136 related articles for article (PubMed ID: 27466182)
1. SHOC2 subcellular shuttling requires the KEKE motif-rich region and N-terminal leucine-rich repeat domain and impacts on ERK signalling.
Motta M; Chillemi G; Fodale V; Cecchetti S; Coppola S; Stipo S; Cordeddu V; Macioce P; Gelb BD; Tartaglia M
Hum Mol Genet; 2016 Sep; 25(17):3824-3835. PubMed ID: 27466182
[TBL] [Abstract][Full Text] [Related]
2. Clinical and functional characterization of a novel RASopathy-causing SHOC2 mutation associated with prenatal-onset hypertrophic cardiomyopathy.
Motta M; Giancotti A; Mastromoro G; Chandramouli B; Pinna V; Pantaleoni F; Di Giosaffatte N; Petrini S; Mazza T; D'Ambrosio V; Versacci P; Ventriglia F; Chillemi G; Pizzuti A; Tartaglia M; De Luca A
Hum Mutat; 2019 Aug; 40(8):1046-1056. PubMed ID: 31059601
[TBL] [Abstract][Full Text] [Related]
3. Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair.
Cordeddu V; Di Schiavi E; Pennacchio LA; Ma'ayan A; Sarkozy A; Fodale V; Cecchetti S; Cardinale A; Martin J; Schackwitz W; Lipzen A; Zampino G; Mazzanti L; Digilio MC; Martinelli S; Flex E; Lepri F; Bartholdi D; Kutsche K; Ferrero GB; Anichini C; Selicorni A; Rossi C; Tenconi R; Zenker M; Merlo D; Dallapiccola B; Iyengar R; Bazzicalupo P; Gelb BD; Tartaglia M
Nat Genet; 2009 Sep; 41(9):1022-6. PubMed ID: 19684605
[TBL] [Abstract][Full Text] [Related]
4. SHOC2-MRAS-PP1 complex positively regulates RAF activity and contributes to Noonan syndrome pathogenesis.
Young LC; Hartig N; Boned Del Río I; Sari S; Ringham-Terry B; Wainwright JR; Jones GG; McCormick F; Rodriguez-Viciana P
Proc Natl Acad Sci U S A; 2018 Nov; 115(45):E10576-E10585. PubMed ID: 30348783
[TBL] [Abstract][Full Text] [Related]
5. Expanding the molecular spectrum of pathogenic SHOC2 variants underlying Mazzanti syndrome.
Motta M; Solman M; Bonnard AA; Kuechler A; Pantaleoni F; Priolo M; Chandramouli B; Coppola S; Pizzi S; Zara E; Ferilli M; Kayserili H; Onesimo R; Leoni C; Brinkmann J; Vial Y; Kamphausen SB; Thomas-Teinturier C; Guimier A; Cordeddu V; Mazzanti L; Zampino G; Chillemi G; Zenker M; Cavé H; den Hertog J; Tartaglia M
Hum Mol Genet; 2022 Aug; 31(16):2766-2778. PubMed ID: 35348676
[TBL] [Abstract][Full Text] [Related]
6. Mutation analysis of the SHOC2 gene in Noonan-like syndrome and in hematologic malignancies.
Komatsuzaki S; Aoki Y; Niihori T; Okamoto N; Hennekam RC; Hopman S; Ohashi H; Mizuno S; Watanabe Y; Kamasaki H; Kondo I; Moriyama N; Kurosawa K; Kawame H; Okuyama R; Imaizumi M; Rikiishi T; Tsuchiya S; Kure S; Matsubara Y
J Hum Genet; 2010 Dec; 55(12):801-9. PubMed ID: 20882035
[TBL] [Abstract][Full Text] [Related]
7. Shoc2 is targeted to late endosomes and required for Erk1/2 activation in EGF-stimulated cells.
Galperin E; Abdelmoti L; Sorkin A
PLoS One; 2012; 7(5):e36469. PubMed ID: 22606262
[TBL] [Abstract][Full Text] [Related]
8. Functional Integration of the Conserved Domains of Shoc2 Scaffold.
Jeoung M; Abdelmoti L; Jang ER; Vander Kooi CW; Galperin E
PLoS One; 2013; 8(6):e66067. PubMed ID: 23805200
[TBL] [Abstract][Full Text] [Related]
9. Hematopoietic and neural crest defects in zebrafish shoc2 mutants: a novel vertebrate model for Noonan-like syndrome.
Jang H; Oakley E; Forbes-Osborne M; Kesler MV; Norcross R; Morris AC; Galperin E
Hum Mol Genet; 2019 Feb; 28(3):501-514. PubMed ID: 30329053
[TBL] [Abstract][Full Text] [Related]
10. M-Ras/Shoc2 signaling modulates E-cadherin turnover and cell-cell adhesion during collective cell migration.
Kota P; Terrell EM; Ritt DA; Insinna C; Westlake CJ; Morrison DK
Proc Natl Acad Sci U S A; 2019 Feb; 116(9):3536-3545. PubMed ID: 30808747
[TBL] [Abstract][Full Text] [Related]
11. Spatial control of Shoc2-scaffold-mediated ERK1/2 signaling requires remodeling activity of the ATPase PSMC5.
Jang ER; Jang H; Shi P; Popa G; Jeoung M; Galperin E
J Cell Sci; 2015 Dec; 128(23):4428-41. PubMed ID: 26519477
[TBL] [Abstract][Full Text] [Related]
12. Moyamoya syndrome in a patient with Noonan-like syndrome with loose anagen hair.
Choi JH; Oh MY; Yum MS; Lee BH; Kim GH; Yoo HW
Pediatr Neurol; 2015 Mar; 52(3):352-5. PubMed ID: 25563136
[TBL] [Abstract][Full Text] [Related]
13. The role of USP7 in the Shoc2-ERK1/2 signaling axis and Noonan-like syndrome with loose anagen hair.
Wilson P; Abdelmoti L; Norcross R; Jang ER; Palayam M; Galperin E
J Cell Sci; 2021 Nov; 134(21):. PubMed ID: 34553755
[TBL] [Abstract][Full Text] [Related]
14. A Leucine-Rich Repeat Protein Provides a SHOC2 the RAS Circuit: a Structure-Function Perspective.
Kwon JJ; Hahn WC
Mol Cell Biol; 2021 Mar; 41(4):. PubMed ID: 33526449
[TBL] [Abstract][Full Text] [Related]
15. SHOC2 complex-driven RAF dimerization selectively contributes to ERK pathway dynamics.
Boned Del Río I; Young LC; Sari S; Jones GG; Ringham-Terry B; Hartig N; Rejnowicz E; Lei W; Bhamra A; Surinova S; Rodriguez-Viciana P
Proc Natl Acad Sci U S A; 2019 Jul; 116(27):13330-13339. PubMed ID: 31213532
[TBL] [Abstract][Full Text] [Related]
16. Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex.
Kwon JJ; Hajian B; Bian Y; Young LC; Amor AJ; Fuller JR; Fraley CV; Sykes AM; So J; Pan J; Baker L; Lee SJ; Wheeler DB; Mayhew DL; Persky NS; Yang X; Root DE; Barsotti AM; Stamford AW; Perry CK; Burgin A; McCormick F; Lemke CT; Hahn WC; Aguirre AJ
Nature; 2022 Sep; 609(7926):408-415. PubMed ID: 35831509
[TBL] [Abstract][Full Text] [Related]
17. GH Therapy and first final height data in Noonan-like syndrome with loose anagen hair (Mazzanti syndrome).
Mazzanti L; Tamburrino F; Scarano E; Perri A; Vestrucci B; Guidetti M; Rossi C; Tartaglia M
Am J Med Genet A; 2013 Nov; 161A(11):2756-61. PubMed ID: 24124081
[TBL] [Abstract][Full Text] [Related]
18. A novel rasopathy caused by recurrent de novo missense mutations in PPP1CB closely resembles Noonan syndrome with loose anagen hair.
Gripp KW; Aldinger KA; Bennett JT; Baker L; Tusi J; Powell-Hamilton N; Stabley D; Sol-Church K; Timms AE; Dobyns WB
Am J Med Genet A; 2016 Sep; 170(9):2237-47. PubMed ID: 27264673
[TBL] [Abstract][Full Text] [Related]
19. Phenotypic variability associated with the invariant SHOC2 c.4A>G (p.Ser2Gly) missense mutation.
Baldassarre G; Mussa A; Banaudi E; Rossi C; Tartaglia M; Silengo M; Ferrero GB
Am J Med Genet A; 2014 Dec; 164A(12):3120-5. PubMed ID: 25331583
[TBL] [Abstract][Full Text] [Related]
20. HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold.
Jang ER; Shi P; Bryant J; Chen J; Dukhande V; Gentry MS; Jang H; Jeoung M; Galperin E
Mol Cell Biol; 2014 Oct; 34(19):3579-93. PubMed ID: 25022756
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]