These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
474 related articles for article (PubMed ID: 27488531)
1. An In Vivo Reporter to Quantitatively and Temporally Analyze the Effects of CDK4/6 Inhibitor-Based Therapies in Melanoma. Teh JL; Purwin TJ; Greenawalt EJ; Chervoneva I; Goldberg A; Davies MA; Aplin AE Cancer Res; 2016 Sep; 76(18):5455-66. PubMed ID: 27488531 [TBL] [Abstract][Full Text] [Related]
2. Palbociclib synergizes with BRAF and MEK inhibitors in treatment naïve melanoma but not after the development of BRAF inhibitor resistance. Martin CA; Cullinane C; Kirby L; Abuhammad S; Lelliott EJ; Waldeck K; Young RJ; Brajanovski N; Cameron DP; Walker R; Sanij E; Poortinga G; Hannan RD; Pearson RB; Hicks RJ; McArthur GA; Sheppard KE Int J Cancer; 2018 May; 142(10):2139-2152. PubMed ID: 29243224 [TBL] [Abstract][Full Text] [Related]
3. Efficacy of the combination of MEK and CDK4/6 inhibitors in vitro and in vivo in KRAS mutant colorectal cancer models. Lee MS; Helms TL; Feng N; Gay J; Chang QE; Tian F; Wu JY; Toniatti C; Heffernan TP; Powis G; Kwong LN; Kopetz S Oncotarget; 2016 Jun; 7(26):39595-39608. PubMed ID: 27167191 [TBL] [Abstract][Full Text] [Related]
4. Preclinical development of G1T38: A novel, potent and selective inhibitor of cyclin dependent kinases 4/6 for use as an oral antineoplastic in patients with CDK4/6 sensitive tumors. Bisi JE; Sorrentino JA; Jordan JL; Darr DD; Roberts PJ; Tavares FX; Strum JC Oncotarget; 2017 Jun; 8(26):42343-42358. PubMed ID: 28418845 [TBL] [Abstract][Full Text] [Related]
5. Induction of Therapeutic Senescence in Vemurafenib-Resistant Melanoma by Extended Inhibition of CDK4/6. Yoshida A; Lee EK; Diehl JA Cancer Res; 2016 May; 76(10):2990-3002. PubMed ID: 26988987 [TBL] [Abstract][Full Text] [Related]
6. Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor-Resistant Melanoma. Nassar KW; Hintzsche JD; Bagby SM; Espinoza V; Langouët-Astrié C; Amato CM; Chimed TS; Fujita M; Robinson W; Tan AC; Schweppe RE Mol Cancer Ther; 2021 Oct; 20(10):2049-2060. PubMed ID: 34376578 [TBL] [Abstract][Full Text] [Related]
8. Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma. AbuHammad S; Cullinane C; Martin C; Bacolas Z; Ward T; Chen H; Slater A; Ardley K; Kirby L; Chan KT; Brajanovski N; Smith LK; Rao AD; Lelliott EJ; Kleinschmidt M; Vergara IA; Papenfuss AT; Lau P; Ghosh P; Haupt S; Haupt Y; Sanij E; Poortinga G; Pearson RB; Falk H; Curtis DJ; Stupple P; Devlin M; Street I; Davies MA; McArthur GA; Sheppard KE Proc Natl Acad Sci U S A; 2019 Sep; 116(36):17990-18000. PubMed ID: 31439820 [TBL] [Abstract][Full Text] [Related]
9. Metabolic Adaptations to MEK and CDK4/6 Cotargeting in Uveal Melanoma. Teh JLF; Purwin TJ; Han A; Chua V; Patel P; Baqai U; Liao C; Bechtel N; Sato T; Davies MA; Aguirre-Ghiso J; Aplin AE Mol Cancer Ther; 2020 Aug; 19(8):1719-1726. PubMed ID: 32430489 [TBL] [Abstract][Full Text] [Related]
10. Targeting CDK4/6 in patients with cancer. Hamilton E; Infante JR Cancer Treat Rev; 2016 Apr; 45():129-38. PubMed ID: 27017286 [TBL] [Abstract][Full Text] [Related]
11. Functional Determinants of Cell Cycle Plasticity and Sensitivity to CDK4/6 Inhibition. Kumarasamy V; Vail P; Nambiar R; Witkiewicz AK; Knudsen ES Cancer Res; 2021 Mar; 81(5):1347-1360. PubMed ID: 33323381 [TBL] [Abstract][Full Text] [Related]
12. Brain Exposure of Two Selective Dual CDK4 and CDK6 Inhibitors and the Antitumor Activity of CDK4 and CDK6 Inhibition in Combination with Temozolomide in an Intracranial Glioblastoma Xenograft. Raub TJ; Wishart GN; Kulanthaivel P; Staton BA; Ajamie RT; Sawada GA; Gelbert LM; Shannon HE; Sanchez-Martinez C; De Dios A Drug Metab Dispos; 2015 Sep; 43(9):1360-71. PubMed ID: 26149830 [TBL] [Abstract][Full Text] [Related]
13. Synthesis and Biological Evaluation of Novel Song X; Gan Q; Zhang X; Zhang J Mol Pharm; 2019 Oct; 16(10):4213-4222. PubMed ID: 31424939 [TBL] [Abstract][Full Text] [Related]
14. Oncogenic BRAF fusions in mucosal melanomas activate the MAPK pathway and are sensitive to MEK/PI3K inhibition or MEK/CDK4/6 inhibition. Kim HS; Jung M; Kang HN; Kim H; Park CW; Kim SM; Shin SJ; Kim SH; Kim SG; Kim EK; Yun MR; Zheng Z; Chung KY; Greenbowe J; Ali SM; Kim TM; Cho BC Oncogene; 2017 Jun; 36(23):3334-3345. PubMed ID: 28092667 [TBL] [Abstract][Full Text] [Related]
15. Biological specificity of CDK4/6 inhibitors: dose response relationship, in vivo signaling, and composite response signature. Knudsen ES; Hutcheson J; Vail P; Witkiewicz AK Oncotarget; 2017 Jul; 8(27):43678-43691. PubMed ID: 28620137 [TBL] [Abstract][Full Text] [Related]
16. CDK4/6 inhibitor palbociclib enhances the effect of pyrotinib in HER2-positive breast cancer. Zhang K; Hong R; Kaping L; Xu F; Xia W; Qin G; Zheng Q; Lu Q; Zhai Q; Shi Y; Yuan Z; Deng W; Chen M; Wang S Cancer Lett; 2019 Apr; 447():130-140. PubMed ID: 30677445 [TBL] [Abstract][Full Text] [Related]
17. MAPK Reliance via Acquired CDK4/6 Inhibitor Resistance in Cancer. de Leeuw R; McNair C; Schiewer MJ; Neupane NP; Brand LJ; Augello MA; Li Z; Cheng LC; Yoshida A; Courtney SM; Hazard ES; Hardiman G; Hussain MH; Diehl JA; Drake JM; Kelly WK; Knudsen KE Clin Cancer Res; 2018 Sep; 24(17):4201-4214. PubMed ID: 29739788 [No Abstract] [Full Text] [Related]
18. CDK4/6 blockade in breast cancer: current experience and future perspectives. Zardavas D; Pondé N; Tryfonidis K Expert Opin Investig Drugs; 2017 Dec; 26(12):1357-1372. PubMed ID: 29027483 [TBL] [Abstract][Full Text] [Related]
19. Chemoproteomic Evaluation of Target Engagement by the Cyclin-Dependent Kinase 4 and 6 Inhibitor Palbociclib Correlates with Cancer Cell Response. Nomanbhoy TK; Sharma G; Brown H; Wu J; Aban A; Vogeti S; Alemayehu S; Sykes M; Rosenblum JS; Kozarich JW Biochemistry; 2016 Sep; 55(38):5434-41. PubMed ID: 27571378 [TBL] [Abstract][Full Text] [Related]
20. Single-Cell Dynamics Determines Response to CDK4/6 Inhibition in Triple-Negative Breast Cancer. Asghar US; Barr AR; Cutts R; Beaney M; Babina I; Sampath D; Giltnane J; Lacap JA; Crocker L; Young A; Pearson A; Herrera-Abreu MT; Bakal C; Turner NC Clin Cancer Res; 2017 Sep; 23(18):5561-5572. PubMed ID: 28606920 [No Abstract] [Full Text] [Related] [Next] [New Search]