113 related articles for article (PubMed ID: 27485195)
1. Pharmacophore Model Refinement for 11β-Hydroxysteroid Dehydrogenase Inhibitors: Search for Modulators of Intracellular Glucocorticoid Concentrations.
Vuorinen A; Nashev LG; Odermatt A; Rollinger JM; Schuster D
Mol Inform; 2014 Jan; 33(1):15-25. PubMed ID: 27485195
[TBL] [Abstract][Full Text] [Related]
2. The discovery of new 11beta-hydroxysteroid dehydrogenase type 1 inhibitors by common feature pharmacophore modeling and virtual screening.
Schuster D; Maurer EM; Laggner C; Nashev LG; Wilckens T; Langer T; Odermatt A
J Med Chem; 2006 Jun; 49(12):3454-66. PubMed ID: 16759088
[TBL] [Abstract][Full Text] [Related]
3. Identification of novel 11β-HSD1 inhibitors by combined ligand- and structure-based virtual screening.
Lagos CF; Vecchiola A; Allende F; Fuentes CA; Tichauer JE; Valdivia C; Solari S; Campino C; Tapia-Castillo A; Baudrand R; Villarroel P; Cifuentes M; Owen GI; Carvajal CA; Fardella CE
Mol Cell Endocrinol; 2014 Mar; 384(1-2):71-82. PubMed ID: 24447464
[TBL] [Abstract][Full Text] [Related]
4. Expression of 11β-hydroxysteroid dehydrogenase 1 and 2 in patients with chronic rhinosinusitis and their possible contribution to local glucocorticoid activation in sinus mucosa.
Jun YJ; Park SJ; Kim TH; Lee SH; Lee KJ; Hwang SM; Lee SH
J Allergy Clin Immunol; 2014 Oct; 134(4):926-934.e6. PubMed ID: 24810847
[TBL] [Abstract][Full Text] [Related]
5. Differential expression of 11β-hydroxysteroid dehydrogenase type 1 and 2 in mild and moderate/severe persistent allergic nasal mucosa and regulation of their expression by Th2 cytokines: asthma and rhinitis.
Jun YJ; Park SJ; Hwang JW; Kim TH; Jung KJ; Jung JY; Hwang GH; Lee SH; Lee SH
Clin Exp Allergy; 2014 Feb; 44(2):197-211. PubMed ID: 24447082
[TBL] [Abstract][Full Text] [Related]
6. Recent advances in the study of 11β-Hydroxysteroid dehydrogenase type 2 (11β-HSD2)Inhibitors.
Zhou C; Ye F; Wu H; Ye H; Chen Q
Environ Toxicol Pharmacol; 2017 Jun; 52():47-53. PubMed ID: 28366868
[TBL] [Abstract][Full Text] [Related]
7. Endogenous inhibitors (GALFs) of 11beta-hydroxysteroid dehydrogenase isoforms 1 and 2: derivatives of adrenally produced corticosterone and cortisol.
Morris DJ; Latif SA; Hardy MP; Brem AS
J Steroid Biochem Mol Biol; 2007 May; 104(3-5):161-8. PubMed ID: 17459698
[TBL] [Abstract][Full Text] [Related]
8. Expression profiles of cortisol-inactivating enzyme, 11β-hydroxysteroid dehydrogenase-2, in human epidermal tumors and its role in keratinocyte proliferation.
Terao M; Itoi S; Murota H; Katayama I
Exp Dermatol; 2013 Feb; 22(2):98-101. PubMed ID: 23362866
[TBL] [Abstract][Full Text] [Related]
9. Altered activity of 11beta-hydroxysteroid dehydrogenase types 1 and 2 in skeletal muscle confers metabolic protection in subjects with type 2 diabetes.
Jang C; Obeyesekere VR; Dilley RJ; Krozowski Z; Inder WJ; Alford FP
J Clin Endocrinol Metab; 2007 Aug; 92(8):3314-20. PubMed ID: 17519316
[TBL] [Abstract][Full Text] [Related]
10. 11beta-hydroxysteroid dehydrogenase type 1 inhibitors for metabolic syndrome.
Schnackenberg CG
Curr Opin Investig Drugs; 2008 Mar; 9(3):295-300. PubMed ID: 18311666
[TBL] [Abstract][Full Text] [Related]
11. Prereceptor regulation of glucocorticoid action by 11beta-hydroxysteroid dehydrogenase: a novel determinant of cell proliferation.
Rabbitt EH; Lavery GG; Walker EA; Cooper MS; Stewart PM; Hewison M
FASEB J; 2002 Jan; 16(1):36-44. PubMed ID: 11772934
[TBL] [Abstract][Full Text] [Related]
12. Effect of hyperlipidemia on 11β-hydroxysteroid-dehydrogenase, glucocorticoid receptor, and leptin expression in insulin-sensitive tissues of cats.
Sieber-Ruckstuhl NS; Zini E; Osto M; Franchini M; Boretti FS; Meli ML; Sigrist B; Lutz TA; Reusch CE
Domest Anim Endocrinol; 2010 Nov; 39(4):222-30. PubMed ID: 20688460
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of 11β-hydroxysteroid dehydrogenase 2 by the fungicides itraconazole and posaconazole.
Beck KR; Bächler M; Vuorinen A; Wagner S; Akram M; Griesser U; Temml V; Klusonova P; Yamaguchi H; Schuster D; Odermatt A
Biochem Pharmacol; 2017 Apr; 130():93-103. PubMed ID: 28131847
[TBL] [Abstract][Full Text] [Related]
14. Characterization of activity and binding mode of glycyrrhetinic acid derivatives inhibiting 11β-hydroxysteroid dehydrogenase type 2.
Kratschmar DV; Vuorinen A; Da Cunha T; Wolber G; Classen-Houben D; Doblhoff O; Schuster D; Odermatt A
J Steroid Biochem Mol Biol; 2011 May; 125(1-2):129-42. PubMed ID: 21236343
[TBL] [Abstract][Full Text] [Related]
15. Expression of 11β-hydroxysteroid dehydrogenase enzymes in human osteosarcoma: potential role in pathogenesis and as targets for treatments.
Patel P; Hardy R; Sumathi V; Bartle G; Kindblom LG; Grimer R; Bujalska I; Stewart PM; Rabbitt E; Gittoes NJ; Cooper MS
Endocr Relat Cancer; 2012 Aug; 19(4):589-98. PubMed ID: 22719058
[TBL] [Abstract][Full Text] [Related]
16. 11{beta}-Hydroxysteroid dehydrogenase 2 in rat leydig cells: its role in blunting glucocorticoid action at physiological levels of substrate.
Ge RS; Dong Q; Niu EM; Sottas CM; Hardy DO; Catterall JF; Latif SA; Morris DJ; Hardy MP
Endocrinology; 2005 Jun; 146(6):2657-64. PubMed ID: 15761036
[TBL] [Abstract][Full Text] [Related]
17. In vivo evaluation of 11beta-hydroxysteroid dehydrogenase activity in the rabbit eye.
Anderson S; Carreiro S; Quenzer T; Gale D; Xiang C; Gukasyan H; Lafontaine J; Cheng H; Krauss A; Prasanna G
J Ocul Pharmacol Ther; 2009 Jun; 25(3):215-22. PubMed ID: 19456256
[TBL] [Abstract][Full Text] [Related]
18. Structure-based virtual screening for identification of novel 11beta-HSD1 inhibitors.
Yang H; Shen Y; Chen J; Jiang Q; Leng Y; Shen J
Eur J Med Chem; 2009 Mar; 44(3):1167-71. PubMed ID: 18653260
[TBL] [Abstract][Full Text] [Related]
19. Virtual screening as a strategy for the identification of xenobiotics disrupting corticosteroid action.
Nashev LG; Vuorinen A; Praxmarer L; Chantong B; Cereghetti D; Winiger R; Schuster D; Odermatt A
PLoS One; 2012; 7(10):e46958. PubMed ID: 23056542
[TBL] [Abstract][Full Text] [Related]
20. Modulation of 11beta-hydroxysteroid dehydrogenase isozymes by proinflammatory cytokines in osteoblasts: an autocrine switch from glucocorticoid inactivation to activation.
Cooper MS; Bujalska I; Rabbitt E; Walker EA; Bland R; Sheppard MC; Hewison M; Stewart PM
J Bone Miner Res; 2001 Jun; 16(6):1037-44. PubMed ID: 11393780
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
