These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 27464833)

  • 1. Cellular response to alkylating agent MNNG is impaired in STAT1-deficients cells.
    Ah-Koon L; Lesage D; Lemadre E; Souissi I; Fagard R; Varin-Blank N; Fabre EE; Schischmanoff O
    J Cell Mol Med; 2016 Oct; 20(10):1956-65. PubMed ID: 27464833
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MMR/c-Abl-dependent activation of ING2/p73alpha signaling regulates the cell death response to N-methyl-N'-nitro-N-nitrosoguanidine.
    Sun G; Jin S; Baskaran R
    Exp Cell Res; 2009 Nov; 315(18):3163-75. PubMed ID: 19766113
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of c-Abl kinase in DNA mismatch repair-dependent G2 cell cycle checkpoint arrest responses.
    Wagner MW; Li LS; Morales JC; Galindo CL; Garner HR; Bornmann WG; Boothman DA
    J Biol Chem; 2008 Aug; 283(31):21382-93. PubMed ID: 18480061
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The alkylating carcinogen N-methyl-N'-nitro-N-nitrosoguanidine activates the plasminogen activator inhibitor-1 gene through sequential phosphorylation of p53 by ATM and ATR kinases.
    Vidal B; Parra M; Jardí M; Saito S; Appella E; Muñoz-Cánoves P
    Thromb Haemost; 2005 Mar; 93(3):584-91. PubMed ID: 15735814
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ATM is activated in response to N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA alkylation.
    Adamson AW; Kim WJ; Shangary S; Baskaran R; Brown KD
    J Biol Chem; 2002 Oct; 277(41):38222-9. PubMed ID: 12151394
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The monofunctional alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine triggers apoptosis through p53-dependent and -independent pathways.
    Kim WJ; Beardsley DI; Adamson AW; Brown KD
    Toxicol Appl Pharmacol; 2005 Jan; 202(1):84-98. PubMed ID: 15589979
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint.
    Hawn MT; Umar A; Carethers JM; Marra G; Kunkel TA; Boland CR; Koi M
    Cancer Res; 1995 Sep; 55(17):3721-5. PubMed ID: 7641183
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2.
    Adamson AW; Beardsley DI; Kim WJ; Gao Y; Baskaran R; Brown KD
    Mol Biol Cell; 2005 Mar; 16(3):1513-26. PubMed ID: 15647386
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Non-apoptogenic killing of hela cervical carcinoma cells after short exposure to the alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
    Wesierska-Gadek J; Gueorguieva M; Schloffer D; Uhl M; Wojciechowski J
    J Cell Biochem; 2003 Aug; 89(6):1222-34. PubMed ID: 12898520
    [TBL] [Abstract][Full Text] [Related]  

  • 10. N-methyl-N'-nitro-N-nitrosoguanidine-induced senescence-like growth arrest in colon cancer cells is associated with loss of adenomatous polyposis coli protein, microtubule organization, and telomeric DNA.
    Jaiswal AS; Multani AS; Pathak S; Narayan S
    Mol Cancer; 2004 Jan; 3():3. PubMed ID: 14728717
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MLH1- and ATM-dependent MAPK signaling is activated through c-Abl in response to the alkylator N-methyl-N'-nitro-N'-nitrosoguanidine.
    Kim WJ; Rajasekaran B; Brown KD
    J Biol Chem; 2007 Nov; 282(44):32021-31. PubMed ID: 17804421
    [TBL] [Abstract][Full Text] [Related]  

  • 12. p53 Phosphorylation at serine 15 is required for transcriptional induction of the plasminogen activator inhibitor-1 (PAI-1) gene by the alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine.
    Parra M; Jardí M; Koziczak M; Nagamine Y; Muñoz-Cánoves P
    J Biol Chem; 2001 Sep; 276(39):36303-10. PubMed ID: 11470783
    [TBL] [Abstract][Full Text] [Related]  

  • 13. N-methyl-N'-nitro-N-nitrosoguanidine activates cell-cycle arrest through distinct mechanisms activated in a dose-dependent manner.
    Beardsley DI; Kim WJ; Brown KD
    Mol Pharmacol; 2005 Oct; 68(4):1049-60. PubMed ID: 15994368
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA mismatch repair-dependent activation of c-Abl/p73alpha/GADD45alpha-mediated apoptosis.
    Li LS; Morales JC; Hwang A; Wagner MW; Boothman DA
    J Biol Chem; 2008 Aug; 283(31):21394-403. PubMed ID: 18480060
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N'-nitro-N-nitrosoguanidine.
    Carethers JM; Hawn MT; Chauhan DP; Luce MC; Marra G; Koi M; Boland CR
    J Clin Invest; 1996 Jul; 98(1):199-206. PubMed ID: 8690794
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Histone H2AX is a critical factor for cellular protection against DNA alkylating agents.
    Meador JA; Zhao M; Su Y; Narayan G; Geard CR; Balajee AS
    Oncogene; 2008 Sep; 27(43):5662-71. PubMed ID: 18542054
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Exonuclease 1 (Exo1) is required for activating response to S(N)1 DNA methylating agents.
    Izumchenko E; Saydi J; Brown KD
    DNA Repair (Amst); 2012 Dec; 11(12):951-64. PubMed ID: 23062884
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of a novel p53-dependent activation pathway of STAT1 by antitumour genotoxic agents.
    Youlyouz-Marfak I; Gachard N; Le Clorennec C; Najjar I; Baran-Marszak F; Reminieras L; May E; Bornkamm GW; Fagard R; Feuillard J
    Cell Death Differ; 2008 Feb; 15(2):376-85. PubMed ID: 17992189
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The bacterial alkyltransferase-like (eATL) protein protects mammalian cells against methylating agent-induced toxicity.
    Tomaszowski KH; Aasland D; Margison GP; Williams E; Pinder SI; Modesti M; Fuchs RP; Kaina B
    DNA Repair (Amst); 2015 Apr; 28():14-20. PubMed ID: 25703834
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protein tyrosine nitration and poly(ADP-ribose) polymerase activation in N-methyl-N-nitro-N-nitrosoguanidine-treated thymocytes: implication for cytotoxicity.
    Bai P; Hegedus C; Erdélyi K; Szabó E; Bakondi E; Gergely S; Szabó C; Virág L
    Toxicol Lett; 2007 May; 170(3):203-13. PubMed ID: 17428624
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.