BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 27494936)

  • 1. An LPL-specific monoclonal antibody, 88B8, that abolishes the binding of LPL to GPIHBP1.
    Allan CM; Larsson M; Hu X; He C; Jung RS; Mapar A; Voss C; Miyashita K; Machida T; Murakami M; Nakajima K; Bensadoun A; Ploug M; Fong LG; Young SG; Beigneux AP
    J Lipid Res; 2016 Oct; 57(10):1889-1898. PubMed ID: 27494936
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutations in lipoprotein lipase that block binding to the endothelial cell transporter GPIHBP1.
    Voss CV; Davies BS; Tat S; Gin P; Fong LG; Pelletier C; Mottler CD; Bensadoun A; Beigneux AP; Young SG
    Proc Natl Acad Sci U S A; 2011 May; 108(19):7980-4. PubMed ID: 21518912
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chylomicronemia mutations yield new insights into interactions between lipoprotein lipase and GPIHBP1.
    Gin P; Goulbourne CN; Adeyo O; Beigneux AP; Davies BS; Tat S; Voss CV; Bensadoun A; Fong LG; Young SG
    Hum Mol Genet; 2012 Jul; 21(13):2961-72. PubMed ID: 22493000
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase.
    Kristensen KK; Midtgaard SR; Mysling S; Kovrov O; Hansen LB; Skar-Gislinge N; Beigneux AP; Kragelund BB; Olivecrona G; Young SG; Jørgensen TJD; Fong LG; Ploug M
    Proc Natl Acad Sci U S A; 2018 Jun; 115(26):E6020-E6029. PubMed ID: 29899144
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain.
    Mysling S; Kristensen KK; Larsson M; Beigneux AP; Gårdsvoll H; Fong LG; Bensadouen A; Jørgensen TJ; Young SG; Ploug M
    Elife; 2016 Jan; 5():e12095. PubMed ID: 26725083
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A protein of capillary endothelial cells, GPIHBP1, is crucial for plasma triglyceride metabolism.
    Young SG; Song W; Yang Y; Birrane G; Jiang H; Beigneux AP; Ploug M; Fong LG
    Proc Natl Acad Sci U S A; 2022 Sep; 119(36):e2211136119. PubMed ID: 36037340
    [TBL] [Abstract][Full Text] [Related]  

  • 7. GPIHBP1 missense mutations often cause multimerization of GPIHBP1 and thereby prevent lipoprotein lipase binding.
    Beigneux AP; Fong LG; Bensadoun A; Davies BS; Oberer M; Gårdsvoll H; Ploug M; Young SG
    Circ Res; 2015 Feb; 116(4):624-32. PubMed ID: 25387803
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A new monoclonal antibody, 4-1a, that binds to the amino terminus of human lipoprotein lipase.
    Bensadoun A; Mottler CD; Pelletier C; Wu D; Seo JJ; Leung CS; Adeyo O; Goulbourne CN; Gin P; Fong LG; Young SG; Beigneux AP
    Biochim Biophys Acta; 2014 Jul; 1841(7):970-6. PubMed ID: 24681165
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Highly conserved cysteines within the Ly6 domain of GPIHBP1 are crucial for the binding of lipoprotein lipase.
    Beigneux AP; Gin P; Davies BS; Weinstein MM; Bensadoun A; Fong LG; Young SG
    J Biol Chem; 2009 Oct; 284(44):30240-7. PubMed ID: 19726683
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The intrinsic instability of the hydrolase domain of lipoprotein lipase facilitates its inactivation by ANGPTL4-catalyzed unfolding.
    Leth-Espensen KZ; Kristensen KK; Kumari A; Winther AL; Young SG; Jørgensen TJD; Ploug M
    Proc Natl Acad Sci U S A; 2021 Mar; 118(12):. PubMed ID: 33723082
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The lipoprotein lipase that is shuttled into capillaries by GPIHBP1 enters the glycocalyx where it mediates lipoprotein processing.
    Song W; Beigneux AP; Weston TA; Chen K; Yang Y; Nguyen LP; Guagliardo P; Jung H; Tran AP; Tu Y; Tran C; Birrane G; Miyashita K; Nakajima K; Murakami M; Tontonoz P; Jiang H; Ploug M; Fong LG; Young SG
    Proc Natl Acad Sci U S A; 2023 Oct; 120(44):e2313825120. PubMed ID: 37871217
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Multimerization of glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) and familial chylomicronemia from a serine-to-cysteine substitution in GPIHBP1 Ly6 domain.
    Plengpanich W; Young SG; Khovidhunkit W; Bensadoun A; Karnman H; Ploug M; Gårdsvoll H; Leung CS; Adeyo O; Larsson M; Muanpetch S; Charoen S; Fong LG; Niramitmahapanya S; Beigneux AP
    J Biol Chem; 2014 Jul; 289(28):19491-9. PubMed ID: 24847059
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutating a conserved cysteine in GPIHBP1 reduces amounts of GPIHBP1 in capillaries and abolishes LPL binding.
    Allan CM; Jung CJ; Larsson M; Heizer PJ; Tu Y; Sandoval NP; Dang TLP; Jung RS; Beigneux AP; de Jong PJ; Fong LG; Young SG
    J Lipid Res; 2017 Jul; 58(7):1453-1461. PubMed ID: 28476858
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evidence for Two Distinct Binding Sites for Lipoprotein Lipase on Glycosylphosphatidylinositol-anchored High Density Lipoprotein-binding Protein 1 (GPIHBP1).
    Reimund M; Larsson M; Kovrov O; Kasvandik S; Olivecrona G; Lookene A
    J Biol Chem; 2015 May; 290(22):13919-34. PubMed ID: 25873395
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis.
    Birrane G; Beigneux AP; Dwyer B; Strack-Logue B; Kristensen KK; Francone OL; Fong LG; Mertens HDT; Pan CQ; Ploug M; Young SG; Meiyappan M
    Proc Natl Acad Sci U S A; 2019 Jan; 116(5):1723-1732. PubMed ID: 30559189
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Equivalent binding of wild-type lipoprotein lipase (LPL) and S447X-LPL to GPIHBP1, the endothelial cell LPL transporter.
    Turlo K; Leung CS; Seo JJ; Goulbourne CN; Adeyo O; Gin P; Voss C; Bensadoun A; Fong LG; Young SG; Beigneux AP
    Biochim Biophys Acta; 2014 Jul; 1841(7):963-9. PubMed ID: 24704550
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mobility of "HSPG-bound" LPL explains how LPL is able to reach GPIHBP1 on capillaries.
    Allan CM; Larsson M; Jung RS; Ploug M; Bensadoun A; Beigneux AP; Fong LG; Young SG
    J Lipid Res; 2017 Jan; 58(1):216-225. PubMed ID: 27811232
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Electrostatic sheathing of lipoprotein lipase is essential for its movement across capillary endothelial cells.
    Song W; Beigneux AP; Winther AL; Kristensen KK; Grønnemose AL; Yang Y; Tu Y; Munguia P; Morales J; Jung H; de Jong PJ; Jung CJ; Miyashita K; Kimura T; Nakajima K; Murakami M; Birrane G; Jiang H; Tontonoz P; Ploug M; Fong LG; Young SG
    J Clin Invest; 2022 Mar; 132(5):. PubMed ID: 35229724
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Angiopoietin-like 4 Modifies the Interactions between Lipoprotein Lipase and Its Endothelial Cell Transporter GPIHBP1.
    Chi X; Shetty SK; Shows HW; Hjelmaas AJ; Malcolm EK; Davies BS
    J Biol Chem; 2015 May; 290(19):11865-77. PubMed ID: 25809481
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Assessing the role of the glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) three-finger domain in binding lipoprotein lipase.
    Beigneux AP; Davies BS; Tat S; Chen J; Gin P; Voss CV; Weinstein MM; Bensadoun A; Pullinger CR; Fong LG; Young SG
    J Biol Chem; 2011 Jun; 286(22):19735-43. PubMed ID: 21478160
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.