BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

431 related articles for article (PubMed ID: 27477910)

  • 1. DNA Breaks and End Resection Measured Genome-wide by End Sequencing.
    Canela A; Sridharan S; Sciascia N; Tubbs A; Meltzer P; Sleckman BP; Nussenzweig A
    Mol Cell; 2016 Sep; 63(5):898-911. PubMed ID: 27477910
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Endonuclease G plays a role in immunoglobulin class switch DNA recombination by introducing double-strand breaks in switch regions.
    Zan H; Zhang J; Al-Qahtani A; Pone EJ; White CA; Lee D; Yel L; Mai T; Casali P
    Mol Immunol; 2011 Jan; 48(4):610-22. PubMed ID: 21111482
    [TBL] [Abstract][Full Text] [Related]  

  • 3. END-seq: An Unbiased, High-Resolution, and Genome-Wide Approach to Map DNA Double-Strand Breaks and Resection in Human Cells.
    Wong N; John S; Nussenzweig A; Canela A
    Methods Mol Biol; 2021; 2153():9-31. PubMed ID: 32840769
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Histone H2AX stabilizes broken DNA strands to suppress chromosome breaks and translocations during V(D)J recombination.
    Yin B; Savic V; Juntilla MM; Bredemeyer AL; Yang-Iott KS; Helmink BA; Koretzky GA; Sleckman BP; Bassing CH
    J Exp Med; 2009 Nov; 206(12):2625-39. PubMed ID: 19887394
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.
    Dong J; Panchakshari RA; Zhang T; Zhang Y; Hu J; Volpi SA; Meyers RM; Ho YJ; Du Z; Robbiani DF; Meng F; Gostissa M; Nussenzweig MC; Manis JP; Alt FW
    Nature; 2015 Sep; 525(7567):134-139. PubMed ID: 26308889
    [TBL] [Abstract][Full Text] [Related]  

  • 6. H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes.
    Helmink BA; Tubbs AT; Dorsett Y; Bednarski JJ; Walker LM; Feng Z; Sharma GG; McKinnon PJ; Zhang J; Bassing CH; Sleckman BP
    Nature; 2011 Jan; 469(7329):245-9. PubMed ID: 21160476
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals.
    Bednarski JJ; Pandey R; Schulte E; White LS; Chen BR; Sandoval GJ; Kohyama M; Haldar M; Nickless A; Trott A; Cheng G; Murphy KM; Bassing CH; Payton JE; Sleckman BP
    J Exp Med; 2016 Feb; 213(2):209-23. PubMed ID: 26834154
    [TBL] [Abstract][Full Text] [Related]  

  • 8. IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances.
    Gostissa M; Schwer B; Chang A; Dong J; Meyers RM; Marecki GT; Choi VW; Chiarle R; Zarrin AA; Alt FW
    Proc Natl Acad Sci U S A; 2014 Feb; 111(7):2644-9. PubMed ID: 24550291
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DSB structure impacts DNA recombination leading to class switching and chromosomal translocations in human B cells.
    So CC; Martin A
    PLoS Genet; 2019 Apr; 15(4):e1008101. PubMed ID: 30946744
    [TBL] [Abstract][Full Text] [Related]  

  • 10. AID- and Ung-dependent generation of staggered double-strand DNA breaks in immunoglobulin class switch DNA recombination: a post-cleavage role for AID.
    Zan H; Casali P
    Mol Immunol; 2008 Nov; 46(1):45-61. PubMed ID: 18760480
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.
    Hasham MG; Snow KJ; Donghia NM; Branca JA; Lessard MD; Stavnezer J; Shopland LS; Mills KD
    J Immunol; 2012 Sep; 189(5):2374-82. PubMed ID: 22826323
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks.
    Zha S; Guo C; Boboila C; Oksenych V; Cheng HL; Zhang Y; Wesemann DR; Yuen G; Patel H; Goff PH; Dubois RL; Alt FW
    Nature; 2011 Jan; 469(7329):250-4. PubMed ID: 21160472
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ku70 suppresses alternative end joining in G1-arrested progenitor B cells.
    Liang Z; Kumar V; Le Bouteiller M; Zurita J; Kenrick J; Lin SG; Lou J; Hu J; Ye AY; Boboila C; Alt FW; Frock RL
    Proc Natl Acad Sci U S A; 2021 May; 118(21):. PubMed ID: 34006647
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ATR kinase activity promotes antibody class switch recombination in B cells through cell cycle regulation without suppressing DSB resection and microhomology usage.
    Sun X; Liu M; Bai J; Xu J; Zhu C; Dong J; Chen C
    J Leukoc Biol; 2021 Dec; 110(6):1101-1112. PubMed ID: 33884660
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycle.
    Yamane A; Robbiani DF; Resch W; Bothmer A; Nakahashi H; Oliveira T; Rommel PC; Brown EJ; Nussenzweig A; Nussenzweig MC; Casellas R
    Cell Rep; 2013 Jan; 3(1):138-47. PubMed ID: 23291097
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks.
    Helmink BA; Bredemeyer AL; Lee BS; Huang CY; Sharma GG; Walker LM; Bednarski JJ; Lee WL; Pandita TK; Bassing CH; Sleckman BP
    J Exp Med; 2009 Mar; 206(3):669-79. PubMed ID: 19221393
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination.
    Chahwan R; van Oers JM; Avdievich E; Zhao C; Edelmann W; Scharff MD; Roa S
    J Exp Med; 2012 Apr; 209(4):671-8. PubMed ID: 22451719
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1.
    Bothmer A; Robbiani DF; Di Virgilio M; Bunting SF; Klein IA; Feldhahn N; Barlow J; Chen HT; Bosque D; Callen E; Nussenzweig A; Nussenzweig MC
    Mol Cell; 2011 May; 42(3):319-29. PubMed ID: 21549309
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA double-strand break response factors influence end-joining features of IgH class switch and general translocation junctions.
    Panchakshari RA; Zhang X; Kumar V; Du Z; Wei PC; Kao J; Dong J; Alt FW
    Proc Natl Acad Sci U S A; 2018 Jan; 115(4):762-767. PubMed ID: 29311308
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The complexity of DNA double strand breaks is a critical factor enhancing end-resection.
    Yajima H; Fujisawa H; Nakajima NI; Hirakawa H; Jeggo PA; Okayasu R; Fujimori A
    DNA Repair (Amst); 2013 Nov; 12(11):936-46. PubMed ID: 24041488
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.