414 related articles for article (PubMed ID: 27468060)
1. Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
Kühnen P; Clément K; Wiegand S; Blankenstein O; Gottesdiener K; Martini LL; Mai K; Blume-Peytavi U; Grüters A; Krude H
N Engl J Med; 2016 Jul; 375(3):240-6. PubMed ID: 27468060
[TBL] [Abstract][Full Text] [Related]
2. Hormone-Replacement Therapy for Melanocyte-Stimulating Hormone Deficiency.
Reitman ML
N Engl J Med; 2016 Jul; 375(3):278-9. PubMed ID: 27468065
[No Abstract] [Full Text] [Related]
3. Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials.
Clément K; van den Akker E; Argente J; Bahm A; Chung WK; Connors H; De Waele K; Farooqi IS; Gonneau-Lejeune J; Gordon G; Kohlsdorf K; Poitou C; Puder L; Swain J; Stewart M; Yuan G; Wabitsch M; Kühnen P;
Lancet Diabetes Endocrinol; 2020 Dec; 8(12):960-970. PubMed ID: 33137293
[TBL] [Abstract][Full Text] [Related]
4. Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency.
Collet TH; Dubern B; Mokrosinski J; Connors H; Keogh JM; Mendes de Oliveira E; Henning E; Poitou-Bernert C; Oppert JM; Tounian P; Marchelli F; Alili R; Le Beyec J; Pépin D; Lacorte JM; Gottesdiener A; Bounds R; Sharma S; Folster C; Henderson B; O'Rahilly S; Stoner E; Gottesdiener K; Panaro BL; Cone RD; Clément K; Farooqi IS; Van der Ploeg LHT
Mol Metab; 2017 Oct; 6(10):1321-1329. PubMed ID: 29031731
[TBL] [Abstract][Full Text] [Related]
5. A novel mutation in the proopiomelanocortin (POMC) gene of a Hispanic child: metformin treatment shows a beneficial impact on the body mass index.
Hilado MA; Randhawa RS
J Pediatr Endocrinol Metab; 2018 Jul; 31(7):815-819. PubMed ID: 29858905
[TBL] [Abstract][Full Text] [Related]
6. Obesity and Hyperphagia With Increased Defective ACTH: A Novel POMC Variant.
van der Valk ES; Kleinendorst L; Delhanty PJD; van der Voorn B; Visser JA; van Haelst MM; de Graaff LCG; Huisman M; White A; Ito S; Wakamatsu K; de Rijke YB; van den Akker ELT; Iyer AM; van Rossum EFC
J Clin Endocrinol Metab; 2022 Aug; 107(9):e3699-e3704. PubMed ID: 35737586
[TBL] [Abstract][Full Text] [Related]
7. Understanding the Patient Experience of Hunger and Improved Quality of Life with Setmelanotide Treatment in POMC and LEPR Deficiencies.
Wabitsch M; Fehnel S; Mallya UG; Sluga-O'Callaghan M; Richardson D; Price M; Kühnen P
Adv Ther; 2022 Apr; 39(4):1772-1783. PubMed ID: 35192151
[TBL] [Abstract][Full Text] [Related]
8. Two Cases With an Early Presented Proopiomelanocortin Deficiency-A Long-Term Follow-Up and Systematic Literature Review.
Gregoric N; Groselj U; Bratina N; Debeljak M; Zerjav Tansek M; Suput Omladic J; Kovac J; Battelino T; Kotnik P; Avbelj Stefanija M
Front Endocrinol (Lausanne); 2021; 12():689387. PubMed ID: 34177811
[TBL] [Abstract][Full Text] [Related]
9. Pro-opiomelanocortin (POMC) deficiency and peripheral melanocortins in obesity.
Zemel MB; Shi H
Nutr Rev; 2000 Jun; 58(6):177-80. PubMed ID: 10885325
[TBL] [Abstract][Full Text] [Related]
10. Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin.
Yaswen L; Diehl N; Brennan MB; Hochgeschwender U
Nat Med; 1999 Sep; 5(9):1066-70. PubMed ID: 10470087
[TBL] [Abstract][Full Text] [Related]
11. Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10.
Krude H; Biebermann H; Schnabel D; Tansek MZ; Theunissen P; Mullis PE; Grüters A
J Clin Endocrinol Metab; 2003 Oct; 88(10):4633-40. PubMed ID: 14557433
[TBL] [Abstract][Full Text] [Related]
12. Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment.
Ayers KL; Glicksberg BS; Garfield AS; Longerich S; White JA; Yang P; Du L; Chittenden TW; Gulcher JR; Roy S; Fiedorek F; Gottesdiener K; Cohen S; North KE; Schadt EE; Li SD; Chen R; Van der Ploeg LHT
J Clin Endocrinol Metab; 2018 Jul; 103(7):2601-2612. PubMed ID: 29726959
[TBL] [Abstract][Full Text] [Related]
13. Therapeutic Strategies Against Metabolic Imbalance in a Male Mouse Model With 5-HT2CR Loss-of-Function.
Liu H; Liu Z; Wong HK; Xu N; Liu Q; Li Y; Liu Y; Wong H; Burt ME; Jossy SV; Han J; He Y
Endocrinology; 2024 May; 165(7):. PubMed ID: 38815086
[TBL] [Abstract][Full Text] [Related]
14. Quality of life outcomes in two phase 3 trials of setmelanotide in patients with obesity due to LEPR or POMC deficiency.
Kühnen P; Wabitsch M; von Schnurbein J; Chirila C; Mallya UG; Callahan P; Gnanasakthy A; Poitou C; Krabusch PM; Stewart M; Clément K
Orphanet J Rare Dis; 2022 Feb; 17(1):38. PubMed ID: 35123544
[TBL] [Abstract][Full Text] [Related]
15. Setmelanotide: First Approval.
Markham A
Drugs; 2021 Feb; 81(3):397-403. PubMed ID: 33638809
[TBL] [Abstract][Full Text] [Related]
16. Magel2-null mice are hyper-responsive to setmelanotide, a melanocortin 4 receptor agonist.
Bischof JM; Van Der Ploeg LH; Colmers WF; Wevrick R
Br J Pharmacol; 2016 Sep; 173(17):2614-21. PubMed ID: 27339818
[TBL] [Abstract][Full Text] [Related]
17. Melanocortin signaling is decreased during neurotoxin-induced transient hyperphagia and increased body-weight gain.
Dube MG; Pu S; Kalra SP; Kalra PS
Peptides; 2000 Jun; 21(6):793-801. PubMed ID: 10958999
[TBL] [Abstract][Full Text] [Related]
18. Melanocortin-4 Receptor Signalling: Importance for Weight Regulation and Obesity Treatment.
Kühnen P; Krude H; Biebermann H
Trends Mol Med; 2019 Feb; 25(2):136-148. PubMed ID: 30642682
[TBL] [Abstract][Full Text] [Related]
19. The melanocortin pathway and energy homeostasis: From discovery to obesity therapy.
Yeo GSH; Chao DHM; Siegert AM; Koerperich ZM; Ericson MD; Simonds SE; Larson CM; Luquet S; Clarke I; Sharma S; Clément K; Cowley MA; Haskell-Luevano C; Van Der Ploeg L; Adan RAH
Mol Metab; 2021 Jun; 48():101206. PubMed ID: 33684608
[TBL] [Abstract][Full Text] [Related]
20. A case of early-onset obesity, hypocortisolism, and skin pigmentation problem due to a novel homozygous mutation in the proopiomelanocortin (POMC) gene in an Indian boy.
Hung CN; Poon WT; Lee CY; Law CY; Chan AY
J Pediatr Endocrinol Metab; 2012; 25(1-2):175-9. PubMed ID: 22570972
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]