307 related articles for article (PubMed ID: 27470268)
1. Ubiquitin Ligase, Fbw7, Targets CDX2 for Degradation via Two Phosphodegron Motifs in a GSK3β-Dependent Manner.
Kumar Y; Shukla N; Thacker G; Kapoor I; Lochab S; Bhatt ML; Chattopadhyay N; Sanyal S; Trivedi AK
Mol Cancer Res; 2016 Nov; 14(11):1097-1109. PubMed ID: 27470268
[TBL] [Abstract][Full Text] [Related]
2. The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs.
Liu N; Li H; Li S; Shen M; Xiao N; Chen Y; Wang Y; Wang W; Wang R; Wang Q; Sun J; Wang P
J Biol Chem; 2010 Jun; 285(24):18858-67. PubMed ID: 20388706
[TBL] [Abstract][Full Text] [Related]
3. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
Nakajima T; Kitagawa K; Ohhata T; Sakai S; Uchida C; Shibata K; Minegishi N; Yumimoto K; Nakayama KI; Masumoto K; Katou F; Niida H; Kitagawa M
J Biol Chem; 2015 Apr; 290(16):10368-81. PubMed ID: 25670854
[TBL] [Abstract][Full Text] [Related]
4. E3 Ubiquitin Ligase Fbw7 Negatively Regulates Osteoblast Differentiation by Targeting Runx2 for Degradation.
Kumar Y; Kapoor I; Khan K; Thacker G; Khan MP; Shukla N; Kanaujiya JK; Sanyal S; Chattopadhyay N; Trivedi AK
J Biol Chem; 2015 Dec; 290(52):30975-87. PubMed ID: 26542806
[TBL] [Abstract][Full Text] [Related]
5. E3 ubiquitin ligase Fbw7 negatively regulates granulocytic differentiation by targeting G-CSFR for degradation.
Lochab S; Pal P; Kapoor I; Kanaujiya JK; Sanyal S; Behre G; Trivedi AK
Biochim Biophys Acta; 2013 Dec; 1833(12):2639-2652. PubMed ID: 23820376
[TBL] [Abstract][Full Text] [Related]
6. A colon cancer-derived mutant of Krüppel-like factor 5 (KLF5) is resistant to degradation by glycogen synthase kinase 3β (GSK3β) and the E3 ubiquitin ligase F-box and WD repeat domain-containing 7α (FBW7α).
Bialkowska AB; Liu Y; Nandan MO; Yang VW
J Biol Chem; 2014 Feb; 289(9):5997-6005. PubMed ID: 24398687
[TBL] [Abstract][Full Text] [Related]
7. The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation.
Zhao D; Zheng HQ; Zhou Z; Chen C
Cancer Res; 2010 Jun; 70(11):4728-38. PubMed ID: 20484041
[TBL] [Abstract][Full Text] [Related]
8. Fbw7 dimerization determines the specificity and robustness of substrate degradation.
Welcker M; Larimore EA; Swanger J; Bengoechea-Alonso MT; Grim JE; Ericsson J; Zheng N; Clurman BE
Genes Dev; 2013 Dec; 27(23):2531-6. PubMed ID: 24298052
[TBL] [Abstract][Full Text] [Related]
9. Stringent Control of NFE2L3 (Nuclear Factor, Erythroid 2-Like 3; NRF3) Protein Degradation by FBW7 (F-box/WD Repeat-containing Protein 7) and Glycogen Synthase Kinase 3 (GSK3).
Kannan MB; Dodard-Friedman I; Blank V
J Biol Chem; 2015 Oct; 290(43):26292-302. PubMed ID: 26306035
[TBL] [Abstract][Full Text] [Related]
10. FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation.
Wang R; Wang Y; Liu N; Ren C; Jiang C; Zhang K; Yu S; Chen Y; Tang H; Deng Q; Fu C; Wang Y; Li R; Liu M; Pan W; Wang P
Cell Res; 2013 Jun; 23(6):803-19. PubMed ID: 23507969
[TBL] [Abstract][Full Text] [Related]
11. Negative regulation of HIF-1α by an FBW7-mediated degradation pathway during hypoxia.
Cassavaugh JM; Hale SA; Wellman TL; Howe AK; Wong C; Lounsbury KM
J Cell Biochem; 2011 Dec; 112(12):3882-90. PubMed ID: 21964756
[TBL] [Abstract][Full Text] [Related]
12. SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage.
Hong X; Liu W; Song R; Shah JJ; Feng X; Tsang CK; Morgan KM; Bunting SF; Inuzuka H; Zheng XF; Shen Z; Sabaawy HE; Liu L; Pine SR
Nucleic Acids Res; 2016 Oct; 44(18):8855-8869. PubMed ID: 27566146
[TBL] [Abstract][Full Text] [Related]
13. Ubiquitin ligase Fbw7 restricts the replication of hepatitis C virus by targeting NS5B for ubiquitination and degradation.
Chen J; Wu X; Chen S; Chen S; Xiang N; Chen Y; Guo D
Biochem Biophys Res Commun; 2016 Feb; 470(3):697-703. PubMed ID: 26774344
[TBL] [Abstract][Full Text] [Related]
14. CDK5/FBW7-dependent ubiquitination and degradation of EZH2 inhibits pancreatic cancer cell migration and invasion.
Jin X; Yang C; Fan P; Xiao J; Zhang W; Zhan S; Liu T; Wang D; Wu H
J Biol Chem; 2017 Apr; 292(15):6269-6280. PubMed ID: 28242758
[TBL] [Abstract][Full Text] [Related]
15. FBW7 targets KLF10 for ubiquitin-dependent degradation.
Yu S; Wang F; Tan X; Gao GL; Pan WJ; Luan Y; Ge X
Biochem Biophys Res Commun; 2018 Jan; 495(2):2092-2097. PubMed ID: 29198712
[TBL] [Abstract][Full Text] [Related]
16. The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome-mediated proteolysis.
Biswas M; Phan D; Watanabe M; Chan JY
J Biol Chem; 2011 Nov; 286(45):39282-9. PubMed ID: 21953459
[TBL] [Abstract][Full Text] [Related]
17. SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
Inuzuka H; Shaik S; Onoyama I; Gao D; Tseng A; Maser RS; Zhai B; Wan L; Gutierrez A; Lau AW; Xiao Y; Christie AL; Aster J; Settleman J; Gygi SP; Kung AL; Look T; Nakayama KI; DePinho RA; Wei W
Nature; 2011 Mar; 471(7336):104-9. PubMed ID: 21368833
[TBL] [Abstract][Full Text] [Related]
18. SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction.
Fukushima H; Matsumoto A; Inuzuka H; Zhai B; Lau AW; Wan L; Gao D; Shaik S; Yuan M; Gygi SP; Jimi E; Asara JM; Nakayama K; Nakayama KI; Wei W
Cell Rep; 2012 May; 1(5):434-43. PubMed ID: 22708077
[TBL] [Abstract][Full Text] [Related]
19. GSK-3β regulates cell growth, migration, and angiogenesis via Fbw7 and USP28-dependent degradation of HIF-1α.
Flügel D; Görlach A; Kietzmann T
Blood; 2012 Feb; 119(5):1292-301. PubMed ID: 22144179
[TBL] [Abstract][Full Text] [Related]
20. Isoform-specific SCF(Fbw7) ubiquitination mediates differential regulation of PGC-1α.
Trausch-Azar JS; Abed M; Orian A; Schwartz AL
J Cell Physiol; 2015 Apr; 230(4):842-52. PubMed ID: 25204433
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
