BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 27495738)

  • 1. I86A/C295A mutant secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus has broadened substrate specificity for aryl ketones.
    Nealon CM; Welsh TP; Kim CS; Phillips RS
    Arch Biochem Biophys; 2016 Sep; 606():151-6. PubMed ID: 27495738
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Impact of Expanded Small Alkyl-Binding Pocket by Triple Point Mutations on Substrate Specificity of Thermoanaerobacter ethanolicus Secondary Alcohol Dehydrogenase.
    Dwamena A; Phillips R; Kim CS
    J Microbiol Biotechnol; 2019 Mar; 29(3):373-381. PubMed ID: 30609883
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutagenesis of Met-151 and Thr-153 to alanine in Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase changes substrate specificity for acetophenones.
    Nealon CM; Kim CS; Dwamena AK; Phillips RS
    Enzyme Microb Technol; 2017 Oct; 105():59-63. PubMed ID: 28756862
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutation of cysteine-295 to alanine in secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus affects the enantioselectivity and substrate specificity of ketone reductions.
    Heiss C; Laivenieks M; Zeikus JG; Phillips RS
    Bioorg Med Chem; 2001 Jul; 9(7):1659-66. PubMed ID: 11425565
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Asymmetric reduction and oxidation of aromatic ketones and alcohols using W110A secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus.
    Musa MM; Ziegelmann-Fjeld KI; Vieille C; Zeikus JG; Phillips RS
    J Org Chem; 2007 Jan; 72(1):30-4. PubMed ID: 17194078
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystallization and preliminary X-ray diffraction analysis of the Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase I86A mutant.
    Protsko C; Vieille C; Laivenieks M; Prasad L; Sanders DA; Delbaere LT
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2010 Jul; 66(Pt 7):831-3. PubMed ID: 20606285
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystallographic snapshots of ternary complexes of thermophilic secondary alcohol dehydrogenase from Thermoanaerobacter pseudoethanolicus reveal the dynamics of ligand exchange and the proton relay network.
    Dinh T; Rahn KT; Phillips RS
    Proteins; 2022 Aug; 90(8):1570-1583. PubMed ID: 35357038
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase mutant derivative highly active and stereoselective on phenylacetone and benzylacetone.
    Ziegelmann-Fjeld KI; Musa MM; Phillips RS; Zeikus JG; Vieille C
    Protein Eng Des Sel; 2007 Feb; 20(2):47-55. PubMed ID: 17283007
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutation of Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase at Trp-110 affects stereoselectivity of aromatic ketone reduction.
    Patel JM; Musa MM; Rodriguez L; Sutton DA; Popik VV; Phillips RS
    Org Biomol Chem; 2014 Aug; 12(31):5905-10. PubMed ID: 24984815
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of the cofactor binding sites on the activities of secondary alcohol dehydrogenase (SADH).
    Wang T; Chen X; Han J; Ma S; Wang J; Li X; Zhang H; Liu Z; Yang Y
    Int J Biol Macromol; 2016 Jul; 88():385-91. PubMed ID: 27016086
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Exploring the reversal of enantioselectivity on a zinc-dependent alcohol dehydrogenase.
    Maria-Solano MA; Romero-Rivera A; Osuna S
    Org Biomol Chem; 2017 May; 15(19):4122-4129. PubMed ID: 28436515
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Xerogel-encapsulated W110A secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus performs asymmetric reduction of hydrophobic ketones in organic solvents.
    Musa MM; Ziegelmann-Fjeld KI; Vieille C; Zeikus JG; Phillips RS
    Angew Chem Int Ed Engl; 2007; 46(17):3091-4. PubMed ID: 17361973
    [No Abstract]   [Full Text] [Related]  

  • 13. Activity and selectivity of W110A secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus in organic solvents and ionic liquids: mono- and biphasic media.
    Musa MM; Ziegelmann-Fjeld KI; Vieille C; Phillips RS
    Org Biomol Chem; 2008 Mar; 6(5):887-92. PubMed ID: 18292880
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Investigation of asymmetric alcohol dehydrogenase (ADH) reduction of acetophenone derivatives: effect of charge density.
    Naik HG; Yeniad B; Koning CE; Heise A
    Org Biomol Chem; 2012 Jul; 10(25):4961-7. PubMed ID: 22609978
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The stereospecificity of secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus is partially determined by active site water.
    Heiss C; Laivenieks M; Zeikus JG; Phillips RS
    J Am Chem Soc; 2001 Jan; 123(2):345-6. PubMed ID: 11456527
    [No Abstract]   [Full Text] [Related]  

  • 16. The aldehyde/alcohol dehydrogenase (AdhE) in relation to the ethanol formation in Thermoanaerobacter ethanolicus JW200.
    Peng H; Wu G; Shao W
    Anaerobe; 2008 Apr; 14(2):125-7. PubMed ID: 17981479
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Induced axial chirality in biocatalytic asymmetric ketone reduction.
    Agudo R; Roiban GD; Reetz MT
    J Am Chem Soc; 2013 Feb; 135(5):1665-8. PubMed ID: 23075382
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Racemization of enantiopure secondary alcohols by Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase.
    Musa MM; Phillips RS; Laivenieks M; Vieille C; Takahashi M; Hamdan SM
    Org Biomol Chem; 2013 May; 11(17):2911-5. PubMed ID: 23525226
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Purification and characterization of an anti-Prelog alcohol dehydrogenase from Oenococcus oeni that reduces 2-octanone to (R)-2-octanol.
    Meng F; Xu Y
    Biotechnol Lett; 2010 Apr; 32(4):533-7. PubMed ID: 20035369
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Highly enantioselective mutant carbonyl reductases created via structure-based site-saturation mutagenesis.
    Li H; Yang Y; Zhu D; Hua L; Kantardjieff K
    J Org Chem; 2010 Nov; 75(22):7559-64. PubMed ID: 20964397
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.