564 related articles for article (PubMed ID: 27493206)
1. Structure of the Tuberous Sclerosis Complex 2 (TSC2) N Terminus Provides Insight into Complex Assembly and Tuberous Sclerosis Pathogenesis.
Zech R; Kiontke S; Mueller U; Oeckinghaus A; Kümmel D
J Biol Chem; 2016 Sep; 291(38):20008-20. PubMed ID: 27493206
[TBL] [Abstract][Full Text] [Related]
2. Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb.
Tee AR; Manning BD; Roux PP; Cantley LC; Blenis J
Curr Biol; 2003 Aug; 13(15):1259-68. PubMed ID: 12906785
[TBL] [Abstract][Full Text] [Related]
3. Non-canonical functions of the tuberous sclerosis complex-Rheb signalling axis.
Neuman NA; Henske EP
EMBO Mol Med; 2011 Apr; 3(4):189-200. PubMed ID: 21412983
[TBL] [Abstract][Full Text] [Related]
4. Activation of Rheb, but not of mTORC1, impairs spine synapse morphogenesis in tuberous sclerosis complex.
Yasuda S; Sugiura H; Katsurabayashi S; Shimada T; Tanaka H; Takasaki K; Iwasaki K; Kobayashi T; Hino O; Yamagata K
Sci Rep; 2014 Jun; 4():5155. PubMed ID: 24889507
[TBL] [Abstract][Full Text] [Related]
5. TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1.
Dibble CC; Elis W; Menon S; Qin W; Klekota J; Asara JM; Finan PM; Kwiatkowski DJ; Murphy LO; Manning BD
Mol Cell; 2012 Aug; 47(4):535-46. PubMed ID: 22795129
[TBL] [Abstract][Full Text] [Related]
6. The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis.
Kang YJ; Lu MK; Guan KL
Cell Death Differ; 2011 Jan; 18(1):133-44. PubMed ID: 20616807
[TBL] [Abstract][Full Text] [Related]
7. The TSC1-TSC2 complex: a molecular switchboard controlling cell growth.
Huang J; Manning BD
Biochem J; 2008 Jun; 412(2):179-90. PubMed ID: 18466115
[TBL] [Abstract][Full Text] [Related]
8. Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway.
Yoshida S; Hong S; Suzuki T; Nada S; Mannan AM; Wang J; Okada M; Guan KL; Inoki K
J Biol Chem; 2011 Sep; 286(37):32651-60. PubMed ID: 21784859
[TBL] [Abstract][Full Text] [Related]
9. Mourning Dr. Alfred G. Knudson: the two-hit hypothesis, tumor suppressor genes, and the tuberous sclerosis complex.
Hino O; Kobayashi T
Cancer Sci; 2017 Jan; 108(1):5-11. PubMed ID: 27862655
[TBL] [Abstract][Full Text] [Related]
10. Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway.
Lin Y; Henderson P; Pettersson S; Satsangi J; Hupp T; Stevens C
FEBS J; 2011 Jan; 278(2):354-70. PubMed ID: 21134130
[TBL] [Abstract][Full Text] [Related]
11. Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity.
Li Y; Inoki K; Guan KL
Mol Cell Biol; 2004 Sep; 24(18):7965-75. PubMed ID: 15340059
[TBL] [Abstract][Full Text] [Related]
12. Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent.
Karbowniczek M; Cash T; Cheung M; Robertson GP; Astrinidis A; Henske EP
J Biol Chem; 2004 Jul; 279(29):29930-7. PubMed ID: 15150271
[TBL] [Abstract][Full Text] [Related]
13. Rhebbing up mTOR: new insights on TSC1 and TSC2, and the pathogenesis of tuberous sclerosis.
Kwiatkowski DJ
Cancer Biol Ther; 2003; 2(5):471-6. PubMed ID: 14614311
[TBL] [Abstract][Full Text] [Related]
14. Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity.
Carroll B; Maetzel D; Maddocks OD; Otten G; Ratcliff M; Smith GR; Dunlop EA; Passos JF; Davies OR; Jaenisch R; Tee AR; Sarkar S; Korolchuk VI
Elife; 2016 Jan; 5():. PubMed ID: 26742086
[TBL] [Abstract][Full Text] [Related]
15. Tuberous sclerosis complex: from Drosophila to human disease.
Pan D; Dong J; Zhang Y; Gao X
Trends Cell Biol; 2004 Feb; 14(2):78-85. PubMed ID: 15102439
[TBL] [Abstract][Full Text] [Related]
16. MCRS1 binds and couples Rheb to amino acid-dependent mTORC1 activation.
Fawal MA; Brandt M; Djouder N
Dev Cell; 2015 Apr; 33(1):67-81. PubMed ID: 25816988
[TBL] [Abstract][Full Text] [Related]
17. Structural basis for the unique biological function of small GTPase RHEB.
Yu Y; Li S; Xu X; Li Y; Guan K; Arnold E; Ding J
J Biol Chem; 2005 Apr; 280(17):17093-100. PubMed ID: 15728574
[TBL] [Abstract][Full Text] [Related]
18. Rapamycin-insensitive up-regulation of MMP2 and other genes in tuberous sclerosis complex 2-deficient lymphangioleiomyomatosis-like cells.
Lee PS; Tsang SW; Moses MA; Trayes-Gibson Z; Hsiao LL; Jensen R; Squillace R; Kwiatkowski DJ
Am J Respir Cell Mol Biol; 2010 Feb; 42(2):227-34. PubMed ID: 19395678
[TBL] [Abstract][Full Text] [Related]
19. Ral and Rheb GTPase activating proteins integrate mTOR and GTPase signaling in aging, autophagy, and tumor cell invasion.
Martin TD; Chen XW; Kaplan RE; Saltiel AR; Walker CL; Reiner DJ; Der CJ
Mol Cell; 2014 Jan; 53(2):209-20. PubMed ID: 24389102
[TBL] [Abstract][Full Text] [Related]
20. Rheb fills a GAP between TSC and TOR.
Manning BD; Cantley LC
Trends Biochem Sci; 2003 Nov; 28(11):573-6. PubMed ID: 14607085
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
