These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Icariin enhances cytotoxicity of doxorubicin in human multidrug-resistant osteosarcoma cells by inhibition of ABCB1 and down-regulation of the PI3K/Akt pathway. Wang Z; Yang L; Xia Y; Guo C; Kong L Biol Pharm Bull; 2015; 38(2):277-84. PubMed ID: 25747987 [TBL] [Abstract][Full Text] [Related]
5. Pioglitazone, an agonist of PPARγ, reverses doxorubicin-resistance in an osteosarcoma patient-derived orthotopic xenograft model by downregulating P-glycoprotein expression. Higuchi T; Sugisawa N; Miyake K; Oshiro H; Yamamoto N; Hayashi K; Kimura H; Miwa S; Igarashi K; Kline Z; Bouvet M; Singh SR; Tsuchiya H; Hoffman RM Biomed Pharmacother; 2019 Oct; 118():109356. PubMed ID: 31545293 [TBL] [Abstract][Full Text] [Related]
6. Nelfinavir targets multiple drug resistance mechanisms to increase the efficacy of doxorubicin in MCF-7/Dox breast cancer cells. Chakravarty G; Mathur A; Mallade P; Gerlach S; Willis J; Datta A; Srivastav S; Abdel-Mageed AB; Mondal D Biochimie; 2016 May; 124():53-64. PubMed ID: 26844637 [TBL] [Abstract][Full Text] [Related]
7. Polydatin inhibits proliferation and promotes apoptosis of doxorubicin-resistant osteosarcoma through LncRNA TUG1 mediated suppression of Akt signaling. Hu T; Fei Z; Su H; Xie R; Chen L Toxicol Appl Pharmacol; 2019 May; 371():55-62. PubMed ID: 30974157 [TBL] [Abstract][Full Text] [Related]
8. GRP78 inhibition enhances ATF4-induced cell death by the deubiquitination and stabilization of CHOP in human osteosarcoma. Luo J; Xia Y; Luo J; Li J; Zhang C; Zhang H; Ma T; Yang L; Kong L Cancer Lett; 2017 Dec; 410():112-123. PubMed ID: 28947141 [TBL] [Abstract][Full Text] [Related]
9. Long non-coding RNA CTA sensitizes osteosarcoma cells to doxorubicin through inhibition of autophagy. Wang Z; Liu Z; Wu S Oncotarget; 2017 May; 8(19):31465-31477. PubMed ID: 28415557 [TBL] [Abstract][Full Text] [Related]
10. ABCB1-overexpressing MG63/DOX cell xenograft model: maintain the MDR phenotype in vivo. Zhou Z; Wan L; Han Y; Meng X; Yang Q; Li Y; Yu Q; Shen Z; Guo C Pharm Biol; 2013 Aug; 51(8):968-73. PubMed ID: 23735077 [TBL] [Abstract][Full Text] [Related]
11. MK2206 overcomes the resistance of human liver cancer stem cells to sorafenib by inhibition of pAkt and upregulation of pERK. Zhai B; Zhang X; Sun B; Cao L; Zhao L; Li J; Ge N; Chen L; Qian H; Yin Z Tumour Biol; 2016 Jun; 37(6):8047-55. PubMed ID: 26711788 [TBL] [Abstract][Full Text] [Related]
12. P-Glycoprotein Overexpression Is Associated With Cisplatin Resistance in Human Osteosarcoma. He C; Sun Z; Hoffman RM; Yang Z; Jiang Y; Wang L; Hao Y Anticancer Res; 2019 Apr; 39(4):1711-1718. PubMed ID: 30952710 [TBL] [Abstract][Full Text] [Related]
13. Targeting ABCB1 (MDR1) in multi-drug resistant osteosarcoma cells using the CRISPR-Cas9 system to reverse drug resistance. Liu T; Li Z; Zhang Q; De Amorim Bernstein K; Lozano-Calderon S; Choy E; Hornicek FJ; Duan Z Oncotarget; 2016 Dec; 7(50):83502-83513. PubMed ID: 27835872 [TBL] [Abstract][Full Text] [Related]
14. Pioglitazone modulates doxorubicin resistance in a in vivo model of drug resistant osteosarcoma xenograft. Natarajan A; Ramachandran B; Gopisetty G; Jayavelu S; Sundersingh S; Rajkumar T Naunyn Schmiedebergs Arch Pharmacol; 2021 Feb; 394(2):361-371. PubMed ID: 33015747 [TBL] [Abstract][Full Text] [Related]
15. Targeted inhibition of T-cell factor activity promotes syndecan-2 expression and sensitization to doxorubicin in osteosarcoma cells and bone tumors in mice. Dieudonné FX; Marion A; Marie PJ; Modrowski D J Bone Miner Res; 2012 Oct; 27(10):2118-29. PubMed ID: 22550000 [TBL] [Abstract][Full Text] [Related]
16. Mesenchymal stem cells promote osteosarcoma cell survival and drug resistance through activation of STAT3. Tu B; Zhu J; Liu S; Wang L; Fan Q; Hao Y; Fan C; Tang TT Oncotarget; 2016 Jul; 7(30):48296-48308. PubMed ID: 27340780 [TBL] [Abstract][Full Text] [Related]
17. Combination treatment with MEK and AKT inhibitors is more effective than each drug alone in human non-small cell lung cancer in vitro and in vivo. Meng J; Dai B; Fang B; Bekele BN; Bornmann WG; Sun D; Peng Z; Herbst RS; Papadimitrakopoulou V; Minna JD; Peyton M; Roth JA PLoS One; 2010 Nov; 5(11):e14124. PubMed ID: 21124782 [TBL] [Abstract][Full Text] [Related]
18. Green tea catechins augment the antitumor activity of doxorubicin in an in vivo mouse model for chemoresistant liver cancer. Liang G; Tang A; Lin X; Li L; Zhang S; Huang Z; Tang H; Li QQ Int J Oncol; 2010 Jul; 37(1):111-23. PubMed ID: 20514403 [TBL] [Abstract][Full Text] [Related]
19. MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancer. Zhang Y; Talmon G; Wang J Cell Death Dis; 2015 Aug; 6(8):e1845. PubMed ID: 26247730 [TBL] [Abstract][Full Text] [Related]
20. Notch pathway inhibition using DAPT, a γ-secretase inhibitor (GSI), enhances the antitumor effect of cisplatin in resistant osteosarcoma. Dai G; Deng S; Guo W; Yu L; Yang J; Zhou S; Gao T Mol Carcinog; 2019 Jan; 58(1):3-18. PubMed ID: 29964327 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]