS
Toxicol Appl Pharmacol; 2015 May; 285(1):41-50. PubMed ID: 25791921
[TBL] [Abstract][Full Text] [Related]
16. Knockdown of CABYR-a/b increases chemosensitivity of human non-small cell lung cancer cells through inactivation of Akt.
Qian Z; Li M; Wang R; Xiao Q; Wang J; Li M; He D; Xiao X
Mol Cancer Res; 2014 Mar; 12(3):335-47. PubMed ID: 24362251
[TBL] [Abstract][Full Text] [Related]
17. A novel histone deacetylase inhibitor exhibits antitumor activity via apoptosis induction, F-actin disruption and gene acetylation in lung cancer.
Tang YA; Wen WL; Chang JW; Wei TT; Tan YH; Salunke S; Chen CT; Chen CS; Wang YC
PLoS One; 2010 Sep; 5(9):e12417. PubMed ID: 20856855
[TBL] [Abstract][Full Text] [Related]
18. Pancreatic tumor suppression by benzyl isothiocyanate is associated with inhibition of PI3K/AKT/FOXO pathway.
Boreddy SR; Pramanik KC; Srivastava SK
Clin Cancer Res; 2011 Apr; 17(7):1784-95. PubMed ID: 21350002
[TBL] [Abstract][Full Text] [Related]
19. NSC126188 induces apoptosis of prostate cancer PC-3 cells through inhibition of Akt membrane translocation, FoxO3a activation, and RhoB transcription.
Won KJ; Kim BK; Han G; Lee K; Jung YJ; Kim HM; Song KB; Chung KS; Won M
Apoptosis; 2014 Jan; 19(1):179-90. PubMed ID: 24085402
[TBL] [Abstract][Full Text] [Related]
20. SIRT1 and AMPK mediate hypoxia-induced resistance of non-small cell lung cancers to cisplatin and doxorubicin.
Shin DH; Choi YJ; Park JW
Cancer Res; 2014 Jan; 74(1):298-308. PubMed ID: 24240701
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
