212 related articles for article (PubMed ID: 27475227)
1. Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement.
Lee SH; Le Pichon CE; Adolfsson O; Gafner V; Pihlgren M; Lin H; Solanoy H; Brendza R; Ngu H; Foreman O; Chan R; Ernst JA; DiCara D; Hotzel I; Srinivasan K; Hansen DV; Atwal J; Lu Y; Bumbaca D; Pfeifer A; Watts RJ; Muhs A; Scearce-Levie K; Ayalon G
Cell Rep; 2016 Aug; 16(6):1690-1700. PubMed ID: 27475227
[TBL] [Abstract][Full Text] [Related]
2. Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes.
Andersson CR; Falsig J; Stavenhagen JB; Christensen S; Kartberg F; Rosenqvist N; Finsen B; Pedersen JT
Sci Rep; 2019 Mar; 9(1):4658. PubMed ID: 30874605
[TBL] [Abstract][Full Text] [Related]
3. Cell-based Assay to Study Antibody-mediated Tau Clearance by Microglia.
De Marco D; Taggenbrock R; Crespo R; Koudstaal W; Ramsburg E; Apetri A
J Vis Exp; 2018 Nov; (141):. PubMed ID: 30474638
[TBL] [Abstract][Full Text] [Related]
4. Distinct Therapeutic Mechanisms of Tau Antibodies: Promoting Microglial Clearance Versus Blocking Neuronal Uptake.
Funk KE; Mirbaha H; Jiang H; Holtzman DM; Diamond MI
J Biol Chem; 2015 Aug; 290(35):21652-62. PubMed ID: 26126828
[TBL] [Abstract][Full Text] [Related]
5. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
[TBL] [Abstract][Full Text] [Related]
6. Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro.
Nobuhara CK; DeVos SL; Commins C; Wegmann S; Moore BD; Roe AD; Costantino I; Frosch MP; Pitstick R; Carlson GA; Hock C; Nitsch RM; Montrasio F; Grimm J; Cheung AE; Dunah AW; Wittmann M; Bussiere T; Weinreb PH; Hyman BT; Takeda S
Am J Pathol; 2017 Jun; 187(6):1399-1412. PubMed ID: 28408124
[TBL] [Abstract][Full Text] [Related]
7. TREM2 modifies microglial phenotype and provides neuroprotection in P301S tau transgenic mice.
Jiang T; Zhang YD; Chen Q; Gao Q; Zhu XC; Zhou JS; Shi JQ; Lu H; Tan L; Yu JT
Neuropharmacology; 2016 Jun; 105():196-206. PubMed ID: 26802771
[TBL] [Abstract][Full Text] [Related]
8. Acyl-coenzyme A:cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at the presymptomatic stage.
Shibuya Y; Niu Z; Bryleva EY; Harris BT; Murphy SR; Kheirollah A; Bowen ZD; Chang CCY; Chang TY
Neurobiol Aging; 2015 Jul; 36(7):2248-2259. PubMed ID: 25930235
[TBL] [Abstract][Full Text] [Related]
9. Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody.
Luo W; Liu W; Hu X; Hanna M; Caravaca A; Paul SM
Sci Rep; 2015 Jun; 5():11161. PubMed ID: 26057852
[TBL] [Abstract][Full Text] [Related]
10. Depletion of microglia and inhibition of exosome synthesis halt tau propagation.
Asai H; Ikezu S; Tsunoda S; Medalla M; Luebke J; Haydar T; Wolozin B; Butovsky O; Kügler S; Ikezu T
Nat Neurosci; 2015 Nov; 18(11):1584-93. PubMed ID: 26436904
[TBL] [Abstract][Full Text] [Related]
11. Age-dependent effects of microglial inhibition in vivo on Alzheimer's disease neuropathology using bioactive-conjugated iron oxide nanoparticles.
Glat M; Skaat H; Menkes-Caspi N; Margel S; Stern EA
J Nanobiotechnology; 2013 Sep; 11():32. PubMed ID: 24059692
[TBL] [Abstract][Full Text] [Related]
12. TREM2 Ameliorates Neuronal Tau Pathology Through Suppression of Microglial Inflammatory Response.
Jiang T; Zhang YD; Gao Q; Ou Z; Gong PY; Shi JQ; Wu L; Zhou JS
Inflammation; 2018 Jun; 41(3):811-823. PubMed ID: 29362997
[TBL] [Abstract][Full Text] [Related]
13. Absence of CX3CR1 impairs the internalization of Tau by microglia.
Bolós M; Llorens-Martín M; Perea JR; Jurado-Arjona J; Rábano A; Hernández F; Avila J
Mol Neurodegener; 2017 Aug; 12(1):59. PubMed ID: 28810892
[TBL] [Abstract][Full Text] [Related]
14. Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway.
Li Y; Liu L; Barger SW; Griffin WS
J Neurosci; 2003 Mar; 23(5):1605-11. PubMed ID: 12629164
[TBL] [Abstract][Full Text] [Related]
15. Deglycosylated anti-amyloid beta antibodies reduce microglial phagocytosis and cytokine production while retaining the capacity to induce amyloid beta sequestration.
Takata K; Hirata-Fukae C; Becker AG; Chishiro S; Gray AJ; Nishitomi K; Franz AH; Sakaguchi G; Kato A; Mattson MP; Laferla FM; Aisen PS; Kitamura Y; Matsuoka Y
Eur J Neurosci; 2007 Nov; 26(9):2458-68. PubMed ID: 17970733
[TBL] [Abstract][Full Text] [Related]
16. Direct Evidence of Internalization of Tau by Microglia In Vitro and In Vivo.
Bolós M; Llorens-Martín M; Jurado-Arjona J; Hernández F; Rábano A; Avila J
J Alzheimers Dis; 2016; 50(1):77-87. PubMed ID: 26638867
[TBL] [Abstract][Full Text] [Related]
17. Measuring Antibody-Mediated Tau Fibril Uptake in Microglia by Flow Cytometry.
Funk KE
Methods Mol Biol; 2024; 2754():437-444. PubMed ID: 38512680
[TBL] [Abstract][Full Text] [Related]
18. Therapeutic antibody targeting microtubule-binding domain prevents neuronal internalization of extracellular tau via masking neuron surface proteoglycans.
Weisová P; Cehlár O; Škrabana R; Žilková M; Filipčík P; Kováčech B; Prčina M; Wojčiaková Ľ; Fialová Ľ; Smolek T; Kontseková E; Žilka N; Novák M
Acta Neuropathol Commun; 2019 Aug; 7(1):129. PubMed ID: 31391090
[TBL] [Abstract][Full Text] [Related]
19. Immunotherapy for Alzheimer's disease.
Wang W; Fan L; Xu D; Wen Z; Yu R; Ma Q
Acta Biochim Biophys Sin (Shanghai); 2012 Oct; 44(10):807-14. PubMed ID: 22899646
[TBL] [Abstract][Full Text] [Related]
20. Accumulation of tau induced in neurites by microglial proinflammatory mediators.
Gorlovoy P; Larionov S; Pham TT; Neumann H
FASEB J; 2009 Aug; 23(8):2502-13. PubMed ID: 19289607
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
