These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

447 related articles for article (PubMed ID: 27481946)

  • 1. PREX1 Protein Function Is Negatively Regulated Downstream of Receptor Tyrosine Kinase Activation by p21-activated Kinases (PAKs).
    Barrows D; He JZ; Parsons R
    J Biol Chem; 2016 Sep; 291(38):20042-54. PubMed ID: 27481946
    [TBL] [Abstract][Full Text] [Related]  

  • 2. p21-activated Kinases (PAKs) Mediate the Phosphorylation of PREX2 Protein to Initiate Feedback Inhibition of Rac1 GTPase.
    Barrows D; Schoenfeld SM; Hodakoski C; Silkov A; Honig B; Couvillon A; Shymanets A; Nürnberg B; Asara JM; Parsons R
    J Biol Chem; 2015 Nov; 290(48):28915-31. PubMed ID: 26438819
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells.
    Lucato CM; Halls ML; Ooms LM; Liu HJ; Mitchell CA; Whisstock JC; Ellisdon AM
    J Biol Chem; 2015 Aug; 290(34):20827-20840. PubMed ID: 26112412
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PREX1 integrates G protein-coupled receptor and phosphoinositide 3-kinase signaling to promote glioblastoma invasion.
    Gont A; Daneshmand M; Woulfe J; Lavictoire SJ; Lorimer IA
    Oncotarget; 2017 Jan; 8(5):8559-8573. PubMed ID: 28051998
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PtdIns(3,4,5)P3-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling.
    Liu HJ; Ooms LM; Srijakotre N; Man J; Vieusseux J; Waters JE; Feng Y; Bailey CG; Rasko JE; Price JT; Mitchell CA
    J Biol Chem; 2016 Aug; 291(33):17258-70. PubMed ID: 27358402
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation.
    Aslan JE; Baker SM; Loren CP; Haley KM; Itakura A; Pang J; Greenberg DL; David LL; Manser E; Chernoff J; McCarty OJ
    Am J Physiol Cell Physiol; 2013 Sep; 305(5):C519-28. PubMed ID: 23784547
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphatidylinositol-3,4,5-triphosphate-dependent Rac exchange factor 1 regulates epinephrine-induced exocytosis of Weibel-Palade bodies.
    van Hooren KW; van Breevoort D; Fernandez-Borja M; Meijer AB; Eikenboom J; Bierings R; Voorberg J
    J Thromb Haemost; 2014 Feb; 12(2):273-81. PubMed ID: 24283667
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1.
    Pan D; Barber MA; Hornigold K; Baker MJ; Toth JM; Oxley D; Welch HC
    J Biol Chem; 2016 Mar; 291(12):6359-75. PubMed ID: 26792863
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gβγ signaling to the chemotactic effector P-REX1 and mammalian cell migration is directly regulated by Gα
    Cervantes-Villagrana RD; Adame-García SR; García-Jiménez I; Color-Aparicio VM; Beltrán-Navarro YM; König GM; Kostenis E; Reyes-Cruz G; Gutkind JS; Vázquez-Prado J
    J Biol Chem; 2019 Jan; 294(2):531-546. PubMed ID: 30446620
    [TBL] [Abstract][Full Text] [Related]  

  • 10. GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation that drives PI3Kγ/PREX1 signaling and T cell cytokine secretion.
    Dinkel BA; Kremer KN; Rollins MR; Medlyn MJ; Hedin KE
    J Biol Chem; 2018 Sep; 293(36):14022-14039. PubMed ID: 30018141
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphorylation of P-Rex1 by the cyclic AMP-dependent protein kinase inhibits the phosphatidylinositiol (3,4,5)-trisphosphate and Gbetagamma-mediated regulation of its activity.
    Mayeenuddin LH; Garrison JC
    J Biol Chem; 2006 Jan; 281(4):1921-8. PubMed ID: 16301320
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of ephexin1, a guanine nucleotide exchange factor of Rho family GTPases, by fibroblast growth factor receptor-mediated tyrosine phosphorylation.
    Zhang Y; Sawada T; Jing X; Yokote H; Yan X; Sakaguchi K
    J Biol Chem; 2007 Oct; 282(42):31103-12. PubMed ID: 17702745
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction of lamellipodia by Kalirin does not require its guanine nucleotide exchange factor activity.
    Schiller MR; Blangy A; Huang J; Mains RE; Eipper BA
    Exp Cell Res; 2005 Jul; 307(2):402-17. PubMed ID: 15950621
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of Rac guanine nucleotide exchange factors promoting Lgl1 phosphorylation in glioblastoma.
    Lavictoire SJ; Jomaa D; Gont A; Jardine K; Cook DP; Lorimer IAJ
    J Biol Chem; 2021 Nov; 297(5):101172. PubMed ID: 34624316
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade.
    Baird D; Feng Q; Cerione RA
    Curr Biol; 2005 Jan; 15(1):1-10. PubMed ID: 15649357
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insulin activates a p21-activated kinase in muscle cells via phosphatidylinositol 3-kinase.
    Tsakiridis T; Taha C; Grinstein S; Klip A
    J Biol Chem; 1996 Aug; 271(33):19664-7. PubMed ID: 8702668
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways.
    Lim L; Manser E; Leung T; Hall C
    Eur J Biochem; 1996 Dec; 242(2):171-85. PubMed ID: 8973630
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Kalirin, a GEF for Rac1, plays an important role in FSTL-1-mediated glucose uptake in skeletal muscle cells.
    Lee HJ; Lee JO; Lee YW; Kim SA; Park SH; Kim HS
    Cell Signal; 2017 Jan; 29():150-157. PubMed ID: 27989699
    [TBL] [Abstract][Full Text] [Related]  

  • 19. cAMP-dependent activation of the Rac guanine exchange factor P-REX1 by type I protein kinase A (PKA) regulatory subunits.
    Adame-García SR; Cervantes-Villagrana RD; Orduña-Castillo LB; Del Rio JC; Gutkind JS; Reyes-Cruz G; Taylor SS; Vázquez-Prado J
    J Biol Chem; 2019 Feb; 294(7):2232-2246. PubMed ID: 30530493
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Endogenous RhoG is rapidly activated after epidermal growth factor stimulation through multiple guanine-nucleotide exchange factors.
    Samson T; Welch C; Monaghan-Benson E; Hahn KM; Burridge K
    Mol Biol Cell; 2010 May; 21(9):1629-42. PubMed ID: 20237158
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.