BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

110 related articles for article (PubMed ID: 27458663)

  • 1. Anticalins directed against vascular endothelial growth factor receptor 3 (VEGFR-3) with picomolar affinities show potential for medical therapy and in vivo imaging.
    Richter A; Skerra A
    Biol Chem; 2017 Jan; 398(1):39-55. PubMed ID: 27458663
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selection and characterization of Anticalins targeting human prostate-specific membrane antigen (PSMA).
    Barinka C; Ptacek J; Richter A; Novakova Z; Morath V; Skerra A
    Protein Eng Des Sel; 2016 Mar; 29(3):105-15. PubMed ID: 26802163
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation.
    Leppänen VM; Tvorogov D; Kisko K; Prota AE; Jeltsch M; Anisimov A; Markovic-Mueller S; Stuttfeld E; Goldie KN; Ballmer-Hofer K; Alitalo K
    Proc Natl Acad Sci U S A; 2013 Aug; 110(32):12960-5. PubMed ID: 23878260
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis.
    Heckman CA; Holopainen T; Wirzenius M; Keskitalo S; Jeltsch M; Ylä-Herttuala S; Wedge SR; Jürgensmeier JM; Alitalo K
    Cancer Res; 2008 Jun; 68(12):4754-62. PubMed ID: 18559522
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RNAi-mediated silencing of VEGF-C inhibits non-small cell lung cancer progression by simultaneously down-regulating the CXCR4, CCR7, VEGFR-2 and VEGFR-3-dependent axes-induced ERK, p38 and AKT signalling pathways.
    Feng Y; Hu J; Ma J; Feng K; Zhang X; Yang S; Wang W; Zhang J; Zhang Y
    Eur J Cancer; 2011 Oct; 47(15):2353-63. PubMed ID: 21680174
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Vascular endothelial growth factor (VEGF)/VEGF-C mosaic molecules reveal specificity determinants and feature novel receptor binding patterns.
    Jeltsch M; Karpanen T; Strandin T; Aho K; Lankinen H; Alitalo K
    J Biol Chem; 2006 Apr; 281(17):12187-95. PubMed ID: 16505489
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of high-affinity VEGFR3-binding peptides through a phage-displayed random peptide library.
    Shi LF; Wu Y; Li CY
    J Gynecol Oncol; 2015 Oct; 26(4):327-35. PubMed ID: 26197772
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural determinants of vascular endothelial growth factor-D receptor binding and specificity.
    Leppänen VM; Jeltsch M; Anisimov A; Tvorogov D; Aho K; Kalkkinen N; Toivanen P; Ylä-Herttuala S; Ballmer-Hofer K; Alitalo K
    Blood; 2011 Feb; 117(5):1507-15. PubMed ID: 21148085
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Anticalins small engineered binding proteins based on the lipocalin scaffold.
    Gebauer M; Skerra A
    Methods Enzymol; 2012; 503():157-88. PubMed ID: 22230569
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combinatorial design of an Anticalin directed against the extra-domain b for the specific targeting of oncofetal fibronectin.
    Gebauer M; Schiefner A; Matschiner G; Skerra A
    J Mol Biol; 2013 Feb; 425(4):780-802. PubMed ID: 23238252
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential expression of VEGF ligands and receptors in prostate cancer.
    Woollard DJ; Opeskin K; Coso S; Wu D; Baldwin ME; Williams ED
    Prostate; 2013 May; 73(6):563-72. PubMed ID: 23038639
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anticalins Reveal High Plasticity in the Mode of Complex Formation with a Common Tumor Antigen.
    Schiefner A; Gebauer M; Richter A; Skerra A
    Structure; 2018 Apr; 26(4):649-656.e3. PubMed ID: 29526433
    [TBL] [Abstract][Full Text] [Related]  

  • 13. High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer β-amyloid peptide.
    Rauth S; Hinz D; Börger M; Uhrig M; Mayhaus M; Riemenschneider M; Skerra A
    Biochem J; 2016 Jun; 473(11):1563-78. PubMed ID: 27029347
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Vascular endothelial growth factor C stimulates progression of human gastric cancer via both autocrine and paracrine mechanisms.
    Kodama M; Kitadai Y; Tanaka M; Kuwai T; Tanaka S; Oue N; Yasui W; Chayama K
    Clin Cancer Res; 2008 Nov; 14(22):7205-14. PubMed ID: 19010837
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Foretinib inhibits angiogenesis, lymphangiogenesis and tumor growth of pancreatic cancer in vivo by decreasing VEGFR-2/3 and TIE-2 signaling.
    Chen HM; Tsai CH; Hung WC
    Oncotarget; 2015 Jun; 6(17):14940-52. PubMed ID: 25909285
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Suppression of lymphangiogenesis by soluble vascular endothelial growth factor receptor-2 in a mouse lung cancer model.
    Maehana S; Nakamura M; Ogawa F; Imai R; Murakami R; Kojima F; Majima M; Kitasato H
    Biomed Pharmacother; 2016 Dec; 84():660-665. PubMed ID: 27697638
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alternative binding proteins: anticalins - harnessing the structural plasticity of the lipocalin ligand pocket to engineer novel binding activities.
    Skerra A
    FEBS J; 2008 Jun; 275(11):2677-83. PubMed ID: 18435758
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization.
    Tvorogov D; Anisimov A; Zheng W; Leppänen VM; Tammela T; Laurinavicius S; Holnthoner W; Heloterä H; Holopainen T; Jeltsch M; Kalkkinen N; Lankinen H; Ojala PM; Alitalo K
    Cancer Cell; 2010 Dec; 18(6):630-40. PubMed ID: 21130043
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Vascular endothelial growth factor receptor 3 is involved in tumor angiogenesis and growth.
    Laakkonen P; Waltari M; Holopainen T; Takahashi T; Pytowski B; Steiner P; Hicklin D; Persaud K; Tonra JR; Witte L; Alitalo K
    Cancer Res; 2007 Jan; 67(2):593-9. PubMed ID: 17234768
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Expression and clinical significance of vascular endothelial growth factor C and vascular endothelial growth factor receptor 3 in non-small cell lung carcinoma].
    Lu ZQ; Li HG; Xie DR; Zhang HZ; Shen XM; Zeng YJ; Zeng H
    Ai Zheng; 2005 Sep; 24(9):1132-5. PubMed ID: 16159440
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.