BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 27498028)

  • 1. Protein kinase C-δ inhibitor, Rottlerin inhibits growth and survival of mycobacteria exclusively through Shikimate kinase.
    Pandey S; Chatterjee A; Jaiswal S; Kumar S; Ramachandran R; Srivastava KK
    Biochem Biophys Res Commun; 2016 Sep; 478(2):721-6. PubMed ID: 27498028
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Benzothiazole Derivative as a Novel Mycobacterium tuberculosis Shikimate Kinase Inhibitor: Identification and Elucidation of Its Allosteric Mode of Inhibition.
    Mehra R; Rajput VS; Gupta M; Chib R; Kumar A; Wazir P; Khan IA; Nargotra A
    J Chem Inf Model; 2016 May; 56(5):930-40. PubMed ID: 27149193
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rottlerin induces heme oxygenase-1 (HO-1) up-regulation through reactive oxygen species (ROS) dependent and PKC delta-independent pathway in human colon cancer HT29 cells.
    Park EJ; Lim JH; Nam SI; Park JW; Kwon TK
    Biochimie; 2010 Jan; 92(1):110-5. PubMed ID: 19833168
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Screening of antitubercular compound library identifies novel shikimate kinase inhibitors of Mycobacterium tuberculosis.
    Rajput VS; Mehra R; Kumar S; Nargotra A; Singh PP; Khan IA
    Appl Microbiol Biotechnol; 2016 Jun; 100(12):5415-26. PubMed ID: 26887318
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular model of shikimate kinase from Mycobacterium tuberculosis.
    Filgueira de Azevedo W; Canduri F; Simões de Oliveira J; Basso LA; Palma MS; Pereira JH; Santos DS
    Biochem Biophys Res Commun; 2002 Jul; 295(1):142-8. PubMed ID: 12083781
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rottlerin induces apoptosis of HT29 colon carcinoma cells through NAG-1 upregulation via an ERK and p38 MAPK-dependent and PKC δ-independent mechanism.
    Lim JH; Woo SM; Min KJ; Park EJ; Jang JH; Seo BR; Iqbal T; Lee TJ; Kim SH; Choi YH; Kwon TK
    Chem Biol Interact; 2012 Apr; 197(1):1-7. PubMed ID: 22410117
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-based in silico design of a high-affinity dipeptide inhibitor for novel protein drug target Shikimate kinase of Mycobacterium tuberculosis.
    Kumar M; Verma S; Sharma S; Srinivasan A; Singh TP; Kaur P
    Chem Biol Drug Des; 2010 Sep; 76(3):277-84. PubMed ID: 20626408
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Neuroprotective effect of protein kinase C delta inhibitor rottlerin in cell culture and animal models of Parkinson's disease.
    Zhang D; Anantharam V; Kanthasamy A; Kanthasamy AG
    J Pharmacol Exp Ther; 2007 Sep; 322(3):913-22. PubMed ID: 17565007
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Down-regulation of caspase-2 by rottlerin via protein kinase C-delta-independent pathway.
    Basu A; Adkins B; Basu C
    Cancer Res; 2008 Apr; 68(8):2795-802. PubMed ID: 18413747
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria independent of protein kinase C.
    Tillman DM; Izeradjene K; Szucs KS; Douglas L; Houghton JA
    Cancer Res; 2003 Aug; 63(16):5118-25. PubMed ID: 12941843
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure of shikimate kinase from Mycobacterium tuberculosis reveals the binding of shikimic acid.
    Pereira JH; de Oliveira JS; Canduri F; Dias MV; Palma MS; Basso LA; Santos DS; de Azevedo WF
    Acta Crystallogr D Biol Crystallogr; 2004 Dec; 60(Pt 12 Pt 2):2310-9. PubMed ID: 15583379
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rottlerin synergistically enhances imatinib-induced apoptosis of BCR/ABL-expressing cells through its mitochondrial uncoupling effect independent of protein kinase C-delta.
    Kurosu T; Tsuji K; Kida A; Koyama T; Yamamoto M; Miura O
    Oncogene; 2007 May; 26(21):2975-87. PubMed ID: 17130834
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rottlerin inhibits stimulated enzymatic secretion and several intracellular signaling transduction pathways in pancreatic acinar cells by a non-PKC-delta-dependent mechanism.
    Tapia JA; Jensen RT; García-Marín LJ
    Biochim Biophys Acta; 2006 Jan; 1763(1):25-38. PubMed ID: 16364465
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rottlerin induces apoptosis via death receptor 5 (DR5) upregulation through CHOP-dependent and PKC delta-independent mechanism in human malignant tumor cells.
    Lim JH; Park JW; Choi KS; Park YB; Kwon TK
    Carcinogenesis; 2009 May; 30(5):729-36. PubMed ID: 19037087
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: the protective role of autophagy in apoptosis.
    Song KS; Kim JS; Yun EJ; Kim YR; Seo KS; Park JH; Jung YJ; Park JI; Kweon GR; Yoon WH; Lim K; Hwang BD
    Autophagy; 2008 Jul; 4(5):650-8. PubMed ID: 18424913
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structures of Helicobacter pylori shikimate kinase reveal a selective inhibitor-induced-fit mechanism.
    Cheng WC; Chen YF; Wang HJ; Hsu KC; Lin SC; Chen TJ; Yang JM; Wang WC
    PLoS One; 2012; 7(3):e33481. PubMed ID: 22438938
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rottlerin induces pro-apoptotic endoplasmic reticulum stress through the protein kinase C-delta-independent pathway in human colon cancer cells.
    Lim JH; Park JW; Kim SH; Choi YH; Choi KS; Kwon TK
    Apoptosis; 2008 Nov; 13(11):1378-85. PubMed ID: 18807195
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of new potential Mycobacterium tuberculosis shikimate kinase inhibitors through molecular docking simulations.
    Vianna CP; de Azevedo WF
    J Mol Model; 2012 Feb; 18(2):755-64. PubMed ID: 21594693
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rottlerin induces calcium influx and protein degradation in cultured lenses independent of effects on protein kinase C delta.
    Xu SZ
    Basic Clin Pharmacol Toxicol; 2007 Dec; 101(6):459-64. PubMed ID: 17927688
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanisms of apoptosis-induction by rottlerin: therapeutic implications for B-CLL.
    Ringshausen I; Oelsner M; Weick K; Bogner C; Peschel C; Decker T
    Leukemia; 2006 Mar; 20(3):514-20. PubMed ID: 16437144
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.