These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 27493538)

  • 1. Mechanism of the nucleotidyl-transfer reaction in DNA polymerase revealed by time-resolved protein crystallography.
    Nakamura T; Zhao Y; Yamagata Y; Hua YJ; Yang W
    Biophysics (Nagoya-shi); 2013; 9():31-6. PubMed ID: 27493538
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Watching DNA polymerase η make a phosphodiester bond.
    Nakamura T; Zhao Y; Yamagata Y; Hua YJ; Yang W
    Nature; 2012 Jul; 487(7406):196-201. PubMed ID: 22785315
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase η and reduces DNA synthesis fidelity.
    Chang C; Lee Luo C; Eleraky S; Lin A; Zhou G; Gao Y
    J Biol Chem; 2023 Mar; 299(3):102938. PubMed ID: 36702254
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta.
    Pelletier H; Sawaya MR; Wolfle W; Wilson SH; Kraut J
    Biochemistry; 1996 Oct; 35(39):12762-77. PubMed ID: 8841119
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
    Chang C; Lee Luo C; Gao Y
    Nat Commun; 2022 Apr; 13(1):2346. PubMed ID: 35487947
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Polymerase-tailored variations in the water-mediated and substrate-assisted mechanism for nucleotidyl transfer: insights from a study of T7 DNA polymerase.
    Wang L; Broyde S; Zhang Y
    J Mol Biol; 2009 Jun; 389(4):787-96. PubMed ID: 19389406
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases.
    Castro C; Smidansky E; Maksimchuk KR; Arnold JJ; Korneeva VS; Götte M; Konigsberg W; Cameron CE
    Proc Natl Acad Sci U S A; 2007 Mar; 104(11):4267-72. PubMed ID: 17360513
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A quantum mechanical investigation of possible mechanisms for the nucleotidyl transfer reaction catalyzed by DNA polymerase beta.
    Bojin MD; Schlick T
    J Phys Chem B; 2007 Sep; 111(38):11244-52. PubMed ID: 17764165
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
    Gregory MT; Gao Y; Cui Q; Yang W
    Proc Natl Acad Sci U S A; 2021 Jun; 118(23):. PubMed ID: 34088846
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A water-mediated and substrate-assisted catalytic mechanism for Sulfolobus solfataricus DNA polymerase IV.
    Wang L; Yu X; Hu P; Broyde S; Zhang Y
    J Am Chem Soc; 2007 Apr; 129(15):4731-7. PubMed ID: 17375926
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dynamic structures of horse liver alcohol dehydrogenase (HLADH): results of molecular dynamics simulations of HLADH-NAD(+)-PhCH(2)OH, HLADH-NAD(+)-PhCH(2)O(-), and HLADH-NADH-PhCHO.
    Luo J; Bruice TC
    J Am Chem Soc; 2001 Dec; 123(48):11952-9. PubMed ID: 11724603
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP.
    Pelletier H; Sawaya MR; Kumar A; Wilson SH; Kraut J
    Science; 1994 Jun; 264(5167):1891-903. PubMed ID: 7516580
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Conformational properties of dinucleoside monophosphates in solution: dipurines and dipyrimidines.
    Lee CH; Ezra FS; Kondo NS; Sarma RH; Danyluk SS
    Biochemistry; 1976 Aug; 15(16):3627-39. PubMed ID: 952881
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nucleic acid polymerases use a general acid for nucleotidyl transfer.
    Castro C; Smidansky ED; Arnold JJ; Maksimchuk KR; Moustafa I; Uchida A; Götte M; Konigsberg W; Cameron CE
    Nat Struct Mol Biol; 2009 Feb; 16(2):212-8. PubMed ID: 19151724
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The effects of monovalent cations Li+, Na+, K+, NH4+, Rb+ and Cs+ on the solid and solution structures of the nucleic acid components. Metal ion binding and sugar conformation.
    Tajmir-Riahi HA; Messaoudi S
    J Biomol Struct Dyn; 1992 Oct; 10(2):345-65. PubMed ID: 1334674
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The C2'- and C3'-endo equilibrium for AMP molecules bound in the cystathionine-beta-synthase domain.
    Feng N; Qi C; Hou YJ; Zhang Y; Wang DC; Li DF
    Biochem Biophys Res Commun; 2018 Mar; 497(2):646-651. PubMed ID: 29453981
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structures of intermediates along the catalytic cycle of terminal deoxynucleotidyltransferase: dynamical aspects of the two-metal ion mechanism.
    Gouge J; Rosario S; Romain F; Beguin P; Delarue M
    J Mol Biol; 2013 Nov; 425(22):4334-52. PubMed ID: 23856622
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Detection of Reaction Intermediates in Mg
    Samara NL; Gao Y; Wu J; Yang W
    Methods Enzymol; 2017; 592():283-327. PubMed ID: 28668125
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Exploring the Role of the Third Active Site Metal Ion in DNA Polymerase η with QM/MM Free Energy Simulations.
    Stevens DR; Hammes-Schiffer S
    J Am Chem Soc; 2018 Jul; 140(28):8965-8969. PubMed ID: 29932331
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An equivalent metal ion in one- and two-metal-ion catalysis.
    Yang W
    Nat Struct Mol Biol; 2008 Nov; 15(11):1228-31. PubMed ID: 18953336
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.