233 related articles for article (PubMed ID: 27470546)
1. Synergistic cytotoxicity of BIIB021 with triptolide through suppression of PI3K/Akt/mTOR and NF-κB signal pathways in thyroid carcinoma cells.
Kim SH; Kang JG; Kim CS; Ihm SH; Choi MG; Yoo HJ; Lee SJ
Biomed Pharmacother; 2016 Oct; 83():22-32. PubMed ID: 27470546
[TBL] [Abstract][Full Text] [Related]
2. Heat Shock Protein 90 Inhibitors AUY922, BIIB021 and SNX5422 Induce Bim-mediated Death of Thyroid Carcinoma Cells.
Kim SH; Cho YK; Huh JH; Kang JG; Ihm SH; Choi MG; Lee SJ
Anticancer Res; 2020 Nov; 40(11):6137-6150. PubMed ID: 33109551
[TBL] [Abstract][Full Text] [Related]
3. Hsp90 inhibitor BIIB021 enhances triptolide-induced apoptosis of human T-cell acute lymphoblastic leukemia cells in vitro mainly by disrupting p53-MDM2 balance.
Li M; Zhang X; Zhou WJ; Chen YH; Liu H; Liu L; Yang CM; Qan WB
Acta Pharmacol Sin; 2013 Dec; 34(12):1545-53. PubMed ID: 24241349
[TBL] [Abstract][Full Text] [Related]
4. The heat shock protein 90 inhibitor SNX5422 has a synergistic activity with histone deacetylase inhibitors in induction of death of anaplastic thyroid carcinoma cells.
Kim SH; Kang JG; Kim CS; Ihm SH; Choi MG; Yoo HJ; Lee SJ
Endocrine; 2016 Feb; 51(2):274-82. PubMed ID: 26219406
[TBL] [Abstract][Full Text] [Related]
5. Novel heat shock protein 90 inhibitor NVP-AUY922 synergizes with the histone deacetylase inhibitor PXD101 in induction of death of anaplastic thyroid carcinoma cells.
Kim SH; Kang JG; Kim CS; Ihm SH; Choi MG; Yoo HJ; Lee SJ
J Clin Endocrinol Metab; 2015 Feb; 100(2):E253-61. PubMed ID: 25389633
[TBL] [Abstract][Full Text] [Related]
6. Hsp90 inhibitor, BIIB021, induces apoptosis and autophagy by regulating mTOR-Ulk1 pathway in imatinib-sensitive and -resistant chronic myeloid leukemia cells.
He W; Ye X; Huang X; Lel W; You L; Wang L; Chen X; Qian W
Int J Oncol; 2016 Apr; 48(4):1710-20. PubMed ID: 26892093
[TBL] [Abstract][Full Text] [Related]
7. Triptolide inhibits PDGF-induced proliferation of ASMCs through G0/G1 cell cycle arrest and suppression of the AKT/NF-κB/cyclinD1 signaling pathway.
He S; Chen M; Lin X; Lv Z; Liang R; Huang L
Eur J Pharmacol; 2020 Jan; 867():172811. PubMed ID: 31756335
[TBL] [Abstract][Full Text] [Related]
8. NF-κB signaling inhibition and anticancer activities of LLDT-246 on human colorectal cancer HCT-116 cells in vitro.
Li M; Wang X; Liu M; Qi X; Li J
Biomed Pharmacother; 2014 Jun; 68(5):527-35. PubMed ID: 24986326
[TBL] [Abstract][Full Text] [Related]
9. Heat shock protein 90 inhibitor BIIB021 (CNF2024) depletes NF-kappaB and sensitizes Hodgkin's lymphoma cells for natural killer cell-mediated cytotoxicity.
Böll B; Eltaib F; Reiners KS; von Tresckow B; Tawadros S; Simhadri VR; Burrows FJ; Lundgren K; Hansen HP; Engert A; von Strandmann EP
Clin Cancer Res; 2009 Aug; 15(16):5108-16. PubMed ID: 19671844
[TBL] [Abstract][Full Text] [Related]
10. Negative regulation of PI3K/AKT/mTOR axis regulates fibroblast proliferation, apoptosis and autophagy play a vital role in triptolide-induced epidural fibrosis reduction.
Dai J; Sun Y; Chen D; Zhang Y; Yan L; Li X; Wang J
Eur J Pharmacol; 2019 Dec; 864():172724. PubMed ID: 31600493
[TBL] [Abstract][Full Text] [Related]
11. Triptolide sensitizes human breast cancer cells to tumor necrosis factor‑α‑induced apoptosis by inhibiting activation of the nuclear factor‑κB pathway.
Cheng X; Shi W; Zhao C; Zhang D; Liang P; Wang G; Lu L
Mol Med Rep; 2016 Apr; 13(4):3257-64. PubMed ID: 26935527
[TBL] [Abstract][Full Text] [Related]
12. Enigma Plays Roles in Survival of Thyroid Carcinoma Cells through PI3K/AKT Signaling and Survivin.
Kim YJ; Hwang HJ; Kang JG; Kim CS; Ihm SH; Choi MG; Lee SJ
Anticancer Res; 2018 Jun; 38(6):3515-3525. PubMed ID: 29848705
[TBL] [Abstract][Full Text] [Related]
13. Triptolide induces apoptosis in human anaplastic thyroid carcinoma cells by a p53-independent but NF-kappaB-related mechanism.
Zhu W; Hu H; Qiu P; Yan G
Oncol Rep; 2009 Dec; 22(6):1397-401. PubMed ID: 19885592
[TBL] [Abstract][Full Text] [Related]
14. Gemigliptin, a novel dipeptidyl peptidase-IV inhibitor, exerts a synergistic cytotoxicity with the histone deacetylase inhibitor PXD101 in thyroid carcinoma cells.
Kim SH; Kang JG; Kim CS; Ihm SH; Choi MG; Yoo HJ; Lee SJ
J Endocrinol Invest; 2018 Jun; 41(6):677-689. PubMed ID: 29147952
[TBL] [Abstract][Full Text] [Related]
15. Triptolide overcomes dexamethasone resistance and enhanced PS-341-induced apoptosis via PI3k/Akt/NF-kappaB pathways in human multiple myeloma cells.
Yang M; Huang J; Pan HZ; Jin J
Int J Mol Med; 2008 Oct; 22(4):489-96. PubMed ID: 18813856
[TBL] [Abstract][Full Text] [Related]
16. Biochemical and computational evaluation of Triptolide-induced cytotoxicity against NSCLC.
Hamdi AM; Jiang ZZ; Guerram M; Yousef BA; Hassan HM; Ling JW; Zhang LY
Biomed Pharmacother; 2018 Jul; 103():1557-1566. PubMed ID: 29864943
[TBL] [Abstract][Full Text] [Related]
17. Synthetic lethal interaction between PI3K/Akt/mTOR and Ras/MEK/ERK pathway inhibition in rhabdomyosarcoma.
Guenther MK; Graab U; Fulda S
Cancer Lett; 2013 Sep; 337(2):200-9. PubMed ID: 23684925
[TBL] [Abstract][Full Text] [Related]
18. The dipeptidyl peptidase-IV inhibitor gemigliptin alone or in combination with NVP-AUY922 has a cytotoxic activity in thyroid carcinoma cells.
Kim SH; Kang JG; Kim CS; Ihm SH; Choi MG; Yoo HJ; Lee SJ
Tumour Biol; 2017 Oct; 39(10):1010428317722068. PubMed ID: 28982310
[TBL] [Abstract][Full Text] [Related]
19. A purine scaffold HSP90 inhibitor BIIB021 has selective activity against KSHV-associated primary effusion lymphoma and blocks vFLIP K13-induced NF-κB.
Gopalakrishnan R; Matta H; Chaudhary PM
Clin Cancer Res; 2013 Sep; 19(18):5016-26. PubMed ID: 23881928
[TBL] [Abstract][Full Text] [Related]
20. The synergistic anti-proliferative effect of the combination of diosmin and BEZ-235 (dactolisib) on the HCT-116 colorectal cancer cell line occurs through inhibition of the PI3K/Akt/mTOR/NF-κB axis.
Helmy MW; Ghoneim AI; Katary MA; Elmahdy RK
Mol Biol Rep; 2020 Mar; 47(3):2217-2230. PubMed ID: 32088816
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]