These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 27500498)

  • 1. Regulation of the vitamin D receptor by vitamin D lactam derivatives.
    Asano L; Waku T; Abe R; Kuwabara N; Ito I; Yanagisawa J; Nagasawa K; Shimizu T
    FEBS Lett; 2016 Sep; 590(18):3270-9. PubMed ID: 27500498
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthetic studies of (23S,25R)-1α,25-dihydroxyvitamin D
    Akagi Y; Nagata A; Odagi M; Nagasawa K
    J Steroid Biochem Mol Biol; 2018 Mar; 177():240-246. PubMed ID: 28757443
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of 1alpha,25-dihydroxyvitamin D3-26,23-lactams (DLAMs), a novel series of 1 alpha,25-dihydroxyvitamin D3 antagonist.
    Kato Y; Nakano Y; Sano H; Tanatani A; Kobayashi H; Shimazawa R; Koshino H; Hashimoto Y; Nagasawa K
    Bioorg Med Chem Lett; 2004 May; 14(10):2579-83. PubMed ID: 15109656
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 25-Dehydro-1alpha-hydroxyvitamin D3-26,23S-lactone antagonizes the nuclear vitamin D receptor by mediating a unique noncovalent conformational change.
    Bula CM; Bishop JE; Ishizuka S; Norman AW
    Mol Endocrinol; 2000 Nov; 14(11):1788-96. PubMed ID: 11075812
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 1alpha,25-Dihydroxyvitamin D(3)-26,23-lactam analogues function as vitamin D receptor antagonists in human and rodent cells.
    Ishizuka S; Kurihara N; Hiruma Y; Miura D; Namekawa J; Tamura A; Kato-Nakamura Y; Nakano Y; Takenouchi K; Hashimoto Y; Nagasawa K; Roodman GD
    J Steroid Biochem Mol Biol; 2008 Jun; 110(3-5):269-77. PubMed ID: 18501591
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural Analysis of VDR Complex with ZK168281 Antagonist.
    Belorusova AY; Chalhoub S; Rovito D; Rochel N
    J Med Chem; 2020 Sep; 63(17):9457-9463. PubMed ID: 32787090
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fine tuning of agonistic/antagonistic activity for vitamin D receptor by 22-alkyl chain length of ligands: 22S-Hexyl compound unexpectedly restored agonistic activity.
    Anami Y; Sakamaki Y; Itoh T; Inaba Y; Nakabayashi M; Ikura T; Ito N; Yamamoto K
    Bioorg Med Chem; 2015 Nov; 23(22):7274-81. PubMed ID: 26515040
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of an alternative ligand-binding pocket in the nuclear vitamin D receptor and its functional importance in 1alpha,25(OH)2-vitamin D3 signaling.
    Mizwicki MT; Keidel D; Bula CM; Bishop JE; Zanello LP; Wurtz JM; Moras D; Norman AW
    Proc Natl Acad Sci U S A; 2004 Aug; 101(35):12876-81. PubMed ID: 15326291
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of the subdomain in the nuclear receptor for the hormonal form of vitamin D3, 1 alpha,25-dihydroxyvitamin D3, vitamin D receptor, that is covalently modified by an affinity labeling reagent.
    Swamy N; Kounine M; Ray R
    Arch Biochem Biophys; 1997 Dec; 348(1):91-5. PubMed ID: 9390178
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand.
    Rochel N; Wurtz JM; Mitschler A; Klaholz B; Moras D
    Mol Cell; 2000 Jan; 5(1):173-9. PubMed ID: 10678179
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structure of the vitamin D nuclear receptor ligand binding domain in complex with a locked side chain analog of calcitriol.
    Rochel N; Hourai S; Pérez-García X; Rumbo A; Mourino A; Moras D
    Arch Biochem Biophys; 2007 Apr; 460(2):172-6. PubMed ID: 17346665
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ligand recognition by the vitamin D receptor.
    Choi M; Yamamoto K; Masuno H; Nakashima K; Taga T; Yamada S
    Bioorg Med Chem; 2001 Jul; 9(7):1721-30. PubMed ID: 11425573
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Corepressor excess shifts the two-side chain vitamin D analog Gemini from an agonist to an inverse agonist of the vitamin D receptor.
    Gonzalez MM; Samenfeld P; Peräkylä M; Carlberg C
    Mol Endocrinol; 2003 Oct; 17(10):2028-38. PubMed ID: 12843209
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Assessment of the free binding energy of 1,25-dihydroxyvitamin D3 and its analogs with the human VDR receptor model.
    Kamel K; Kolinski A
    Acta Biochim Pol; 2012; 59(4):653-60. PubMed ID: 23074704
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Vitamin D receptor 2016: novel ligands and structural insights.
    Maestro MA; Molnár F; Mouriño A; Carlberg C
    Expert Opin Ther Pat; 2016 Nov; 26(11):1291-1306. PubMed ID: 27454349
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A structural basis for the species-specific antagonism of 26,23-lactones on vitamin D signaling.
    Peräkylä M; Molnár F; Carlberg C
    Chem Biol; 2004 Aug; 11(8):1147-56. PubMed ID: 15324816
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Natural metabolites of 1alpha,25-dihydroxyvitamin D(3) retain biologic activity mediated through the vitamin D receptor.
    Harant H; Spinner D; Reddy GS; Lindley IJ
    J Cell Biochem; 2000 Apr; 78(1):112-20. PubMed ID: 10797570
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Relationship between Structure and Conformational Change of the Vitamin D Receptor Ligand Binding Domain in 1α,25-Dihydroxyvitamin D3 Signaling.
    Wan LY; Zhang YQ; Chen MD; Du YQ; Liu CB; Wu JF
    Molecules; 2015 Nov; 20(11):20473-86. PubMed ID: 26593892
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular structure of the rat vitamin D receptor ligand binding domain complexed with 2-carbon-substituted vitamin D3 hormone analogues and a LXXLL-containing coactivator peptide.
    Vanhooke JL; Benning MM; Bauer CB; Pike JW; DeLuca HF
    Biochemistry; 2004 Apr; 43(14):4101-10. PubMed ID: 15065852
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functionalization at C-12 of 1alpha,25-dihydroxyvitamin D(3) strongly modulates the affinity for the vitamin D receptor (VDR).
    González-Avión XC; Mouriño A
    Org Lett; 2003 Jun; 5(13):2291-3. PubMed ID: 12816431
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.